Publications

Nature communications

Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma.

22-12-2021

European urology

Patterns of Failure Following External Beam Radiotherapy With or Without an Additional Focal Boost in the Randomized Controlled FLAME Trial for Localized Prostate Cancer.

22-12-2021

European journal of cancer (Oxford, England : 1990)

Chemotherapy after immune checkpoint inhibitor failure in metastatic melanoma: a retrospective multicentre analysis.

21-12-2021

BJU international

Clinicopathological predictors of finding additional inguinal lymph node metastases in penile cancer patients after positive dynamic sentinel node biopsy: a European multicentre evaluation.

20-12-2021

Cancer discovery

Plasticity of extrachromosomal and intrachromosomal BRAF amplifications in overcoming targeted therapy dosage challenges.

20-12-2021

Current oncology (Toronto, Ont.)

Phase Ib Study of Atezolizumab Plus Interferon-α with or without Bevacizumab in Patients with Metastatic Renal Cell Carcinoma and Other Solid Tumors.

20-12-2021

EMBO reports

Unexpected gene activation following CRISPR-Cas9-mediated genome editing.

20-12-2021

Insights into imaging

Factors affecting the value of diffusion-weighted imaging for identifying breast cancer patients with pathological complete response on neoadjuvant systemic therapy: a systematic review.

18-12-2021

European urology oncology

Surgical Safety of Deferred Cytoreductive Nephrectomy Following Pretreatment with Immune Checkpoint Inhibitor-based Dual Combination Therapy.

18-12-2021

Laboratory investigation; a journal of technical methods and pathology

A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic target.

17-12-2021

STAR protocols

Generation of mixed murine organoids to model cellular interactions.

17-12-2021

Practical radiation oncology

Quantifying the sensitivity of target dose on intra-fraction displacement in intra-cranial stereotactic radiosurgery.

17-12-2021

The British journal of surgery

Nationwide registry study on trends in localization techniques and reoperation rates in non-palpable ductal carcinoma in situ and invasive breast cancer.

17-12-2021

Science (New York, N.Y.)

An atlas of intratumoral T cells.

17-12-2021

ESMO open

The impact of COVID-19 on oncology professionals-one year on: lessons learned from the ESMO Resilience Task Force survey series.

17-12-2021

Cancers

Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer.

16-12-2021

Cancers

Differences in Internet Use and eHealth Needs of Adolescent and Young Adult Versus Older Cancer Patients; Results from the PROFILES Registry.

16-12-2021

British journal of cancer

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

15-12-2021

Cancer research

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.

15-12-2021

Journal of cell science

The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation.

15-12-2021

Cancer

Symptom clusters in 1330 survivors of 7 cancer types from the PROFILES registry: A network analysis.

15-12-2021

Clinical cancer research : an official journal of the American Association for Cancer Research

Precision Dosing of Targeted Therapies Is Ready for Prime Time.

15-12-2021

Blood advances

GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.

14-12-2021

Cell reports

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer.

14-12-2021

Breast (Edinburgh, Scotland)

Effects of chemotherapy on contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: A nationwide cohort study.

14-12-2021

Journal of medical Internet research

Web-Based Return of Individual Patient-Reported Outcome Results Among Patients With Lymphoma: Randomized Controlled Trial.

14-12-2021

Urologic oncology

Prognostic markers in invasive bladder cancer: FGFR3 mutation status versus P53 and KI-67 expression: a multi-center, multi-laboratory analysis in 1058 radical cystectomy patients.

11-12-2021

Abdominal radiology (New York)

Differences in the distribution of peritoneal metastases in right- versus left-sided colon cancer on MRI.

11-12-2021

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Brain White Matter Microstructure as a Risk Factor for Cognitive Decline After Chemotherapy for Breast Cancer.

10-12-2021

Clinical genitourinary cancer

A Serendipitous Preoperative Trial of Combined Ipilimumab Plus Nivolumab for Localized Prostate Cancer.

10-12-2021

GigaScience

Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA-minus RNA sequencing data.

09-12-2021

Proceedings of the National Academy of Sciences of the United States of America

Predicting patient response with models trained on cell lines and patient-derived xenografts by nonlinear transfer learning.

07-12-2021

Seminars in immunology

Impact of cancer cell-intrinsic features on neutrophil behavior.

06-12-2021

Developmental cell

Distinct contributions of partial and full EMT to breast cancer malignancy.

06-12-2021

Molecular pharmaceutics

P-Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib.

06-12-2021

Nature biotechnology

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

06-12-2021

Cancer research

A microfluidic cancer-on-chip platform predicts drug response using organotypic tumor slice culture.

06-12-2021

Genome medicine

Germline breast cancer susceptibility genes, tumor characteristics, and survival.

02-12-2021

Annals of oncology : official journal of the European Society for Medical Oncology

Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up.

01-12-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Deep learning model for automatic contouring of cardiovascular substructures on radiotherapy planning CT images: Dosimetric validation and reader study based clinical acceptability testing.

01-12-2021

PharmacoEconomics

Early Cost Effectiveness of Whole-Genome Sequencing as a Clinical Diagnostic Test for Patients with Inoperable Stage IIIB,C/IV Non-squamous Non-small-Cell Lung Cancer.

01-12-2021

Dysphagia

The Timed Swallowing Proficiency for Eating and Drinking (SPEAD) Test: Development and Initial Validation of an Instrument to Objectify (Impaired) Swallowing Capacity in Head and Neck Cancer Patients.

01-12-2021

Breast (Edinburgh, Scotland)

Contralateral parenchymal enhancement on MRI is associated with tumor proteasome pathway gene expression and overall survival of early ER+/HER2-breast cancer patients.

01-12-2021

Annals of oncology : official journal of the European Society for Medical Oncology

Outcome without any adjuvant systemic treatment in stage I ER+/HER2- breast cancer patients included in the MINDACT trial.

01-12-2021

Journal of palliative medicine

High-Intensity Care in the End-of-Life Phase of Castration-Resistant Prostate Cancer Patients: Results from the Dutch CAPRI-Registry.

01-12-2021

Nature reviews. Clinical oncology

International consensus recommendations on key outcome measures for organ preservation after (chemo)radiotherapy in patients with rectal cancer.

01-12-2021

Nature reviews. Clinical oncology

Understanding and overcoming resistance to PARP inhibitors in cancer therapy.

01-12-2021

NPJ breast cancer

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

01-12-2021

Magnetic resonance imaging

Diffusion weighted imaging for evaluation of breast lesions: Comparison between high b-value single-shot and routine readout-segmented sequences at 3 T.

01-12-2021

The Lancet. Oncology

mRNA-1273 COVID-19 vaccination in patients receiving chemotherapy, immunotherapy, or chemoimmunotherapy for solid tumours: a prospective, multicentre, non-inferiority trial.

01-12-2021