Publications

Nature communications

H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours.

24-05-2024

Acta oncologica (Stockholm, Sweden)

The evolution of precision oncology: The ongoing impact of the Drug Rediscovery Protocol (DRUP).

23-05-2024

Acta oncologica (Stockholm, Sweden)

PCM4EU and PRIME-ROSE: Collaboration for implementation of precision cancer medicine in Europe.

23-05-2024

BMC cancer

Safe Stop IPI-NIVO trial: early discontinuation of nivolumab upon achieving a complete or partial response in patients with irresectable stage III or metastatic melanoma treated with first-line ipilimumab-nivolumab - study protocol.

23-05-2024

Cancers

Internal Responsiveness of EQ-5D-5L and EORTC QLQ-C30 in Dutch Breast Cancer Patients during the First Year Post-Surgery: A Longitudinal Cohort Study.

21-05-2024

Science (New York, N.Y.)

DNA damage induces p53-independent apoptosis through ribosome stalling.

17-05-2024

Molecular cell

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants.

16-05-2024

Scientific reports

Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma.

16-05-2024

International journal of cancer

Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis.

15-05-2024

International journal of cancer

A prediction model for response to immune checkpoint inhibition in advanced melanoma.

15-05-2024

Genome research

Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.

15-05-2024

Heliyon

Fractionated brain X-irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior in mice.

15-05-2024

Journal of cancer survivorship : research and practice

Health-related conditions among long-term cancer survivors diagnosed in adolescence and young adulthood (AYA): results of the SURVAYA study.

13-05-2024

Circulation research

CD151 Maintains Endolysosomal Protein Quality to Inhibit Vascular Inflammation.

10-05-2024

Cancers

Resection Ratios and Tumor Eccentricity in Breast-Conserving Surgery Specimens for Surgical Accuracy Assessment.

09-05-2024

Pediatric rheumatology online journal

Adherence to low-dose methotrexate in children with juvenile idiopathic arthritis using a sensitive methotrexate assay.

07-05-2024

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.

06-05-2024

The British journal of surgery

A surgical navigation system to aid the ablation of vanished colorectal liver metastases.

03-05-2024

The oncologist

Efficacy and Safety of Panitumumab in Patients With RAF/RAS-Wild-Type Glioblastoma: Results From the Drug Rediscovery Protocol.

03-05-2024

British journal of cancer

Combination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma.

01-05-2024

European journal of cancer (Oxford, England : 1990)

Propranolol monotherapy in angiosarcoma - A window-of-opportunity study (PropAngio).

01-05-2024

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Organization of head and neck cancer rehabilitation care: a national survey among healthcare professionals in Dutch head and neck cancer centers.

01-05-2024

Nature medicine

Author Correction: Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial.

01-05-2024

La Radiologia medica

Multi-omics staging of locally advanced rectal cancer predicts treatment response: a pilot study.

01-05-2024

Journal of thoracic imaging

Artificial Intelligence-based Quantification of Pleural Plaque Volume and Association With Lung Function in Asbestos-exposed Patients.

01-05-2024

JAMA otolaryngology-- head & neck surgery

Decisional Conflict and Decision Regret in Head and Neck Oncology: A Systematic Review and Meta-Analysis.

01-05-2024

Critical reviews in oncology/hematology

Patient-reported outcomes in randomized clinical trials of systemic therapy for advanced soft tissue sarcomas in adults: A systematic review.

01-05-2024

JAMA network open

Safety and Tolerability of Online Adaptive High-Field Magnetic Resonance-Guided Radiotherapy.

01-05-2024

European journal of cancer (Oxford, England : 1990)

Evolution of clinical nature, treatment and survival of locally recurrent rectal cancer: Comparative analysis of two national cross-sectional cohorts.

01-05-2024

Computers in biology and medicine

Overcoming data scarcity in radiomics/radiogenomics using synthetic radiomic features.

01-05-2024

EMBO reports

The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing.

