Publications

Molecular and cellular biology

Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.

Cancer immunology, immunotherapy : CII

Melanoma-specific tumor-infiltrating lymphocytes but not circulating melanoma-specific T cells may predict survival in resected advanced-stage melanoma patients.

Cellular and molecular life sciences : CMLS

The neurotrophic receptor TrkB: a drug target in anti-cancer therapy?

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy of high-dose alkylating chemotherapy in HER2/neu-negative breast cancer.

Genes & development

Chromosome-wide gene-specific targeting of the Drosophila dosage compensation complex.

Annals of oncology : official journal of the European Society for Medical Oncology

Higher long-term cancer survival rates in southeastern Netherlands using up-to-date period analysis.

Nature chemical biology

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors.

Cell

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.

24-03-2006

Journal of immunological methods

In situ visualization of antigen-specific T cells in cryopreserved human tissues.

20-03-2006

International journal of radiation oncology, biology, physics

Cause-specific mortality in long-term survivors of breast cancer: A 25-year follow-up study.

15-03-2006

World journal of gastroenterology

Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry.

14-03-2006

Proceedings of the National Academy of Sciences of the United States of America

Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.

07-03-2006

Clinical pharmacokinetics

Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer.

03-03-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Radiosensitization of squamous cell carcinoma by the alkylphospholipid perifosine in cell culture and xenografts.

01-03-2006

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The significance of one positive axillary node.

01-03-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Relationship between cisplatin administration and the development of ototoxicity.

20-02-2006

Biomedical chromatography : BMC

A rapid and simple HPLC-UV method for the determination of inhibition characteristics of farnesyl transferase inhibitors.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The prognosis of patients with local recurrence more than five years after breast conservation therapy for invasive breast carcinoma.

Medical physics

Accurate two-dimensional IMRT verification using a back-projection EPID dosimetry method.

International journal of radiation oncology, biology, physics

Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status.

Nature medicine

Design and use of conditional MHC class I ligands.

Clinical pharmacokinetics

Mass balance studies, with a focus on anticancer drugs.

25-01-2006

The EMBO journal

Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair.

25-01-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-term risk of cardiovascular disease in 5-year survivors of testicular cancer.

20-01-2006

The EMBO journal

CLIP-170 facilitates the formation of kinetochore-microtubule attachments.

11-01-2006

The Journal of biological chemistry

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

06-01-2006

Carcinogenesis

Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk.

Nature reviews. Cancer

Paradoxical roles of the immune system during cancer development.

EMBO reports

Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody.

Nature reviews. Cancer

KLF4, p21 and context-dependent opposing forces in cancer.

Biomedical chromatography : BMC

A simple and sensitive assay for the quantitative analysis of paclitaxel and metabolites in human plasma using liquid chromatography/tandem mass spectrometry.

Die Pharmazie

Compatibility and stability of the novel anticancer agent ES-285 x HCl formulated with 2-hydroxypropyl-beta-cyclodextrin in infusion devices.

Trends in pharmacological sciences

Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs.

Trends in pharmacological sciences

The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins.

Nucleic acids research

Human and mouse oligonucleotide-based array CGH

16-12-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients.

10-12-2005

Nucleic acids research

Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA.

09-12-2005

The Journal of cell biology

The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.

05-12-2005

The Journal of cell biology

Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin.

05-12-2005

Cell

A genomic and functional inventory of deubiquitinating enzymes.

02-12-2005

Cellular and molecular life sciences : CMLS

Dissection of cytotoxic and helper T cell responses.

Therapeutic drug monitoring

Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.

PDA journal of pharmaceutical science and technology

Pharmaceutical development of a parenteral lyophilised dosage form for the novel anticancer agent C1311.

Molecular and cellular biology

Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1.

Trends in pharmacological sciences

An emerging role for PtdIns(4,5)P2-mediated signalling in human disease.

Cancer cell

Mitogen requirement for cell cycle progression in the absence of pocket protein activity.

Current gene therapy

Prospects and limitations of T cell receptor gene therapy.