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Response to chemotherapy can be predicted using patient-derived organoids
There is a great need for a test that can predict which patients
will respond to chemotherapy and which will not. In a
clinical study with 61 metastatic colorectal cancer patients,
researchers from the Netherlands Cancer Institute, led by Emile
Voest, now showed that a specific second-line
chemotherapy treatment can first be tested on organoids: these
are 'mini tumours' that have been laboratory grown from a
small piece of the same patients' tumour tissue.
The NKI has opened a call for two positions: one for a
(junior) group leader in a research topic that synergizes with the
ongoing research at the NKI and another one with a focus on