01-05-2024

Endoscopy

Post-colonoscopy colorectal cancers in a national fecal immunochemical test-based colorectal cancer screening program.

01-05-2024

Epidemiology (Cambridge, Mass.)

Towards a Clearer Causal Question Underlying the Association Between Cancer and Dementia.

01-05-2024

Cancer

BRAF/MEK inhibitor rechallenge in advanced melanoma patients.

01-05-2024

European urology focus

Differences in Quality of Life between German and Dutch Patients with Prostate Cancer Treated with Robot-assisted Radical Prostatectomy: Implications for International Multicenter Randomized Controlled Trials.

01-05-2024

European journal of cancer (Oxford, England : 1990)

Trastuzumab plus pertuzumab for HER2-amplified advanced colorectal cancer: Results from the drug rediscovery protocol (DRUP).

01-05-2024

Breast cancer research and treatment

Effects of physical exercise during adjuvant chemotherapy for breast cancer on long-term tested and perceived cognition: results of a pragmatic follow-up study.

01-05-2024

Endocrine

The impact of electronic versus paper-based data capture on data collection logistics and on missing scores in thyroid cancer patients.

01-05-2024

Journal of cell science

Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility.

01-05-2024

Annals of oncology : official journal of the European Society for Medical Oncology

Residual disease post neoadjuvant chemo-immunotherapy in early triple-negative breast cancer: does it help tailor adjuvant treatment?

01-05-2024

The Lancet. Oncology

MRI-guided optimisation of neoadjuvant chemotherapy duration in stage II-III HER2-positive breast cancer (TRAIN-3): a multicentre, single-arm, phase 2 study.

01-05-2024

Journal of magnetic resonance imaging : JMRI

Effect of Physical Exercise on MRI-Assessed Brain Perfusion in Chemotherapy-Treated Breast Cancer Patients: A Randomized Controlled Trial.

01-05-2024

Biopreservation and biobanking

The Information Technology (IT) Infrastructure of the Multicenter Archipelago of Ovarian Cancer Research Biobank: A Potential Blueprint for Other Biobanks.

29-04-2024

Journal for immunotherapy of cancer

Interferon-gamma signature as prognostic and predictive marker in macroscopic stage III melanoma.

27-04-2024

Journal of cancer survivorship : research and practice

The prevalence of mild cognitive impairment in breast cancer patients receiving chemotherapy according to the criteria of the National Institute on Aging-Alzheimer's Association (NIA-AA).

26-04-2024

Cell

A pan-cancer analysis of the microbiome in metastatic cancer.

25-04-2024

EJNMMI physics

Quantification of biochemical PSA dynamics after radioligand therapy with [¹⁷⁷Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model.

24-04-2024

NPJ breast cancer

Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program.

24-04-2024

Journal of cancer survivorship : research and practice

Cardiovascular screening outcomes in the Dutch survivorship care program for Hodgkin lymphoma survivors.

23-04-2024

Nature biotechnology

Discovery of tumor-reactive T cell receptors by massively parallel library synthesis and screening.

23-04-2024

H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours.

The evolution of precision oncology: The ongoing impact of the Drug Rediscovery Protocol (DRUP).

PCM4EU and PRIME-ROSE: Collaboration for implementation of precision cancer medicine in Europe.

Safe Stop IPI-NIVO trial: early discontinuation of nivolumab upon achieving a complete or partial response in patients with irresectable stage III or metastatic melanoma treated with first-line ipilimumab-nivolumab - study protocol.

Internal Responsiveness of EQ-5D-5L and EORTC QLQ-C30 in Dutch Breast Cancer Patients during the First Year Post-Surgery: A Longitudinal Cohort Study.

DNA damage induces p53-independent apoptosis through ribosome stalling.

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants.

Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma.

Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis.

A prediction model for response to immune checkpoint inhibition in advanced melanoma.

Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.

Fractionated brain X-irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior in mice.

