Publications

Nature reviews. Cancer

Paradoxical roles of the immune system during cancer development.

EMBO reports

Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody.

Nature reviews. Cancer

KLF4, p21 and context-dependent opposing forces in cancer.

Biomedical chromatography : BMC

A simple and sensitive assay for the quantitative analysis of paclitaxel and metabolites in human plasma using liquid chromatography/tandem mass spectrometry.

Die Pharmazie

Compatibility and stability of the novel anticancer agent ES-285 x HCl formulated with 2-hydroxypropyl-beta-cyclodextrin in infusion devices.

Trends in pharmacological sciences

Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs.

Trends in pharmacological sciences

The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins.

Nucleic acids research

Human and mouse oligonucleotide-based array CGH

16-12-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients.

10-12-2005

Nucleic acids research

Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA.

09-12-2005

The Journal of cell biology

The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.

05-12-2005

The Journal of cell biology

Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin.

05-12-2005

Cell

A genomic and functional inventory of deubiquitinating enzymes.

02-12-2005

Cellular and molecular life sciences : CMLS

Dissection of cytotoxic and helper T cell responses.

Therapeutic drug monitoring

Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.

PDA journal of pharmaceutical science and technology

Pharmaceutical development of a parenteral lyophilised dosage form for the novel anticancer agent C1311.

Molecular and cellular biology

Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1.

Trends in pharmacological sciences

An emerging role for PtdIns(4,5)P2-mediated signalling in human disease.

Cancer cell

Mitogen requirement for cell cycle progression in the absence of pocket protein activity.

Current gene therapy

Prospects and limitations of T cell receptor gene therapy.

Cell cycle (Georgetown, Tex.)

CDK-dependent stabilization of Cdc6: linking growth and stress signals to activation of DNA replication.

British journal of cancer

Phase I and pharmacological study of the farnesyltransferase inhibitor tipifarnib (Zarnestra, R115777) in combination with gemcitabine and cisplatin in patients with advanced solid tumours.

28-11-2005

Oncogene

Retroviral insertional mutagenesis: past, present and future.

21-11-2005

Rapid communications in mass spectrometry : RCM

Simultaneous quantification of fludarabine and cyclophosphamide in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

16-11-2005

International journal of radiation oncology, biology, physics

Automatic prostate localization on cone-beam CT scans for high precision image-guided radiotherapy.

15-11-2005

Methods in enzymology

Functional annotation of deubiquitinating enzymes using RNA interference.

09-11-2005

Nature cell biology

The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene.

The Journal of pharmacology and experimental therapeutics

Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin.

European journal of cancer (Oxford, England : 1990)

Quality of life among long-term breast cancer survivors: a systematic review.

Breast cancer research and treatment

Electrophysiological correlates of information processing in breast-cancer patients treated with adjuvant chemotherapy.

Clinical pharmacokinetics

Clinical pharmacokinetics of cyclophosphamide.

20-10-2005

British journal of cancer

No common denominator for breast cancer lymph node metastasis.

17-10-2005

PDA journal of pharmaceutical science and technology

Pharmaceutical development of a parenteral lyophilised formulation of the investigational anticancer agent ES-285.HCl.

13-10-2005

Nederlands tijdschrift voor geneeskunde

[Rapid tracing of new patients with cancer through the nationwide network and registry of histo- and cytopathology in the Netherlands (PALGA) in order to freeze tumour material for molecular-epidemiological research].

Cell cycle (Georgetown, Tex.)

p16INK4a as a second effector of the telomere damage pathway.

Anti-cancer drugs

Phase I clinical and pharmacologic study of a 2-weekly administration of cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.

Cancer investigation

Modulation of oral drug bioavailability: from preclinical mechanism to therapeutic application.

Cancer chemotherapy and pharmacology

Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism.

Cancer chemotherapy and pharmacology

Absence of N-linked glycosylation does not affect plasma membrane localization of breast cancer resistance protein (BCRP/ABCG2).

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Quality-of-life effects of prophylactic salpingo-oophorectomy versus gynecologic screening among women at increased risk of hereditary ovarian cancer.

Investigational new drugs

Trabectedin (Yondelis, formerly ET-743), a mass balance study in patients with advanced cancer.