Publications

Molecular cell

Transcription factor exchange enables prolonged transcriptional bursts.

21-03-2024

Cell reports. Medicine

Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse.

19-03-2024

ESMO open

Elements of successful patient involvement in clinical cancer trials: a review of the literature.

15-03-2024

Annals of oncology : official journal of the European Society for Medical Oncology

ESMO Clinical Practice Guideline interim update on first-line therapy in advanced urothelial carcinoma.

13-03-2024

Annals of oncology : official journal of the European Society for Medical Oncology

Residual disease post neoadjuvant chemo-immunotherapy in early triple-negative breast cancer: does it help tailor adjuvant treatment?

12-03-2024

European radiology

Artificial intelligence-assisted double reading of chest radiographs to detect clinically relevant missed findings: a two-centre evaluation.

11-03-2024

Cancer cell

Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer.

11-03-2024

Cancer chemotherapy and pharmacology

Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.

08-03-2024

The New England journal of medicine

Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer.

07-03-2024

Molecular cell

Plot twists and cutting corners with atypical SMCs.

07-03-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Baseline shift corrections towards the heart: External validation of the impact on survival in early-stage NSCLC patients.

07-03-2024

Nature medicine

Author Correction: Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial.

06-03-2024

Cancer discovery

Integrative Analyses of Tumor and Peripheral Biomarkers in the Treatment of Advanced Renal Cell Carcinoma.

01-03-2024

Nature

Genetic determinants of micronucleus formation in vivo.

01-03-2024

Journal of surgical oncology

The impact of sex on treatment and outcome in relation to histological subtype in patients with resectable gastric cancer: Results from the randomized CRITICS trial.

01-03-2024

Journal of medical imaging (Bellingham, Wash.)

Automatic hepatic tumor segmentation in intra-operative ultrasound: a supervised deep-learning approach.

01-03-2024

International journal of cancer

Differences in time to patient access to innovative cancer medicines in six European countries.

01-03-2024

Cancer chemotherapy and pharmacology

Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.

01-03-2024

European journal of radiology

Multi-sequence MRI radiomics of colorectal liver metastases: Which features are reproducible across readers?

01-03-2024

Journal of cancer policy

The views of cancer patients of Turkish, Moroccan, Surinamese, and Dutch-Caribbean descent on diagnosis, treatment and prognosis: A systematic literature review.

01-03-2024

The Lancet. Oncology

The multitarget faecal immunochemical test for improving stool-based colorectal cancer screening programmes: a Dutch population-based, paired-design, intervention study.

01-03-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Bosutinib in Resistant and Intolerant Pediatric Patients With Chronic Phase Chronic Myeloid Leukemia: Results From the Phase I Part of Study ITCC054/COG AAML1921.

01-03-2024

European journal of cancer (Oxford, England : 1990)

Real-world health-related quality of life outcomes for patients with resected stage III/IV melanoma treated with adjuvant anti-PD1 therapy.

01-03-2024

European radiology

Outcomes and potential impact of a virtual hands-on training program on MRI staging confidence and performance in rectal cancer.

01-03-2024

Nature protocols

Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice.

01-03-2024

ESMO open

Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer.

01-03-2024

Investigative radiology

Artificial Intelligence-Enhanced Breast MRI: Applications in Breast Cancer Primary Treatment Response Assessment and Prediction.

01-03-2024

European journal of cancer (Oxford, England : 1990)

The side effect registry immuno-oncology (SERIO) - A tool for systematic analysis of immunotherapy-induced side effects.

01-03-2024

The journal of pathology. Clinical research

Aberrant PRDM2 methylation as an early event in serrated lesions destined to evolve into microsatellite-instable colorectal cancers.

01-03-2024

Nature reviews. Clinical oncology

Tumour-infiltrating lymphocyte therapy for patients with advanced-stage melanoma.

01-03-2024

The EMBO journal

PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair.

01-03-2024

EClinicalMedicine

Improving survival in advanced melanoma patients: a trend analysis from 2013 to 2021.

01-03-2024

European urology

Management of Lymph Node-positive Penile Cancer: A Systematic Review.

01-03-2024

Nature

Decoding chromatin states by proteomic profiling of nucleosome readers.

01-03-2024

Medical physics

Development, validation, and simplification of a scanner-specific CT simulator.

01-03-2024

The Journal of pathology

Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.

01-03-2024

Journal for immunotherapy of cancer

Expert consensus guidelines on management and best practices for tumor-infiltrating lymphocyte cell therapy.

29-02-2024

Cancers

The Additional Value of Somatostatin Receptor Positron Emission Computed Tomography ([⁶⁸Ga]Ga-DOTATOC PET/CT) Compared with Magnetic Resonance Imaging of the Head and Neck Region in Paraganglioma Patients: A Pilot Study.

28-02-2024

Sensors (Basel, Switzerland)

Spatial and Spectral Reconstruction of Breast Lumpectomy Hyperspectral Images.

28-02-2024

Medical physics

Impact of cone-beam computed tomography artifacts on dose calculation accuracy for lung cancer.

27-02-2024

Proceedings of the National Academy of Sciences of the United States of America

Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS-mutant cancers.