Health-related conditions among long-term cancer survivors diagnosed in adolescence and young adulthood (AYA): results of the SURVAYA study.

CD151 Maintains Endolysosomal Protein Quality to Inhibit Vascular Inflammation.

Resection Ratios and Tumor Eccentricity in Breast-Conserving Surgery Specimens for Surgical Accuracy Assessment.

Adherence to low-dose methotrexate in children with juvenile idiopathic arthritis using a sensitive methotrexate assay.

Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.

A surgical navigation system to aid the ablation of vanished colorectal liver metastases.

Efficacy and Safety of Panitumumab in Patients With RAF/RAS-Wild-Type Glioblastoma: Results From the Drug Rediscovery Protocol.

Combination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma.

Propranolol monotherapy in angiosarcoma - A window-of-opportunity study (PropAngio).

Organization of head and neck cancer rehabilitation care: a national survey among healthcare professionals in Dutch head and neck cancer centers.

Author Correction: Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial.

Multi-omics staging of locally advanced rectal cancer predicts treatment response: a pilot study.

Artificial Intelligence-based Quantification of Pleural Plaque Volume and Association With Lung Function in Asbestos-exposed Patients.

Decisional Conflict and Decision Regret in Head and Neck Oncology: A Systematic Review and Meta-Analysis.

Patient-reported outcomes in randomized clinical trials of systemic therapy for advanced soft tissue sarcomas in adults: A systematic review.

Safety and Tolerability of Online Adaptive High-Field Magnetic Resonance-Guided Radiotherapy.

Evolution of clinical nature, treatment and survival of locally recurrent rectal cancer: Comparative analysis of two national cross-sectional cohorts.

Overcoming data scarcity in radiomics/radiogenomics using synthetic radiomic features.

The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing.

Post-colonoscopy colorectal cancers in a national fecal immunochemical test-based colorectal cancer screening program.

Towards a Clearer Causal Question Underlying the Association Between Cancer and Dementia.

BRAF/MEK inhibitor rechallenge in advanced melanoma patients.

Differences in Quality of Life between German and Dutch Patients with Prostate Cancer Treated with Robot-assisted Radical Prostatectomy: Implications for International Multicenter Randomized Controlled Trials.

Trastuzumab plus pertuzumab for HER2-amplified advanced colorectal cancer: Results from the drug rediscovery protocol (DRUP).

Effects of physical exercise during adjuvant chemotherapy for breast cancer on long-term tested and perceived cognition: results of a pragmatic follow-up study.

The impact of electronic versus paper-based data capture on data collection logistics and on missing scores in thyroid cancer patients.

Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility.

Residual disease post neoadjuvant chemo-immunotherapy in early triple-negative breast cancer: does it help tailor adjuvant treatment?

MRI-guided optimisation of neoadjuvant chemotherapy duration in stage II-III HER2-positive breast cancer (TRAIN-3): a multicentre, single-arm, phase 2 study.

Effect of Physical Exercise on MRI-Assessed Brain Perfusion in Chemotherapy-Treated Breast Cancer Patients: A Randomized Controlled Trial.

The Information Technology (IT) Infrastructure of the Multicenter Archipelago of Ovarian Cancer Research Biobank: A Potential Blueprint for Other Biobanks.

Interferon-gamma signature as prognostic and predictive marker in macroscopic stage III melanoma.

The prevalence of mild cognitive impairment in breast cancer patients receiving chemotherapy according to the criteria of the National Institute on Aging-Alzheimer's Association (NIA-AA).

A pan-cancer analysis of the microbiome in metastatic cancer.

Quantification of biochemical PSA dynamics after radioligand therapy with [177Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model.

Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program.

Cardiovascular screening outcomes in the Dutch survivorship care program for Hodgkin lymphoma survivors.

Discovery of tumor-reactive T cell receptors by massively parallel library synthesis and screening.

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Quantification of biochemical PSA dynamics after radioligand therapy with [¹⁷⁷Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model.