Publications

Bone marrow transplantation

Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy.

01-11-2002

Pharmacogenetics

Polymorphisms affecting function of the human organic cation transporter hOCT1 (SLC22A1): what are the consequences?

01-11-2002

Cancer research

Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir.

01-11-2002

Molecular biology of the cell

Dynamics of the alpha6beta4 integrin in keratinocytes.

01-11-2002

The Journal of biological chemistry

TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid.

25-10-2002

The Journal of biological chemistry

Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis.

18-10-2002

Anti-cancer drugs

Stability and compatibility of the investigational polymer-conjugated platinum anticancer agent AP 5280 in infusion systems and its hemolytic potential.

01-10-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Population pharmacokinetics of the novel anticancer agent E7070 during four phase I studies: model building and validation.

01-10-2002

Oncogene

Proviral activation of the tumor suppressor E2a contributes to T cell lymphomagenesis in EmuMyc transgenic mice.

26-09-2002

Journal of immunology (Baltimore, Md. : 1950)

Differential kinetics of antigen-specific CD4+ and CD8+ T cell responses in the regression of retrovirus-induced sarcomas.

15-09-2002

British journal of cancer

A phase I and pharmacokinetic study of MAG-CPT, a water-soluble polymer conjugate of camptothecin.

09-09-2002

Cancer cell

Stable suppression of tumorigenicity by virus-mediated RNA interference.

01-09-2002

Cancer chemotherapy and pharmacology

Extremely high exposures in an obese patient receiving high-dose cyclophosphamide, thiotepa and carboplatin.

01-09-2002

European journal of nuclear medicine and molecular imaging

Phase 1 study to identify tumour hypoxia in patients with head and neck cancer using technetium-99m BRU 59-21.

01-09-2002

Nature genetics

High-throughput retroviral tagging to identify components of specific signaling pathways in cancer.

01-09-2002

Diabetic medicine : a journal of the British Diabetic Association

Longitudinal assessment of the development of diabetic polyneuropathy and associated risk factors.

01-09-2002

Annals of oncology : official journal of the European Society for Medical Oncology

Late effects of adjuvant chemotherapy on cognitive function: a follow-up study in breast cancer patients.

01-09-2002

Nature genetics

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice.

01-09-2002

Anti-cancer drugs

An excretion balance and pharmacokinetic study of the novel anticancer agent E7070 in cancer patients.

01-09-2002

Journal of mass spectrometry : JMS

Quantitative analysis of the novel depsipeptide anticancer drug Kahalalide F in human plasma by high-performance liquid chromatography under basic conditions coupled to electrospray ionization tandem mass spectrometry.

01-09-2002

Molecular biology of the cell

Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale.

01-09-2002

Nature

A progression puzzle.

22-08-2002

Cancer research

The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.

15-08-2002

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Determination of 9-nitrocamptothecin and its metabolite 9-aminocamptothecin in human plasma using high-performance liquid chromatography with ultraviolet and fluorescence detection.

05-08-2002

European journal of cancer (Oxford, England : 1990)

Phase I and pharmacological study of daily oral administration of perifosine (D-21266) in patients with advanced solid tumours.

01-08-2002

The Journal of biological chemistry

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

19-07-2002

The EMBO journal

Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis.

15-07-2002

Oncogene

Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells.

11-07-2002

Cancer chemotherapy and pharmacology

Urinary and fecal excretion of topotecan in patients with malignant solid tumours.

01-07-2002

Cancer chemotherapy and pharmacology

A population analysis of the pharmacokinetics of Cremophor EL using nonlinear mixed-effect modelling.

01-07-2002

Nature reviews. Immunology

T-cell-receptor gene therapy.

01-07-2002

Analytical and bioanalytical chemistry

Determination of total platinum in plasma and plasma ultrafiltrate, from subjects dosed with the platinum-containing N-(2-hydroxypropyl)methacrylamide copolymer AP5280, by use of graphite-furnace Zeeman atomic-absorption spectrometry.

01-07-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

01-07-2002

Cancer cell

E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest.

01-07-2002

Nature genetics

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers.

01-07-2002

The Journal of experimental medicine

Contributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selection.

01-07-2002

Proceedings of the National Academy of Sciences of the United States of America

Specificity and affinity motifs for Grb2 SH2-ligand interactions.

25-06-2002

Methods in enzymology

Assays for gene silencing in yeast.

21-06-2002

Biochimica et biophysica acta

Polycomb repression: from cellular memory to cellular proliferation and cancer.

21-06-2002

The Journal of biological chemistry

Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.

21-06-2002

Cell

Dot1p modulates silencing in yeast by methylation of the nucleosome core.

14-06-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase I clinical and pharmacologic study of chronic oral administration of the farnesyl protein transferase inhibitor R115777 in advanced cancer.

01-06-2002

Novartis Foundation symposium

The 2.7 A structure of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor.

25-05-2002

Journal of immunology (Baltimore, Md. : 1950)

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2.

15-05-2002

Journal of immunology (Baltimore, Md. : 1950)

Optimizing the efficacy of epitope-directed DNA vaccination.

15-05-2002

European journal of drug metabolism and pharmacokinetics

Evaluation of the bioequivalence of tablets and capsules containing the novel anticancer agent R115777 (Zarnestra) in patients with advanced solid tumors.

09-05-2002

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Assessing health status and quality-of-life instruments: attributes and review criteria.

01-05-2002

Cancer cell

Senescence: a companion in chemotherapy?

01-05-2002

Trends in immunology

Adoptive transfer of T-cell immunity.

01-05-2002

Fertility and sterility

A low number of retrieved oocytes at in vitro fertilization treatment is predictive of early menopause.

01-05-2002