Publications

Immunity

Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

In vivo dosimetry during conformal radiotherapy: requirements for and findings of a routine procedure.

Pharmacological research

Pharmacokinetics of paclitaxel administered as a 3-hour or 96-hour infusion.

British journal of cancer

Oral topotecan: bioavailablity and effect of food co-administration.

BioEssays : news and reviews in molecular, cellular and developmental biology

Integrins: alternative splicing as a mechanism to regulate ligand binding and integrin signaling events.

Current opinion in genetics & development

The trithorax-group and polycomb-group chromatin modifiers: implications for disease.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase I and pharmacokinetic study of irinotecan administered as a low-dose, continuous intravenous infusion over 14 days in patients with malignant solid tumors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase I and pharmacokinetic study of a daily times 5 short intravenous infusion schedule of 9-aminocamptothecin in a colloidal dispersion formulation in patients with advanced solid tumors.

Cancer research

Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis.

15-05-1999

The Journal of biological chemistry

Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation.

14-05-1999

Cancer chemotherapy and pharmacology

Paclitaxel in the treatment of human immunodeficiency virus 1-associated Kaposi's sarcoma--drug-drug interactions with protease inhibitors and a nonnucleoside reverse transcriptase inhibitor: a case report study.

13-05-1999

Cancer

The development of a prognostic score for patients with parotid carcinoma.

01-05-1999

British journal of pharmacology

Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug.

01-05-1999

Trends in genetics : TIG

Mouse models for cancer at center stage. AACR special meeting: Cancer Biology and the Mutant Mouse: New Methods, New Models, New Insights, Keystone Colorado, USA, 31 January-5 February 1999.

01-05-1999

Journal of chromatography. B, Biomedical sciences and applications

Quantification of topotecan and its metabolite N-desmethyltopotecan in human plasma, urine and faeces by high-performance liquid chromatographic methods.

30-04-1999

Advanced drug delivery reviews

P-Glycoprotein, a gatekeeper in the blood-brain barrier.

05-04-1999

European journal of immunology

Systemic T cell expansion during localized viral infection.

Immunology today

Turning the immune system on.

Cancer treatment reviews

Clinical pharmacology of anticancer agents in relation to formulations and administration routes.

Cancer research

Identification and characterization of collaborating oncogenes in compound mutant mice.

The Journal of clinical investigation

Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis.

Seminars in cell & developmental biology

Cellular memory of transcriptional states by Polycomb-group proteins.

The Journal of pharmacology and experimental therapeutics

Comparative pharmacokinetics of vinblastine after a 96-hour continuous infusion in wild-type mice and mice lacking mdr1a P-glycoprotein.

Cancer chemotherapy and pharmacology

A single 24-hour plasma sample does not predict the carboplatin AUC from carboplatin-paclitaxel combinations or from a high-dose carboplatin-thiotepa-cyclophosphamide regimen.

Biochimica et biophysica acta

CSH Meeting on Cancer Genetics 1998.

25-03-1999

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancer.

01-03-1999

British journal of cancer

Phase II trial of topically applied miltefosine solution in patients with skin-metastasized breast cancer.

01-03-1999

Matrix biology : journal of the International Society for Matrix Biology

Biology and function of hemidesmosomes.

Cancer

Cognitive deficits after postoperative adjuvant chemotherapy for breast carcinoma.

British journal of cancer

Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG).

Therapeutic drug monitoring

Sampling technique from central venous catheters proves critical for pharmacokinetic studies.

British journal of cancer

Bioavailability and toxicity after oral administration of m-iodobenzylguanidine (MIBG).