Publications

Molecular and cellular biology

Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation.

Journal of mass spectrometry : JMS

Quantitative analysis of ES-285, an investigational marine anticancer drug, in human, mouse, rat, and dog plasma using coupled liquid chromatography and tandem mass spectrometry.

Investigational new drugs

Pharmacokinetic-pharmacodynamic guided trial design in oncology.

Annual review of biophysics and biomolecular structure

Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels.

16-04-2003

Population health metrics

Estimating the prevalence of breast cancer using a disease model: data problems and trends.

14-04-2003

The Journal of biological chemistry

Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

04-04-2003

International journal of radiation oncology, biology, physics

Three-dimensional analysis of delineation errors, setup errors, and organ motion during radiotherapy of bladder cancer.

01-04-2003

Advances in cancer research

Retroviral insertional mutagenesis: tagging cancer pathways.

01-04-2003

Cancer research

Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein.

15-03-2003

British journal of cancer

The influence of tamoxifen treatment on the oestrogen receptor in metachronous contralateral breast cancer.

10-03-2003

Cell

The histone minority report: the variant shall not be silenced.

07-03-2003

Proceedings of the National Academy of Sciences of the United States of America

Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding.

04-03-2003

Proceedings of the National Academy of Sciences of the United States of America

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.

04-03-2003

Anti-cancer drugs

Metabolism of paclitaxel in mice.

01-03-2003

Nederlands tijdschrift voor geneeskunde

[From gene to disease; ataxia telangiectasia].

01-03-2003

Journal of pharmaceutical and biomedical analysis

Development of a LC method for pharmaceutical quality control of the antimetastatic ruthenium complex NAMI-A.

26-02-2003

The EMBO journal

The alternating ATPase domains of MutS control DNA mismatch repair.

03-02-2003

Anti-cancer drugs

Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway.

Therapeutic drug monitoring

High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasma.

Annals of oncology : official journal of the European Society for Medical Oncology

Weekly oral paclitaxel as first-line treatment in patients with advanced gastric cancer.

The Journal of pharmacology and experimental therapeutics

Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir.

Advanced drug delivery reviews

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21-01-2003

The Biochemical journal

Ceramide: second messenger or modulator of membrane structure and dynamics?

15-01-2003

Journal of cell science

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

15-01-2003

Biochemical pharmacology

DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatin.

15-01-2003

Journal of immunotherapy (Hagerstown, Md. : 1997)

CD8+ T cell tolerance and cancer immunotherapy.

07-01-2003

The Journal of biological chemistry

Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.

03-01-2003

Molecular and cellular biology

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.

Molecular microbiology

The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei.

Immunity

Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

Anti-cancer drugs

Pharmacokinetics of doxorubicin and cisplatin used in intraoperative hyperthermic intrathoracic chemotherapy after cytoreductive surgery for malignant pleural mesothelioma and pleural thymoma.

Trends in biotechnology

Knockdown stands up.

The Journal of cell biology

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

23-12-2002

The oncologist

Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: an overview.

20-12-2002

The New England journal of medicine

A gene-expression signature as a predictor of survival in breast cancer.

19-12-2002

JAMA

Health-related quality-of-life assessments and patient-physician communication: a randomized controlled trial.

18-12-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase II and pharmacologic study of weekly oral paclitaxel plus cyclosporine in patients with advanced non-small-cell lung cancer.

The Journal of urology

Controlling gene expression in the urothelium using transgenic mice with inducible bladder specific Cre-lox recombination.

Current opinion in cell biology

Genome-wide histone modifications: gaining specificity by preventing promiscuity.

Cancer treatment reviews

DNA-based drug interactions of cisplatin.

Current opinion in chemical biology

RNAi and related mechanisms and their potential use for therapy.

Cancer chemotherapy and pharmacology

Development of an optimal pharmacokinetic sampling schedule for rubitecan administered orally in a daily times five schedule.

Molecular pharmacology

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.