Publications

Practical radiation oncology

Simulation of Focal Boosting in Online Adaptive MRI-Guided SBRT for Patients With Locally Advanced Prostate Cancer With Seminal Vesicle Involvement.

13-11-2024

Cell host & microbe

Longitudinal analysis of the gut microbiota during anti-PD-1 therapy reveals stable microbial features of response in melanoma patients.

13-11-2024

Scientific reports

Colorectal carcinoma progression is not influenced by the pseudokinase PEAK1.

12-11-2024

JCI insight

Diversity of the immune microenvironment and response to checkpoint inhibitor immunotherapy in mucosal melanoma.

08-11-2024

The New England journal of medicine

Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma.

07-11-2024

Journal for immunotherapy of cancer

TMED inhibition suppresses cell surface PD-1 expression and overcomes T cell dysfunction.

07-11-2024

Nature communications

An explainable longitudinal multi-modal fusion model for predicting neoadjuvant therapy response in women with breast cancer.

07-11-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Local control and toxicity after stereotactic radiotherapy in brain metastases patients and the impact of novel systemic treatments.

01-11-2024

Nature genetics

Base editing screens define the genetic landscape of cancer drug resistance mechanisms.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Seven-year analysis of adjuvant pembrolizumab versus placebo in stage III melanoma in the EORTC1325 / KEYNOTE-054 trial.

01-11-2024

Health policy and technology

Perspectives on access to imaging digital health records in oncology: A mixed methods systematic review.

01-11-2024

Trends in biochemical sciences

The quest to identify ADP-ribosylation readers: methodological advances.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Adjuvant immunotherapy in older patients with stage III and resected stage IV melanoma: Toxicity and recurrence-free survival outcomes from the Dutch melanoma treatment registry.

01-11-2024

Nature medicine

Neoadjuvant nivolumab and relatlimab in locally advanced MMR-deficient colon cancer: a phase 2 trial.

01-11-2024

Thyroid : official journal of the American Thyroid Association

The Cancer-Specific Health Economic Measure QLU-C10D is Valid and Responsive for Assessing Health Utility in Patients with Thyroid Cancer.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Improving completion rates of patient-reported outcome measures in cancer clinical trials: Scoping review investigating the implications for trial designs.

01-11-2024

Nature medicine

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

01-11-2024

Nature reviews. Cancer

Macrophages and T cells in metabolic disorder-associated cancers.

01-11-2024

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Freehand SPECT Combined with 3-Dimensional Light Detection and Ranging as Alternative Means of Specimen Scanning During Prostate Cancer Surgery.

01-11-2024

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Using a modified Delphi procedure to select a PRO-CTCAE-based subset for patient-reported symptomatic toxicity monitoring in rectal cancer patients.

01-11-2024

Clinical lung cancer

Association of Serum Biomarkers With Neurocognitive Decline After PCI in Small Cell Lung Cancer: An Exploratory Study of the Phase III NCT01780675 Trial.

01-11-2024

Molecular oncology

A scenario-drafting study to explore potential future implementation pathways of circulating tumor DNA testing in oncology.

01-11-2024

Clinical and translational radiation oncology

Feasibility and safety of single-fraction sub-ablative radiotherapy with systemic therapy in colorectal cancer patients with ≤ 10 metastases: A multicenter pilot study (NCT05375708).

01-11-2024

EMBO reports

Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Nature and management of melanoma recurrences following adjuvant anti-PD-1 based therapy.

01-11-2024

The EMBO journal

Chromatin protein complexes involved in gene repression in lamina-associated domains.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Instrumental activities of daily living in neuro-oncology: International validation of the EORTC IADL-BN32 questionnaire.

01-11-2024

Journal of cancer survivorship : research and practice

Perspectives of patients, partners, primary and hospital-based health care professionals on living with advanced cancer and systemic treatment.

29-10-2024

eLife

Large-scale analysis of the integration of enhancer-enhancer signals by promoters.

28-10-2024

bioRxiv : the preprint server for biology

An integrated view of the structure and function of the human 4D nucleome.

27-10-2024

BJC reports

Long-term survival following anti-PD-(L)1 monotherapy in advanced urothelial cancer and an assessment of potential prognostic clinical factors: a multicentre observational study.

23-10-2024

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Evaluating a digital tool for supporting people affected by breast cancer: a prospective randomized controlled trial-the ADAPT study.

21-10-2024

Nature communications

Cancer treatment monitoring using cell-free DNA fragmentomes.

21-10-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Academic Uphill Battle to Personalize Treatment for Patients With Stage II/III Triple-Negative Breast Cancer.

20-10-2024

Journal of cancer survivorship : research and practice

Concordance between late effects reported by physicians and patients in a cohort of long-term Hodgkin lymphoma survivors: an analysis of data from nine consecutive EORTC-LYSA trials.

18-10-2024

Journal of cancer survivorship : research and practice

Identifying the informational needs and sources of support of Adolescent and Young Adult (AYA) cancer survivors to inform the development of a digital platform.

18-10-2024

Nature communications

OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1^S824.

17-10-2024

Digestive diseases (Basel, Switzerland)

Treatment of Colorectal Lung Metastases: Two Centers Retrospective Study.

16-10-2024

BMJ open

Optimised treatment of patients with enlarged lateral lymph nodes in rectal cancer: protocol of an international, multicentre, prospective registration study after extensive multidisciplinary training (LaNoReC).

16-10-2024

Drug metabolism and disposition: the biological fate of chemicals

Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models.

16-10-2024

International journal of cancer

Adjuvant treatment with anti-PD-1 in acral melanoma: A nationwide study.

15-10-2024

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an LC-MS/MS method for simultaneous quantification of eight drugs in plasma and brain: Application in a pharmacokinetic study in mice.

15-10-2024

Journal of immunology (Baltimore, Md. : 1950)

ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo.

15-10-2024

Cancer cell

Architecture sets the path: Breast cancer subtypes differently shape the early brain metastatic niche.

14-10-2024

BMJ open

Cohort profile: a nationwide study in Dutch CHEK2 c.1100delC families using the infrastructure of the HEreditary Breast and Ovarian cancer study Netherlands - Hebon-CHEK2.

09-10-2024

Journal of cancer survivorship : research and practice

Patient-reported outcomes in cancer survivorship: insights from two decades of population-based PROFILES registry research.

08-10-2024

American journal of epidemiology

Regression calibration of self-reported mobile phone use to optimize quantitative risk estimation in the COSMOS study.

07-10-2024

Molecular pharmaceutics

Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c.

07-10-2024

Communications biology

Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia.

04-10-2024

Structure (London, England : 1993)

The future of integrated structural biology.

03-10-2024