27-02-2024

European urology

Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy.

27-02-2024

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Assessing patients' needs in the follow-up after treatment for colorectal cancer-a mixed-method study.

26-02-2024

Cancer

Employment outcomes of adolescent and young adult (AYA) cancer survivors and their partners: A Dutch population-based study.

23-02-2024

Cytotherapy

High-dose individualized antithymocyte globulin with therapeutic drug monitoring in high-risk cord blood transplant.

23-02-2024

Nature communications

Adjuvant dendritic cell therapy in stage IIIB/C melanoma: the MIND-DC randomized phase III trial.

23-02-2024

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.

22-02-2024

NPJ systems biology and applications

Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties.

21-02-2024

NPJ precision oncology

A whirl of radiomics-based biomarkers in cancer immunotherapy, why is large scale validation still lacking?

21-02-2024

Breast cancer research : BCR

Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers.

19-02-2024

Transcription factor exchange enables prolonged transcriptional bursts.

Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse.

Elements of successful patient involvement in clinical cancer trials: a review of the literature.

ESMO Clinical Practice Guideline interim update on first-line therapy in advanced urothelial carcinoma.

Residual disease post neoadjuvant chemo-immunotherapy in early triple-negative breast cancer: does it help tailor adjuvant treatment?

Artificial intelligence-assisted double reading of chest radiographs to detect clinically relevant missed findings: a two-centre evaluation.

Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer.

Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.

Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer.

Plot twists and cutting corners with atypical SMCs.

Baseline shift corrections towards the heart: External validation of the impact on survival in early-stage NSCLC patients.

Author Correction: Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial.

Integrative Analyses of Tumor and Peripheral Biomarkers in the Treatment of Advanced Renal Cell Carcinoma.

Genetic determinants of micronucleus formation in vivo.

The impact of sex on treatment and outcome in relation to histological subtype in patients with resectable gastric cancer: Results from the randomized CRITICS trial.

Automatic hepatic tumor segmentation in intra-operative ultrasound: a supervised deep-learning approach.

Differences in time to patient access to innovative cancer medicines in six European countries.

Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.

Multi-sequence MRI radiomics of colorectal liver metastases: Which features are reproducible across readers?

The views of cancer patients of Turkish, Moroccan, Surinamese, and Dutch-Caribbean descent on diagnosis, treatment and prognosis: A systematic literature review.

The multitarget faecal immunochemical test for improving stool-based colorectal cancer screening programmes: a Dutch population-based, paired-design, intervention study.

Bosutinib in Resistant and Intolerant Pediatric Patients With Chronic Phase Chronic Myeloid Leukemia: Results From the Phase I Part of Study ITCC054/COG AAML1921.

Real-world health-related quality of life outcomes for patients with resected stage III/IV melanoma treated with adjuvant anti-PD1 therapy.

Outcomes and potential impact of a virtual hands-on training program on MRI staging confidence and performance in rectal cancer.

Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice.

Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer.

Artificial Intelligence-Enhanced Breast MRI: Applications in Breast Cancer Primary Treatment Response Assessment and Prediction.

The side effect registry immuno-oncology (SERIO) - A tool for systematic analysis of immunotherapy-induced side effects.

Aberrant PRDM2 methylation as an early event in serrated lesions destined to evolve into microsatellite-instable colorectal cancers.

Tumour-infiltrating lymphocyte therapy for patients with advanced-stage melanoma.

PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair.

Improving survival in advanced melanoma patients: a trend analysis from 2013 to 2021.

Management of Lymph Node-positive Penile Cancer: A Systematic Review.

Decoding chromatin states by proteomic profiling of nucleosome readers.

Development, validation, and simplification of a scanner-specific CT simulator.

Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.

Expert consensus guidelines on management and best practices for tumor-infiltrating lymphocyte cell therapy.

The Additional Value of Somatostatin Receptor Positron Emission Computed Tomography ([68Ga]Ga-DOTATOC PET/CT) Compared with Magnetic Resonance Imaging of the Head and Neck Region in Paraganglioma Patients: A Pilot Study.

Spatial and Spectral Reconstruction of Breast Lumpectomy Hyperspectral Images.

Impact of cone-beam computed tomography artifacts on dose calculation accuracy for lung cancer.

Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS-mutant cancers.

Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy.

Assessing patients' needs in the follow-up after treatment for colorectal cancer-a mixed-method study.

Employment outcomes of adolescent and young adult (AYA) cancer survivors and their partners: A Dutch population-based study.

High-dose individualized antithymocyte globulin with therapeutic drug monitoring in high-risk cord blood transplant.

Adjuvant dendritic cell therapy in stage IIIB/C melanoma: the MIND-DC randomized phase III trial.

Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.

Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties.

A whirl of radiomics-based biomarkers in cancer immunotherapy, why is large scale validation still lacking?

Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers.

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The Additional Value of Somatostatin Receptor Positron Emission Computed Tomography ([⁶⁸Ga]Ga-DOTATOC PET/CT) Compared with Magnetic Resonance Imaging of the Head and Neck Region in Paraganglioma Patients: A Pilot Study.