Publications

Cancer cell

E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest.

Nature genetics

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers.

The Journal of experimental medicine

Contributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selection.

Proceedings of the National Academy of Sciences of the United States of America

Specificity and affinity motifs for Grb2 SH2-ligand interactions.

25-06-2002

Methods in enzymology

Assays for gene silencing in yeast.

21-06-2002

Biochimica et biophysica acta

Polycomb repression: from cellular memory to cellular proliferation and cancer.

21-06-2002

The Journal of biological chemistry

Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.

21-06-2002

Cell

Dot1p modulates silencing in yeast by methylation of the nucleosome core.

14-06-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase I clinical and pharmacologic study of chronic oral administration of the farnesyl protein transferase inhibitor R115777 in advanced cancer.

01-06-2002

Novartis Foundation symposium

The 2.7 A structure of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor.

25-05-2002

Journal of immunology (Baltimore, Md. : 1950)

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2.

15-05-2002

Journal of immunology (Baltimore, Md. : 1950)

Optimizing the efficacy of epitope-directed DNA vaccination.

15-05-2002

European journal of drug metabolism and pharmacokinetics

Evaluation of the bioequivalence of tablets and capsules containing the novel anticancer agent R115777 (Zarnestra) in patients with advanced solid tumors.

09-05-2002

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Assessing health status and quality-of-life instruments: attributes and review criteria.

Cancer cell

Senescence: a companion in chemotherapy?

Trends in immunology

Adoptive transfer of T-cell immunity.

Fertility and sterility

A low number of retrieved oocytes at in vitro fertilization treatment is predictive of early menopause.

Science (New York, N.Y.)

A system for stable expression of short interfering RNAs in mammalian cells.

19-04-2002

Cancer research

A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for Doxorubicin resistance.

15-04-2002

Key Publication

Cancer cell

RUNX: a trilogy of cancer genes.

Anti-cancer drugs

Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study.

Nature reviews. Cancer

Conditional mouse models of sporadic cancer.

Molecular cancer therapeutics

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

Cancer chemotherapy and pharmacology

Population pharmacokinetics of the novel anticancer agent KRN7000.

Lancet (London, England)

Hypospadias in sons of women exposed to diethylstilbestrol in utero: a cohort study.

30-03-2002

Cancer letters

Convergence of mitogenic and DNA damage signaling in the G1 phase of the cell cycle.

28-03-2002

Nederlands tijdschrift voor geneeskunde

[The concomitant use of radiotherapy and chemotherapy for the treatment of solid malignant tumors].

16-03-2002

Journal of cell science

Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo.

15-03-2002

Cancer research

Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.

15-03-2002

Genes & development

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.

15-03-2002

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Diagnosis and treatment of isolated neck metastases of adenocarcinomas.

Genes to cells : devoted to molecular & cellular mechanisms

The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling.

Annals of oncology : official journal of the European Society for Medical Oncology

Relationship between exposure and toxicity in high-dose chemotherapy with cyclophosphamide, thiotepa and carboplatin.

Cancer chemotherapy and pharmacology

Phase I and pharmacokinetic study of SPI-77, a liposomal encapsulated dosage form of cisplatin.