Publications

Bioorganic & medicinal chemistry

Design, Synthesis, and Biological Implications of Autotaxin inhibitors with a Three-Point lock binding mode.

01-07-2025

Contemporary clinical trials communications

Pharmacokinetic boosting of olaparib: Study protocol of a multicentre, open-label, randomised, non-inferiority trial (PROACTIVE-B).

01-06-2025

NAR genomics and bioinformatics

Detecting ribosome collisions with differential rRNA fragment analysis in ribosome profiling data.

01-06-2025

Biomedical chromatography : BMC

Development and Validation of a Rapid and Simple LC-MS/MS Method for Quantification of the Anti-Microtubule, Anti-Cancer Agent ABT-751 in Human and Mouse Plasma and Mouse Tissues.

01-06-2025

Proceedings of the National Academy of Sciences of the United States of America

Reply to Mishima et al.: MALT1 modulates GPX4 expression by regulating its stability.

20-05-2025

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Pembrolizumab Plus Docetaxel Versus Docetaxel for Previously Treated Metastatic Castration-Resistant Prostate Cancer: The Randomized, Double-Blind, Phase III KEYNOTE-921 Trial.

10-05-2025

Genome biology

Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations.

09-05-2025

Clinical pharmacology and therapeutics

Implementing Pre-Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects.

07-05-2025

Nature

PLA2G15 is a BMP hydrolase and its targeting ameliorates lysosomal disease.

07-05-2025

The Lancet. Oncology

Association between risk-reducing surgeries and survival in young BRCA carriers with breast cancer: an international cohort study.

07-05-2025

Developmental cell

Stemness in flux: Dissecting intestinal crypt organization with multimodal approaches.

05-05-2025

Cancer cell

Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread.

05-05-2025

European journal of cancer (Oxford, England : 1990)

Added prognostic value of circulating tumor cell numbers in CSF of patients with leptomeningeal metastasis from epithelial tumors.

02-05-2025

European journal of cancer (Oxford, England : 1990)

Immune checkpoint inhibition in metastatic or non-resectable melanoma after failure of adjuvant anti-PD-1 treatment. A EUMelaReg real-world evidence study.

02-05-2025

European journal of cancer (Oxford, England : 1990)

Flexibility in patient-reported outcome and health-related quality of life measurement: The EORTC Quality of Life Group measurement strategy.

02-05-2025

European journal of cancer (Oxford, England : 1990)

Guidance for discussants of randomized cancer trials at major meetings.

02-05-2025

PharmacoEconomics - open

Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer.

01-05-2025

European journal of radiology

RECIST progression: Patterns among target, non-target, non-measurable and new lesions progression.

01-05-2025

Oral oncology

Comparison of cisplatin-induced hearing loss in different durations of infusion and volume of hydration schedules in head and neck squamous cell carcinoma patients treated with cisplatin-based chemoradiation.

01-05-2025

International journal of radiation oncology, biology, physics

Radiation Doses to the Breast and Predicted Breast Cancer Risk Among Patients Treated for Hodgkin Lymphoma With Modern Radiation Therapy.

01-05-2025

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Early Cost-Effectiveness Analysis of Using Whole-Genome Sequencing for Patients With Castration-Resistant Prostate Cancer.

01-05-2025

Journal of biomedical optics

Toward handheld optically guided biopsy combining diffuse reflectance spectroscopy and autofluorescence.

01-05-2025

Patient education and counseling

Through the lens of oncologists when communicating with non-Western migrants about cancer diagnosis, treatment, and prognosis: Results from a Dutch online survey.

01-05-2025

European radiology

Added value of body MRI to detect primary abdominal malignancies in the diagnostic work-up of patients with adenocarcinoma of unknown primary.

01-05-2025

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Association between dose to cardiac structures and overall survival: A multivariable analysis in a large, multi-institutional database of stage III NSCLC patients with external validation.

01-05-2025

PharmacoEconomics

Towards Recommendations for Cost-Effectiveness Analysis of Predictive, Prognostic, and Serial Biomarker Tests in Oncology.

01-05-2025

The Lancet. Oncology

Defining the role of pragmatic clinical trials in cancer clinical research: outcomes of a collaborative workshop hosted by the European Organisation for Research and Treatment of Cancer.

01-05-2025

The Journal of pathology

Afadin loss induces breast cancer metastasis through destabilisation of E-cadherin to F-actin linkage.

01-05-2025

European radiology

Imaging in pelvic exenteration-a multidisciplinary practice guide from the ESGAR-SAR-ESUR-PelvEx collaborative group.

01-05-2025

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Severity of internal lymphedema in unilateral or bilateral radiotherapy patients: An exploratory study.

01-05-2025

Biomedical chromatography : BMC

Advancing Therapeutic Drug Monitoring for Oral Targeted Anticancer Drugs: From Hospital-Based Towards Home-Sampling.

01-05-2025

EClinicalMedicine

Genetic predisposition in sarcomas: clinical implications and management.

01-05-2025

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Long-term health-related quality of life among adolescent and young adult breast cancer survivors.

01-05-2025

Cancer research

Large-Scale Characterization of Orthotopic Cell Line-Derived Xenografts Identifies TGF-β Signaling as a Key Regulator of Breast Cancer Morphology and Aggressiveness.

30-04-2025

Acta oncologica (Stockholm, Sweden)

Development and the need for implementation of a health-related quality of life measurement strategy for patients with soft tissue sarcoma undergoing preoperative radiotherapy.

30-04-2025

Magma (New York, N.Y.)

Beyond Gleason grading: MRI radiomics to differentiate cribriform growth from non-cribriform growth in prostate cancer men.

29-04-2025

British journal of cancer

Rechallenge of ipilimumab and nivolumab in advanced melanoma patients after previous ipilimumab-based therapy.

29-04-2025

European urology oncology

Novel Molecular Biomarkers to Guide Treatment Decision-making in Metastatic Urothelial Cancer-A Patient Cohort Analysis.

28-04-2025

European radiology

Detection rates for prostate cancer using PI-RADS 2.1 upgrading rules in transition zone lesions align with risk assessment categories: a systematic review and meta-analysis.

27-04-2025

eLife

Major nuclear locales define nuclear genome organization and function beyond A and B compartments.

25-04-2025

Hormones (Athens, Greece)

Quality of life in thyroid cancer survivors with and without permanent hypoparathyroidism.

23-04-2025

Cell reports

SRBD1, a highly conserved gene required for chromosome individualization.

22-04-2025

JCI insight

G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor.

22-04-2025

European journal of cancer (Oxford, England : 1990)

Durable responses upon short-term addition of targeted therapy to anti-PD1 in advanced melanoma patients: 5-year progression-free and overall survival update of the IMPemBra trial.

19-04-2025

Blood

Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of diffuse large B-cell lymphoma.

17-04-2025

Scientific reports

Case-only analysis in small studies of predictive biomarkers.

16-04-2025

British journal of cancer

Adjuvant BRAF/MEK versus anti-PD-1 in BRAF-mutant melanoma: a propensity score matched survival analysis.

15-04-2025

Digestive diseases and sciences

Developing a New Stool Test for Colorectal Cancer Screening, the multitargetFIT (mtFIT).

15-04-2025

European journal of cancer (Oxford, England : 1990)

Assisted reproductive technology in young BRCA carriers with a pregnancy after breast cancer: An international cohort study.

14-04-2025

Cancer cell

Learning the language of T cell receptors through large-scale screening.

14-04-2025