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Over the last five years Jane mainly investigated how cancer
cells are vulnerable because they need a lot of nutrients, and how
we can use this vulnerability against them. On June 3rd
she will defend her thesis - online because of covid-19.
Thesis defense Colinda Scheele: stem cell behavior in mammary glands
On May 7, Netherlands Cancer Institute researcher Colinda
Scheele received her PhD degree cum laude. She could easily be
considered a behavioral biologist, although instead of bonobos or
zebra finches, she observed the behavior of generations of stem
cells in healthy mammary tissue and mammary tumors in mice - live,
in 3D, through a special microscope. One of the things she
discovered was that only a small population of tumor cells in the
mammary tumor - the cancer stem cells - drives a tumor to be
invasive and life-threatening.