Publications

Analytical biochemistry

Development and validation of a method to determine the unbound paclitaxel fraction in human plasma.

The Journal of pharmacology and experimental therapeutics

Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3).

Radiation research

Identification of differentially expressed genes in mouse kidney after irradiation using microarray analysis.

Breast cancer research and treatment

Excess risk for contralateral breast cancer in CHEK2*1100delC germline mutation carriers.

Proceedings of the National Academy of Sciences of the United States of America

Gene expression profiles of primary breast tumors maintained in distant metastases.

23-12-2003

Journal of chromatography. A

Development and validation of a liquid chromatography-ultraviolet absorbance detection assay using derivatisation for the novel marine anticancer agent ES-285 x HCl [(2S,3R)-2-amino-3-octadecanol hydrochloride] and its pharmaceutical dosage form.

12-12-2003

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalysis of zosuquidar trihydrochloride (LY335979) in small volumes of human and murine plasma by ion-pairing reversed-phase high-performance liquid chromatography.

05-12-2003

Apoptosis : an international journal on programmed cell death

The anti-cancer drug etoposide can induce caspase-8 processing and apoptosis in the absence of CD95 receptor-ligand interaction.

04-12-2003

The Journal of pathology

Integrins in regulation of tissue development and function.

01-12-2003

Genomics

Quantitative comparison of cDNA-AFLP, microarrays, and GeneChip expression data in Saccharomyces cerevisiae.

01-12-2003

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Thallium-201-chloride scintigraphy in staging and monitoring radiotherapy response in follicular lymphoma patients.

01-12-2003

Genes & development

Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location.

15-11-2003

The Journal of experimental medicine

CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool.

03-11-2003

British journal of cancer

P-glycoprotein and Mrp1 collectively protect the bone marrow from vincristine-induced toxicity in vivo.

03-11-2003

Cancer research

The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice.

01-11-2003

Molecular and cellular biology

Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations.

01-11-2003

The Journal of biological chemistry

Calcium signaling regulates translocation and activation of Rac.

10-10-2003

Cancer research

The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

Nature reviews. Cancer

New tools for functional mammalian cancer genetics.

Drug development and industrial pharmacy

Pharmaceutical development of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum anticancer agent AP 5280.

Cancer cell

The tumor-suppressive functions of the human INK4A locus.

Molecular biology of the cell

Specificity of binding of the plectin actin-binding domain to beta4 integrin.

Cell cycle (Georgetown, Tex.)

The survivin/Aurora B complex: its role in coordinating tension and attachment.

25-09-2003

The Biochemical journal

Different modes of internalization of apoptotic alkyl-lysophospholipid and cell-rescuing lysophosphatidylcholine.

15-09-2003

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-term cause-specific mortality of patients treated for Hodgkin's disease.

15-09-2003

Clinical cancer research : an official journal of the American Association for Cancer Research

Randomized phase I clinical and pharmacologic study of weekly versus twice-weekly dose-intensive cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.

European journal of cancer (Oxford, England : 1990)

Improved survival of patients with rectal cancer since 1980: a population-based study.

Cancer cell

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model.

Human reproduction (Oxford, England)

Risk of benign gynaecological diseases and hormonal disorders according to responsiveness to ovarian stimulation in IVF: a follow-up study of 8714 women.

Nucleic acids research

Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substrates.

15-08-2003

Nature

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB.

14-08-2003

Acta oncologica (Stockholm, Sweden)

Psychosocial issues in cancer genetics--current status and future directions.

06-08-2003

Seminars in cancer biology

Ras interference as cancer therapy.

01-08-2003

BioTechniques

Epigenomic profiling using microarrays.

01-08-2003

Anti-cancer drugs

Yondelis (trabectedin, ET-743): the development of an anticancer agent of marine origin.

01-08-2003

PDA journal of pharmaceutical science and technology

Pharmaceutical quality control of the investigational polymer-conjugated platinum anticancer agent AP 5280.

25-07-2003

The New England journal of medicine

High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.

03-07-2003

Journal of the National Cancer Institute

Roles of radiation dose, chemotherapy, and hormonal factors in breast cancer following Hodgkin's disease.

02-07-2003

Journal of the National Cancer Institute

Potential for bias in studies on efficacy of prophylactic surgery for BRCA1 and BRCA2 mutation.

02-07-2003

The Journal of pathology

Integrins in regulation of tissue development and function.

Laboratory animals

Cannulation of the jugular vein in mice: a method for serial withdrawal of blood samples.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

High response rates and lasting remissions after low-dose involved field radiotherapy in indolent lymphomas.

Human reproduction (Oxford, England)

Increased risk of early menopausal transition and natural menopause after poor response at first IVF treatment.

Clinical cancer research : an official journal of the American Association for Cancer Research

Increased penetration of paclitaxel into the brain by inhibition of P-Glycoprotein.

Anti-cancer drugs

In vitro pharmacokinetic study of the novel anticancer agent E7070: red blood cell and plasma protein binding in human blood.

The Netherlands journal of medicine

Compassionate use programme of irinotecan in colorectal cancer patients in The Netherlands.