Publications

Journal of pharmacokinetics and pharmacodynamics

A semi-physiological population pharmacokinetic model describing the non-linear disposition of indisulam.

Clinical cancer research : an official journal of the American Association for Cancer Research

Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel.

Die Pharmazie

Pharmaceutical development, quality control, stability and compatibility of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum antineoplastic agent AP5346.

Medical physics

Clinical experience with EPID dosimetry for prostate IMRT pre-treatment dose verification.

Oncogene

Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.

25-09-2006

Nederlands tijdschrift voor geneeskunde

[Defining trials of medicinal products according to the revised Dutch Medical Research in Human Subjects Act (WMO)].

23-09-2006

Current biology : CB

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

19-09-2006

British journal of cancer

A novel self-microemulsifying formulation of paclitaxel for oral administration to patients with advanced cancer.

18-09-2006

Nature genetics

Characterization of the Drosophila melanogaster genome at the nuclear lamina.

Nature methods

shRNA libraries and their use in cancer genetics.

Journal of cellular physiology

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

Journal of mass spectrometry : JMS

Sensitive inductively coupled plasma mass spectrometry assay for the determination of platinum originating from cisplatin, carboplatin, and oxaliplatin in human plasma ultrafiltrate.

Methods in enzymology

DamID: mapping of in vivo protein-genome interactions using tethered DNA adenine methyltransferase.

30-08-2006

International journal of cancer

Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT).

15-08-2006

Proceedings of the National Academy of Sciences of the United States of America

Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster.

08-08-2006

The Journal of biological chemistry

A functional genetic screen identifies TFE3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growth factor-beta.

04-08-2006

Blood

Targeting self-antigens through allogeneic TCR gene transfer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy.

Cancer treatment reviews

Future opportunities in preventing cisplatin induced ototoxicity.

Basic & clinical pharmacology & toxicology

Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Phase I and pharmacokinetic study of combined treatment with perifosine and radiation in patients with advanced solid tumours.

Nature cell biology

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.

Genes & development

TXR1-mediated thrombospondin repression: a novel mechanism of resistance to taxanes?

European journal of clinical pharmacology

Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers.

International journal of radiation oncology, biology, physics

Mid-ventilation CT scan construction from four-dimensional respiration-correlated CT scans for radiotherapy planning of lung cancer patients.

European journal of nuclear medicine and molecular imaging

Mapping of treatment-induced apoptosis in normal structures: 99mTc-Hynic-rh-annexin V SPECT and CT image fusion.

European journal of cancer (Oxford, England : 1990)

Translation and validation of the EORTC QLQ-C30 for use among Turkish and Moroccan ethnic minority cancer patients in the Netherlands.

Expert review of neurotherapeutics

Blood-brain barrier and chemotherapeutic treatment of brain tumors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

The impact of hormone replacement therapy on menopausal symptoms in younger high-risk women after prophylactic salpingo-oophorectomy.

Cold Spring Harbor symposia on quantitative biology

Genotype-phenotype relationships in a mouse model for human small-cell lung cancer.

28-07-2006

Journal of immunology (Baltimore, Md. : 1950)

Generation of T cell help through a MHC class I-restricted TCR.

15-07-2006

Blood

Gimap4 accelerates T-cell death.

15-07-2006

BMC cancer

Clinical management of women with metastatic breast cancer: a descriptive study according to age group.

06-07-2006

The British journal of dermatology

An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis.

Trends in cell biology

Current insights into the formation and breakdown of hemidesmosomes.

Cell cycle (Georgetown, Tex.)

Immense promises for tiny molecules: uncovering miRNA functions.

British journal of clinical pharmacology

Determinants of the elimination of methotrexate and 7-hydroxy-methotrexate following high-dose infusional therapy to cancer patients.

Molecular and cellular biology

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.

Medical physics

Comparison of ghosting effects for three commercial a-Si EPIDs.

The Journal of pharmacology and experimental therapeutics

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

Cell

Cross-species oncogenomics in cancer gene identification.

30-06-2006

Molecular diagnosis & therapy

Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.

15-06-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Dose-finding phase I clinical and pharmacokinetic study of orally administered irinotecan in patients with advanced solid tumors.

15-06-2006

The EMBO journal

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.

07-06-2006

Drug metabolism and disposition: the biological fate of chemicals

Saturable binding of indisulam to plasma proteins and distribution to human erythrocytes.

The oncologist

Symptoms and treatment in cancer therapy-induced early menopause.

Human immunology

Control of peripheral T cell survival: a delicate division of labor between cytokines and costimulatory molecules.

International immunology

Constitutive expression of the pre-TCR enables development of mature T cells.

Cell cycle (Georgetown, Tex.)

Controlling stem cell proliferation: CKIs at work.