Publications

Genes & development

PR72, a novel regulator of Wnt signaling required for Naked cuticle function.

Nature medicine

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

Gastroenterology

Screening behavior of individuals at high risk for colorectal cancer.

Cancer research

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.

Nature cell biology

FoxM1 is required for execution of the mitotic programme and chromosome stability.

Clinical pharmacokinetics

Individualised cancer chemotherapy: strategies and performance of prospective studies on therapeutic drug monitoring with dose adaptation: a review.

20-01-2005

Rapid communications in mass spectrometry : RCM

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

13-01-2005

Blood

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment.

01-01-2005

Cancer chemotherapy and pharmacology

Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093).

01-01-2005

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

The insulin-like growth factor system in cancer prevention: potential of dietary intervention strategies.

01-01-2005

The Journal of biological chemistry

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

31-12-2004

Current biology : CB

Significant role for p16INK4a in p53-independent telomere-directed senescence.

29-12-2004

Nederlands tijdschrift voor geneeskunde

[New insights in the adjuvant treatment of gastric cancer].

18-12-2004

Mass spectrometry reviews

Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.

16-12-2004

Methods in molecular medicine

Gene transfer of MHC-restricted receptors.

09-12-2004

Methods in molecular biology (Clifton, N.J.)

Polo-like kinase-1: activity measurement and RNAi-mediated knockdown.

04-12-2004

EMBO reports

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Cancer cell death by programmed necrosis?

European journal of cancer (Oxford, England : 1990)

The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomised study.

Journal of mass spectrometry : JMS

A simple and sensitive assay for the quantitative analysis of paclitaxel in human and mouse plasma and brain tumor tissue using coupled liquid chromatography and tandem mass spectrometry.

Cancer cell

Oncogene addiction: sometimes a temporary slavery.

Acta crystallographica. Section D, Biological crystallography

Towards complete validated models in the next generation of ARP/wARP.

Rapid communications in mass spectrometry : RCM

Quantitative determination of the novel anticancer drug E7070 (indisulam) and its metabolite (1,4-benzenedisulphonamide) in human plasma, urine and faeces by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

02-11-2004

Medical physics

The long-term stability of amorphous silicon flat panel imaging devices for dosimetry purposes.

01-11-2004

Cell cycle (Georgetown, Tex.)

Checkpoint adaptation and recovery: back with Polo after the break.

01-11-2004

British journal of cancer

A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer.

18-10-2004

The Journal of biological chemistry

ATP increases the affinity between MutS ATPase domains. Implications for ATP hydrolysis and conformational changes.

15-10-2004

The Journal of experimental medicine

The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.

04-10-2004

Journal of mass spectrometry : JMS

Quantitative analysis of the P-glycoprotein inhibitor Elacridar (GF120918) in human and dog plasma using liquid chromatography with tandem mass spectrometric detection.

01-10-2004

Journal of cell science

c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

01-10-2004

Genes & development

Epigenetics and cancer.

01-10-2004

Molecular cell

Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells.

10-09-2004

Clinical colorectal cancer

Topoisomerase I inhibitors in the treatment of gastrointestinal cancer: from intravenous to oral administration.

01-09-2004

Methods and findings in experimental and clinical pharmacology

Therapeutic drug monitoring of non-anticancer drugs in cancer patients.

01-09-2004

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

In vivo imaging of apoptosis by 99mTc-Annexin V scintigraphy: visual analysis in relation to treatment response.

01-09-2004

The Journal of biological chemistry

Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis.

27-08-2004

Oncogene

Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin.

26-08-2004

Nature

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB.

26-08-2004

Cell

Stem cells and cancer; the polycomb connection.

20-08-2004

Cancer research

Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions.

15-08-2004

Nucleic acids research

Structural analysis of the bipartite DNA-binding domain of Tc3 transposase bound to transposon DNA.

12-08-2004

Oncogene

Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas.

12-08-2004

Nature genetics

Mutagenic insertion and chromosome engineering resource (MICER)

Cancer treatment reviews

Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?

Investigational new drugs

Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in mice.

Cell death and differentiation

Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability.

The Lancet. Oncology

Drug interactions in oncology.