Publications

Journal of pharmaceutical sciences

Pharmaceutical development of a lyophilised dosage form for the investigational anticancer agent Imexon using dimethyl sulfoxide as solubilising and stabilising agent.

Drug metabolism and disposition: the biological fate of chemicals

Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2).

Molecular pharmacology

Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver.

Cancer chemotherapy and pharmacology

Significant induction of cyclophosphamide and thiotepa metabolism by phenytoin.

Pharmacological research

Hepatotoxicity and metabolism of trabectedin: a literature review.

Molecular pharmacology

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

Oncogene

Getting in and out of mitosis with Polo-like kinase-1.

18-04-2005

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice

Detection of single nucleotide polymorphisms in the ABCG2 gene in a Dutch population.

09-04-2005

Medical physics

Respiratory correlated cone beam CT.

01-04-2005

Cancer research

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients.

01-04-2005

Genes & development

Mouse models for human lung cancer.

15-03-2005

Molecular and cellular biology

Uncoupling anaphase-promoting complex/cyclosome activity from spindle assembly checkpoint control by deregulating polo-like kinase 1.

Journal of cell science

Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice.

Anti-cancer drugs

Effects of co-medicated drugs on cyclophosphamide bioactivation in human liver microsomes.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Compatibility and stability of the novel anti-cancer agent C1311 in infusion devices and its in vitro biocompatibility.

Cancer chemotherapy and pharmacology

Phase I study of an oral formulation of irinotecan administered daily for 14 days every 3 weeks in patients with advanced solid tumours.

British journal of clinical pharmacology

Population pharmacokinetics of orally administered paclitaxel formulated in Cremophor EL.

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I clinical and pharmacokinetic study of kahalalide F in patients with advanced androgen refractory prostate cancer.

The British journal of dermatology

Predictions of skin cancer incidence in the Netherlands up to 2015.

Genes & development

Frat is dispensable for canonical Wnt signaling in mammals.

15-02-2005

Hereditary cancer in clinical practice

Withdrawal from genetic counselling for cancer.

15-02-2005

Molecular cell

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.

04-02-2005

European journal of cancer (Oxford, England : 1990)

Normal values of serum S-100B predict prolonged survival for stage IV melanoma patients.

Genes & development

PR72, a novel regulator of Wnt signaling required for Naked cuticle function.

Nature medicine

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

Gastroenterology

Screening behavior of individuals at high risk for colorectal cancer.

Cancer research

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.

Nature cell biology

FoxM1 is required for execution of the mitotic programme and chromosome stability.

Clinical pharmacokinetics

Individualised cancer chemotherapy: strategies and performance of prospective studies on therapeutic drug monitoring with dose adaptation: a review.

20-01-2005

Rapid communications in mass spectrometry : RCM

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

13-01-2005

Blood

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment.

01-01-2005

Cancer chemotherapy and pharmacology

Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093).

01-01-2005

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

The insulin-like growth factor system in cancer prevention: potential of dietary intervention strategies.

01-01-2005

The Journal of biological chemistry

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

31-12-2004

Current biology : CB

Significant role for p16INK4a in p53-independent telomere-directed senescence.

29-12-2004

Nederlands tijdschrift voor geneeskunde

[New insights in the adjuvant treatment of gastric cancer].

18-12-2004

Mass spectrometry reviews

Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.

16-12-2004

Methods in molecular medicine

Gene transfer of MHC-restricted receptors.

09-12-2004

Methods in molecular biology (Clifton, N.J.)

Polo-like kinase-1: activity measurement and RNAi-mediated knockdown.

04-12-2004

EMBO reports

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Cancer cell death by programmed necrosis?

European journal of cancer (Oxford, England : 1990)

The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomised study.

Journal of mass spectrometry : JMS

A simple and sensitive assay for the quantitative analysis of paclitaxel in human and mouse plasma and brain tumor tissue using coupled liquid chromatography and tandem mass spectrometry.

Cancer cell

Oncogene addiction: sometimes a temporary slavery.

Acta crystallographica. Section D, Biological crystallography

Towards complete validated models in the next generation of ARP/wARP.