Publications

Cancer research

Delta-like ligand-Notch1 signalling is selectively modulated by HPV16 E6 to promote squamous cell proliferation and correlates with cervical cancer prognosis.

26-01-2021

Blood advances

Neutrophil specific granule and NETosis defects in gray platelet syndrome.

26-01-2021

Cell reports

A FOXO-dependent replication checkpoint restricts proliferation of damaged cells.

26-01-2021

American journal of obstetrics and gynecology

Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study.

22-01-2021

JMIR research protocols

Long-Term Morbidity and Health After Early Menopause Due to Oophorectomy in Women at Increased Risk of Ovarian Cancer: Protocol for a Nationwide Cross-Sectional Study With Prospective Follow-Up (HARMOny Study).

22-01-2021

Oncoimmunology

T cells expanded from renal cell carcinoma display tumor-specific CD137 expression but lack significant IFN-γ, TNF-α or IL-2 production.

21-01-2021

Hereditary cancer in clinical practice

Recontacting non-BRCA1/2 breast cancer patients for germline CHEK2 c.1100del pathogenic variant testing: uptake and patient experiences.

19-01-2021

Cell reports. Medicine

ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost.

19-01-2021

Dysphagia

The Timed Swallowing Proficiency for Eating and Drinking (SPEAD) Test: Development and Initial Validation of an Instrument to Objectify (Impaired) Swallowing Capacity in Head and Neck Cancer Patients.

18-01-2021

The journals of gerontology. Series A, Biological sciences and medical sciences

Trajectories of Cognitive and Motor Function Between Ages 45 and 90 Years: A Population-Based Study.

18-01-2021

eLife

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells.

18-01-2021

Cancers

A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer.

16-01-2021

Clinical cancer research : an official journal of the American Association for Cancer Research

Neoadjuvant Therapy for Melanoma: A U.S. Food and Drug Administration-Melanoma Research Alliance Public Workshop.

15-01-2021

Nature communications

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair.

15-01-2021

Genome biology

SPIN reveals genome-wide landscape of nuclear compartmentalization.

14-01-2021

Immunity

The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses.

12-01-2021

Neuro-oncology advances

Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling.

08-01-2021

The AAPS journal

Population Pharmacokinetics of Intracellular 5-Fluorouridine 5'-Triphosphate and its Relationship with Hand-and-Foot Syndrome in Patients Treated with Capecitabine.

08-01-2021

NeuroImage. Clinical

Brain structure prior to non-central nervous system cancer diagnosis: A population-based cohort study.

06-01-2021

Proceedings of the National Academy of Sciences of the United States of America

E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes.

05-01-2021

Journal of the National Cancer Institute

Computational Modeling of Neuropsychological Test Performance to Disentangle Impaired Cognitive Processes in Cancer Patients.

04-01-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Radiation oncology in the new virtual and digital era.

01-01-2021

Acta oncologica (Stockholm, Sweden)

Health-related quality of life of long-term advanced melanoma survivors treated with anti-CTLA-4 immune checkpoint inhibition compared to matched controls.

01-01-2021

JAMA oncology

Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcoma: A Nonrandomized Controlled Trial.

01-01-2021

The American journal of surgical pathology

Genomic Profiling Aids Classification of Diagnostically Challenging Uterine Mesenchymal Tumors With Myomelanocytic Differentiation.

01-01-2021

Nature genetics

WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation.

01-01-2021

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Cost-Effectiveness Assessment of Monitoring Abiraterone Levels in Metastatic Castration-Resistant Prostate Cancer Patients.

01-01-2021

Life science alliance

Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes.

01-01-2021

British journal of cancer

Mutational profiles associated with resistance in patients with BRAFV600E mutant colorectal cancer treated with cetuximab and encorafenib +/- binimetinib or alpelisib.

01-01-2021

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Health-related quality of life after interval cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with stage III ovarian cancer.

01-01-2021

Familial cancer

Report of the fifth meeting of the European Consortium 'Care for CMMRD' (C4CMMRD), Leiden, The Netherlands, July 6th 2019.

01-01-2021

Acta crystallographica. Section D, Structural biology

LAHMA: structure analysis through local annotation of homology-matched amino acids.

01-01-2021

The Journal of surgical research

Selecting Image-Guided Surgical Technologies in Oncology: A Surgeon's Perspective.

01-01-2021

European urology

Reply to Alessia Cimadamore, Liang Cheng, Marina Scarpelli, et al's Letter to the Editor re: Alfonso Gómez de Liaño Lista, Nick van Dijk, Guillermo de Velasco Oria de Rueda, et al. Clinical Outcome After Progressing to Frontline and Second-line Anti-PD-1/PD-L1 in Advanced Urothelial Cancer. Eur Urol 2020;77:269-76. Progression and Hyperprogression Versus Pseudoprogression: Morphologic Documentation.

01-01-2021

Breast cancer research and treatment

Risk of heart failure after systemic treatment for early breast cancer: results of a cohort study.

01-01-2021

Annals of the rheumatic diseases

EULAR points to consider for the diagnosis and management of rheumatic immune-related adverse events due to cancer immunotherapy with checkpoint inhibitors.

01-01-2021

Abdominal radiology (New York)

Machine learning-based analysis of CT radiomics model for prediction of colorectal metachronous liver metastases.

01-01-2021

The Lancet. Oncology

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial.

01-01-2021

Journal for immunotherapy of cancer

Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition.

01-01-2021

European urology

A DROP-IN Gamma Probe for Robot-assisted Radioguided Surgery of Lymph Nodes During Radical Prostatectomy.

01-01-2021

Cancer medicine

Risk of breast cancer in women after a salivary gland carcinoma or pleomorphic adenoma in the Netherlands.

01-01-2021

Annals of oncology : official journal of the European Society for Medical Oncology

Assessment of structural chromosomal instability phenotypes as biomarkers of carboplatin response in triple negative breast cancer: the TNT trial.

01-01-2021

European journal of nuclear medicine and molecular imaging

Clinical response assessment on DW-MRI compared with FDG-PET/CT after neoadjuvant chemoradiotherapy in patients with oesophageal cancer.

01-01-2021

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Chromatographic bioanalytical assays for targeted covalent kinase inhibitors and their metabolites.

01-01-2021

Nature protocols

Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH.

01-01-2021

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Diagnosed with a common cancer at an unusual age: causal attributions of survivors of adolescent and young adult colorectal cancer.

01-01-2021

Nature genetics

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.

01-01-2021

Cancer treatment reviews

Erratum to "Prognostic factors in patients with oligometastatic breast cancer - A systematic review". [Cancer treatment Rev. 91 (2020) 102114].

01-01-2021

The FEBS journal

Translation initiation and its relevance in colorectal cancer.

31-12-2020

Cell reports

USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells.

29-12-2020