Publications

Anti-cancer drugs

Metabolism and excretion of paclitaxel after oral administration in combination with cyclosporin A and after i.v. administration.

Anti-cancer drugs

Pharmaceutical development of anticancer agents derived from marine sources.

Clinical cancer research : an official journal of the American Association for Cancer Research

Increased oral bioavailability of paclitaxel by GF120918 in mice through selective modulation of P-glycoprotein.

Nature genetics

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

Clinical pharmacokinetics

Pharmacokinetically guided administration of chemotherapeutic agents.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Extensive cytoreductive surgery combined with intra-operative intraperitoneal perfusion with cisplatin under hyperthermic conditions (OVHIPEC) in patients with recurrent ovarian cancer: a feasibility pilot.

Journal of the National Cancer Institute

Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan.

18-10-2000

Cancer research

Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance.

15-10-2000

Nature

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch.

12-10-2000

Oncogene

p27kip1-independent cell cycle regulation by MYC.

05-10-2000

Cancer gene therapy

Lymphoid abnormalities in CD40 ligand transgenic mice suggest the need for tight regulation in gene therapy approaches to hyper immunoglobulin M (IgM) syndrome

Therapeutic drug monitoring

Determination of ifosfamide, 2- and 3-dechloroethyifosfamide using gas chromatography with nitrogen-phosphorus or mass spectrometry detection.

Radiation research

In vitro and in vivo expression of endothelial von Willebrand factor and leukocyte accumulation after fractionated irradiation.

Anti-cancer drugs

Cremophor EL pharmacokinetics in a phase I study of paclitaxel (Taxol) and carboplatin in non-small cell lung cancer patients.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

How are you feeling? Who wants to know? Patients' and oncologists' preferences for discussing health-related quality-of-life issues.

15-09-2000

Lancet (London, England)

Risk and prognosis of endometrial cancer after tamoxifen for breast cancer. Comprehensive Cancer Centres' ALERT Group. Assessment of Liver and Endometrial cancer Risk following Tamoxifen.

09-09-2000

Cancer chemotherapy and pharmacology

Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens.

06-09-2000

Nature medicine

In situ detection of virus- and tumor-specific T-cell immunity.

01-09-2000

Journal of chromatography. B, Biomedical sciences and applications

Simple and selective determination of the cyclophosphamide metabolite phosphoramide mustard in human plasma using high-performance liquid chromatography.

18-08-2000

The Annals of pharmacotherapy

Cyclosporine-induced anaphylaxis.

06-08-2000

PDA journal of pharmaceutical science and technology

Pharmaceutical development of a parenteral lyophilized formulation of the novel antitumor agent aplidine.

06-08-2000

Nederlands tijdschrift voor geneeskunde

[Second primary tumors in patients treated at an early age for Hodgkin's disease; consequences for the follow-up].

05-08-2000

Anti-cancer drugs

The clinical pharmacology of alkylating agents in high-dose chemotherapy.

01-08-2000

British journal of cancer

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export.

01-08-2000

Investigational new drugs

The oral route for the administration of cytotoxic drugs: strategies to increase the efficiency and consistency of drug delivery.

01-08-2000

Cancer chemotherapy and pharmacology

Feasibility and pharmacokinetics of intraperitoneal suramin in advanced malignancy.

27-07-2000

The Journal of cell biology

Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology.

10-07-2000

Cell

Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage.

07-07-2000

Oncogene

A genetic screen to identify genes that rescue the slow growth phenotype of c-myc null fibroblasts.

06-07-2000

Molecular and biochemical parasitology

Tandemly repeated DNA is a target for the partial replacement of thymine by beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.

01-07-2000

Cell and tissue research

Radiation-induced apoptosis.

01-07-2000

Proceedings of the National Academy of Sciences of the United States of America

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs.

20-06-2000

American journal of epidemiology

Reporting bias in case-control studies on induced abortion and breast cancer.

15-06-2000

Clinical pharmacology and therapeutics

Validation of techniques for the prediction of carboplatin exposure: application of Bayesian methods.

British journal of clinical pharmacology

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase I and pharmacokinetic study of oral paclitaxel.

Patient education and counseling

Psychological distress two years after diagnosis of breast cancer: frequency and prediction.