Publications

European journal of cancer (Oxford, England : 1990)

Adjuvant immunotherapy in older patients with stage III and resected stage IV melanoma: Toxicity and recurrence-free survival outcomes from the Dutch melanoma treatment registry.

30-09-2024

Cancer discovery

Early detection of ovarian cancer using cell-free DNA fragmentomes and protein biomarkers.

30-09-2024

European journal of cancer (Oxford, England : 1990)

Nature and management of melanoma recurrences following adjuvant anti-PD-1 based therapy.

29-09-2024

The Journal of molecular diagnostics : JMD

High Prevalence of Chromosomal Rearrangements and LINE Retrotranspositions Detected in Formalin-Fixed, Paraffin-Embedded Colorectal Cancer Tissue.

26-09-2024

Journal of cancer survivorship : research and practice

"Numbers call for action, personalized narratives provide support and recognition": a qualitative assessment of cancer patients' perspectives on patient-reported outcome measures (PROMs) feedback with narratives.

25-09-2024

The EMBO journal

Chromatin protein complexes involved in gene repression in lamina-associated domains.

25-09-2024

Nucleic acids research

ADARp150 counteracts whole genome duplication.

23-09-2024

European journal of cancer (Oxford, England : 1990)

Instrumental activities of daily living in neuro-oncology: International validation of the EORTC IADL-BN32 questionnaire.

21-09-2024

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Moving beyond barriers: a mixed-method study to develop evidence-based strategies to improve implementation of PROMs in clinical oncology care.

20-09-2024

Cell

Macrophage-mediated myelin recycling fuels brain cancer malignancy.

19-09-2024

Trends in biochemical sciences

The quest to identify ADP-ribosylation readers: methodological advances.

19-09-2024

European journal of cancer (Oxford, England : 1990)

Improving completion rates of patient-reported outcome measures in cancer clinical trials: Scoping review investigating the implications for trial designs.

18-09-2024

EMBO reports

Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy.

18-09-2024

Journal of cancer survivorship : research and practice

Health care utilization up to 11 years after diagnosis among patients with a hematologic malignancy and its association with socioeconomic position.

17-09-2024

CVIR endovascular

Correction: Interventional solutions for post‑surgical problems: a lymphatic leaks review.

17-09-2024

Nature medicine

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

16-09-2024

Annals of hematology

Impact of comorbidity on health-related quality of life in newly diagnosed patients with lymphoma or multiple myeloma: results from the PROFILES-registry.

16-09-2024

ESMO open

Characteristics and clinical outcomes of breast cancer in young BRCA carriers according to tumor histology.

16-09-2024

The New England journal of medicine

Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma.

15-09-2024

The New England journal of medicine

Perioperative Durvalumab with Neoadjuvant Chemotherapy in Operable Bladder Cancer.

15-09-2024

Nature medicine

Neoadjuvant nivolumab and relatlimab in locally advanced MMR-deficient colon cancer: a phase 2 trial.

15-09-2024

Journal of the National Cancer Institute

Histopathological response to chemotherapy and survival of mucinous type gastric cancer.

14-09-2024

Communications biology

Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types.

13-09-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Intra-prostatic recurrences after radiotherapy with focal boost: Location and dose mapping in the FLAME trial.

13-09-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment.

13-09-2024

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an LC-MS/MS method for simultaneous quantification of eight drugs in plasma and brain: Application in a pharmacokinetic study in mice.

12-09-2024

Frontiers in immunology

mRNA-1273 vaccination induces polyfunctional memory CD4 and CD8 T cell responses in patients with solid cancers undergoing immunotherapy or/and chemotherapy.

11-09-2024

Acta oncologica (Stockholm, Sweden)

High-dose chemotherapy for patients with stage III breast cancer with homologous recombination deficiency: a discrete choice experiment among healthcare providers.

10-09-2024

Cancer cell

Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8⁺ T cells.

09-09-2024

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Using a modified Delphi procedure to select a PRO-CTCAE-based subset for patient-reported symptomatic toxicity monitoring in rectal cancer patients.

08-09-2024

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Treatment-related hearing loss in weekly versus triweekly cisplatin chemoradiation for head and neck cancer.

06-09-2024

The oncologist

High expression of phosphoglycerate dehydrogenase predicts poor outcome in patients with high-grade serous ovarian cancer.

06-09-2024

American journal of human genetics

Co-observation of germline pathogenic variants in breast cancer predisposition genes: Results from analysis of the BRIDGES sequencing dataset.

05-09-2024

medRxiv : the preprint server for health sciences

Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.

04-09-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

Efficacy of Pembrolizumab and Biomarker Analysis in Patients with WGS-Based Intermediate to High Tumor Mutational Load: Results from the Drug Rediscovery Protocol.

03-09-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

Maximizing Treatment Opportunities: Assessing Protocol Waivers' Impact on Safety and Outcome in the Drug Rediscovery Protocol.

03-09-2024

Annals of oncology : official journal of the European Society for Medical Oncology

Randomized phase II dose comparison LITESPARK-013 study of belzutifan in patients with advanced clear cell renal cell carcinoma.

02-09-2024

British journal of cancer

Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology - an analysis of the closed cohorts of a multicentre prospective study.

01-09-2024

Cancer chemotherapy and pharmacology

A joint model of longitudinal pharmacokinetic and time-to-event data to study exposure-response relationships: a proof-of-concept study with alectinib.

01-09-2024

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

First-line palliative systemic therapy alternated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for unresectable colorectal peritoneal metastases: A single-arm phase II trial (CRC-PIPAC-II).

01-09-2024

Journal of cell science

Nucleocytoplasmic transport senses mechanical forces independently of cell density in cell monolayers.

01-09-2024

Nature protocols

OBSERVE: guidelines for the refinement of rodent cancer models.

01-09-2024

European journal of cancer (Oxford, England : 1990)

The survival disparity between children and adolescents and young adults (AYAs) with Ewing sarcoma in the Netherlands did not change since the 1990s despite improved survival: A population-based study.

01-09-2024

Trends in cancer

PARPi, BRCA, and gaps: controversies and future research.

01-09-2024

Gynecologic oncology

Effect of reduced follow-up care on patient satisfaction with care among patients with endometrial cancer: The ENSURE randomized controlled trial.

01-09-2024

ESMO open

The clinical use of enfortumab vedotin and pembrolizumab in patients with advanced urothelial carcinoma: using clinical judgement over treatment criteria.

01-09-2024

The Journal of molecular diagnostics : JMD

Mono- and Biallelic Replication-Coupled Gene Editing Discriminates Dominant-Negative and Loss-of-Function Variants of DNA Mismatch Repair Genes.

01-09-2024

BJU international

The psychosocial impact of prostate cancer screening for BRCA1 and BRCA2 carriers.

01-09-2024

European radiology

Artificial intelligence-assisted double reading of chest radiographs to detect clinically relevant missed findings: a two-centre evaluation.

01-09-2024

Nature

Mechanisms that clear mutations drive field cancerization in mammary tissue.

01-09-2024