Publications

EBioMedicine

Combining cell-free DNA fragmentomes and total tumour volume improves prognostication and tumour response evaluation in patients with colorectal cancer liver metastases.

Human gene therapy

In Remembrance of Professor Zelig Eshhar: A Life Committed to CAR-T.

Nature

Inhibitors supercharge kinase turnover through native proteolytic circuits.

Nature

An integrated view of the structure and function of the human 4D nucleome.

Occupational medicine (Oxford, England)

Night shift work in early pregnancy and risk of preterm birth among Dutch nurses in the Nightingale Study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Online dose-adaptive radiotherapy considerably reduces irradiated volume in rectal cancer radiotherapy.

JCO clinical cancer informatics

Knowledge Representation of a Multicenter Adolescent and Young Adult Cancer Infrastructure: Development of the STRONG AYA Knowledge Graph.

Journal of molecular biology

Imaging the Central Dogma of Molecular Biology: Single Molecules to Single Cells.

Nature

Fasting boosts breast cancer therapy efficacy via glucocorticoid activation.

The Lancet. Oncology

Development of a core outcome set for adolescents and young adults with cancer.

European urology open science

Long-term Real-world Survival Outcomes with Dual Immune Checkpoint Blockade in Synchronous Metastatic Renal Cell Carcinoma: Implications for the Design of Prospective Cytoreductive Nephrectomy Trials.

Human gene therapy

In Remembrance of Professor Zelig Eshhar: A Life Committed to CAR-T.

Statistics in medicine

Multiple Testing of Mix-and-Match Feature Sets in Multi-Omics.

Nature

Tumour-reactive heterotypic CD8 T cell clusters from clinical samples.

BMJ open

Hospital-based real-world evidence in health technology assessment: insights from a scoping review of European, Australian and North American guidance and expert interviews.

31-12-2025

Key Publication

Journal of anatomy

Neural modulation of ocular immunity: Exploring a sympathetic-macrophage neuroimmune link in the human ciliary body.

30-12-2025

The British journal of surgery

Health-related quality of life of patients undergoing active surveillance versus standard surgery for oesophageal cancer (SANO trial).

24-12-2025

The British journal of surgery

Circulating tumour DNA in patients with stage III colon cancer: multicentre prospective PROVENC3 study.

24-12-2025

Prostate cancer and prostatic diseases

Reducing adverse effects in hypofractionated radiotherapy for prostate cancer: Clinical evidence and emerging mitigation strategies.

23-12-2025

Journal of translational medicine

Diffuse reflectance spectroscopy for enhanced diagnostic precision in breast cancer.

20-12-2025

JCO oncology practice

Budget Impact Analysis of Hyperthermic Intraperitoneal Chemotherapy With Interval Cytoreductive Surgery in Ovarian Cancer.

19-12-2025

Molecular cell

Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors.

18-12-2025

Proceedings of the National Academy of Sciences of the United States of America

Galectin-9 binding to HLA-DR in dendritic cells controls immune synapse formation and T cell proliferation.

16-12-2025

Cell reports. Medicine

CfDNA-based copy-number dynamics during anti-PD1 treatment in metastatic triple negative breast cancer.

16-12-2025

Journal of pharmaceutical and biomedical analysis

LC-MS/MS method development and validation for novel targeted anticancer therapies adagrasib, capmatinib, ensartinib, entrectinib, larotrectinib, lorlatinib, pralsetinib, selpercatinib and sotorasib.

Journal of clinical pathology

Prognostic value of immunohistochemical markers of intratumoral hypoxia in pregnancy-associated breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Prognosis and Biological Characteristics of ER-Low Metastatic Breast Cancer: Results from a Multicenter Cohort and the TONIC Trial.

Cancer

Cognitive function during endocrine treatment with or without cyclin-dependent kinase 4/6 inhibitors for advanced breast cancer.

CA: a cancer journal for clinicians

Advanced Urologic Cancer Consensus Conference (AUC3) 2025: Expert consensus on the management of renal cell and urinary tract cancers.

13-12-2025

Science advances

Histone methyltransferase DOT1L maintains cell state and restricts cytotoxic potential of CD8 T cells.

12-12-2025

Cell

Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions.

11-12-2025

Mammalian genome : official journal of the International Mammalian Genome Society

A quality framework for cryopreserved rodent disease models: INFRAFRONTIER quality principles in EMMA archiving and distribution.

10-12-2025

European journal of cancer (Oxford, England : 1990)

The use of EORTC QLQ-C30 Summary Score in cancer research and its performance as compared with the EORTC QLQ-C30 Global Health/Quality of Life scale: A systematic review and comparative analysis of effect sizes.

European journal of cancer (Oxford, England : 1990)

Predicting acute coronary events after breast cancer radiotherapy: Integrating baseline cardiovascular risk, systemic therapy, and cardiac radiation dose in the MEDIRAD BRACE study.

Proceedings of the National Academy of Sciences of the United States of America

Distinct transcription factor interactions drive HOXB13 activity in different stages of prostate cancer.

BMC medical imaging

Hypoxia and cribriform growth in prostate cancer - establishing a link via MRI.

Nature communications

Mammo-AGE: deep learning estimation of breast age from mammograms.

08-12-2025

Nature communications

Pre-existing and early cellular immune factors correlate with functionally complete protection against primary controlled human SARS-CoV-2 infection.

07-12-2025

Cancers

High-Dose Transarterial Radioembolization of Hepatic Metastases Using Yttrium-90 Resin Microspheres.

05-12-2025

BMJ open

Quality and safety management of advanced medical technologies in home care organisations in the Netherlands: a qualitative survey at the tactical level.

04-12-2025

BMJ open

Transtympanic sodium thiosulphate to prevent cisplatin-related hearing loss: a protocol for randomised controlled multicentre phase III trial, the SOUND trial.

03-12-2025

Biophysical journal

Long-read nucleosome mapping of single chromatin fibers using DNA methylation and nanopore sequencing.

02-12-2025

Nature communications

Aberrant neural activity in the peritumoral cortex underlies the progression of tumor-associated seizures.

02-12-2025

Journal of cancer survivorship : research and practice

Health-related conditions among long-term cancer survivors diagnosed in adolescence and young adulthood (AYA): results of the SURVAYA study.

Therapeutic drug monitoring

Therapeutic Drug Monitoring of Oral Targeted Anticancer Drugs: Achievements, Experiences, Challenges, and the Path Forward.

JAMA network open

Development of a Health-Related Quality of Life Tool for Adolescents and Young Adults With Cancer.

Nature medicine

Neoadjuvant ipilimumab and nivolumab in resectable cutaneous squamous cell carcinoma: a randomized phase 2 trial.

Key Publication

Neoplasia (New York, N.Y.)

Cholesterol biosynthesis as a drug-induced vulnerability in diffuse large B cell lymphoma insensitive to EZH2 inhibition.

JAMA network open

Economic Evaluation of Comprehensive Genomic Profiling in an Advanced Solid Cancer Population.