Publications

Therapeutic drug monitoring

High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasma.

Annals of oncology : official journal of the European Society for Medical Oncology

Weekly oral paclitaxel as first-line treatment in patients with advanced gastric cancer.

The Journal of pharmacology and experimental therapeutics

Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir.

Advanced drug delivery reviews

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21-01-2003

The Biochemical journal

Ceramide: second messenger or modulator of membrane structure and dynamics?

15-01-2003

Journal of cell science

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

15-01-2003

Biochemical pharmacology

DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatin.

15-01-2003

Journal of immunotherapy (Hagerstown, Md. : 1997)

CD8+ T cell tolerance and cancer immunotherapy.

07-01-2003

The Journal of biological chemistry

Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.

03-01-2003

Molecular and cellular biology

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.

Molecular microbiology

The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei.

Immunity

Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

Anti-cancer drugs

Pharmacokinetics of doxorubicin and cisplatin used in intraoperative hyperthermic intrathoracic chemotherapy after cytoreductive surgery for malignant pleural mesothelioma and pleural thymoma.

Trends in biotechnology

Knockdown stands up.

The Journal of cell biology

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

23-12-2002

The oncologist

Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: an overview.

20-12-2002

The New England journal of medicine

A gene-expression signature as a predictor of survival in breast cancer.

19-12-2002

JAMA

Health-related quality-of-life assessments and patient-physician communication: a randomized controlled trial.

18-12-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase II and pharmacologic study of weekly oral paclitaxel plus cyclosporine in patients with advanced non-small-cell lung cancer.

The Journal of urology

Controlling gene expression in the urothelium using transgenic mice with inducible bladder specific Cre-lox recombination.

Current opinion in cell biology

Genome-wide histone modifications: gaining specificity by preventing promiscuity.

Cancer treatment reviews

DNA-based drug interactions of cisplatin.

Current opinion in chemical biology

RNAi and related mechanisms and their potential use for therapy.

Cancer chemotherapy and pharmacology

Development of an optimal pharmacokinetic sampling schedule for rubitecan administered orally in a daily times five schedule.

Molecular pharmacology

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

International journal of cancer

Submicromolar doses of alkyl-lysophospholipids induce rapid internalization, but not activation, of epidermal growth factor receptor and concomitant MAPK/ERK activation in A431 cells.

International journal of radiation oncology, biology, physics

HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.

Clinical breast cancer

Cognitive dysfunction and chemotherapy: neuropsychological findings in perspective.

Proceedings of the National Academy of Sciences of the United States of America

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

26-11-2002

AIDS (London, England)

Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs.

22-11-2002

Journal of pharmaceutical and biomedical analysis

Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.

07-11-2002

International journal of pharmaceutics

Pharmaceutical development of a parenteral lyophilized formulation of the antimetastatic ruthenium complex NAMI-A.

06-11-2002

International journal of pharmaceutics

A kinetic study of the chemical stability of the antimetastatic ruthenium complex NAMI-A.

06-11-2002

Molecular and cellular biology

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

British journal of clinical pharmacology

Development and validation of limited sampling strategies for prediction of the systemic exposure to the novel anticancer agent E7070 (N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide).

Anti-cancer drugs

E7070: a novel synthetic sulfonamide targeting the cell cycle progression for the treatment of cancer.

Bone marrow transplantation

Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy.

Pharmacogenetics

Polymorphisms affecting function of the human organic cation transporter hOCT1 (SLC22A1): what are the consequences?

Cancer research

Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir.