Publications

Cancer research

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.

01-02-2005

Nature cell biology

FoxM1 is required for execution of the mitotic programme and chromosome stability.

01-02-2005

Clinical pharmacokinetics

Individualised cancer chemotherapy: strategies and performance of prospective studies on therapeutic drug monitoring with dose adaptation: a review.

20-01-2005

Rapid communications in mass spectrometry : RCM

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

13-01-2005

Blood

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment.

01-01-2005

Cancer chemotherapy and pharmacology

Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093).

01-01-2005

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

The insulin-like growth factor system in cancer prevention: potential of dietary intervention strategies.

01-01-2005

The Journal of biological chemistry

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

31-12-2004

Current biology : CB

Significant role for p16INK4a in p53-independent telomere-directed senescence.

29-12-2004

Nederlands tijdschrift voor geneeskunde

[New insights in the adjuvant treatment of gastric cancer].

18-12-2004

Mass spectrometry reviews

Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.

16-12-2004

Methods in molecular medicine

Gene transfer of MHC-restricted receptors.

09-12-2004

Methods in molecular biology (Clifton, N.J.)

Polo-like kinase-1: activity measurement and RNAi-mediated knockdown.

04-12-2004

EMBO reports

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator.

01-12-2004

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Cancer cell death by programmed necrosis?

01-12-2004

European journal of cancer (Oxford, England : 1990)

The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomised study.

01-12-2004

Journal of mass spectrometry : JMS

A simple and sensitive assay for the quantitative analysis of paclitaxel in human and mouse plasma and brain tumor tissue using coupled liquid chromatography and tandem mass spectrometry.

01-12-2004

Cancer cell

Oncogene addiction: sometimes a temporary slavery.

01-12-2004

Acta crystallographica. Section D, Biological crystallography

Towards complete validated models in the next generation of ARP/wARP.

01-12-2004

Rapid communications in mass spectrometry : RCM

Quantitative determination of the novel anticancer drug E7070 (indisulam) and its metabolite (1,4-benzenedisulphonamide) in human plasma, urine and faeces by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

02-11-2004

Medical physics

The long-term stability of amorphous silicon flat panel imaging devices for dosimetry purposes.

01-11-2004

Cell cycle (Georgetown, Tex.)

Checkpoint adaptation and recovery: back with Polo after the break.

01-11-2004

British journal of cancer

A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer.

18-10-2004

The Journal of biological chemistry

ATP increases the affinity between MutS ATPase domains. Implications for ATP hydrolysis and conformational changes.

15-10-2004

The Journal of experimental medicine

The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.

04-10-2004

Journal of mass spectrometry : JMS

Quantitative analysis of the P-glycoprotein inhibitor Elacridar (GF120918) in human and dog plasma using liquid chromatography with tandem mass spectrometric detection.

01-10-2004

Journal of cell science

c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

01-10-2004

Genes & development

Epigenetics and cancer.

01-10-2004

Molecular cell

Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells.

10-09-2004

Clinical colorectal cancer

Topoisomerase I inhibitors in the treatment of gastrointestinal cancer: from intravenous to oral administration.

01-09-2004

Methods and findings in experimental and clinical pharmacology

Therapeutic drug monitoring of non-anticancer drugs in cancer patients.

01-09-2004

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

In vivo imaging of apoptosis by 99mTc-Annexin V scintigraphy: visual analysis in relation to treatment response.

01-09-2004

The Journal of biological chemistry

Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis.

27-08-2004

Oncogene

Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin.

26-08-2004

Nature

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB.

26-08-2004

Cell

Stem cells and cancer; the polycomb connection.

20-08-2004

Cancer research

Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions.

15-08-2004

Nucleic acids research

Structural analysis of the bipartite DNA-binding domain of Tc3 transposase bound to transposon DNA.

12-08-2004

Oncogene

Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas.

12-08-2004

Nature genetics

Mutagenic insertion and chromosome engineering resource (MICER)

01-08-2004

Cancer treatment reviews

Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?

01-08-2004

Investigational new drugs

Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in mice.

01-08-2004

Cell death and differentiation

Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability.

01-08-2004

The Lancet. Oncology

Drug interactions in oncology.

01-08-2004

British journal of cancer

Trends in the usage of adjuvant systemic therapy for breast cancer in the Netherlands and its effect on mortality.

19-07-2004

Nederlands tijdschrift voor geneeskunde

[Methods and results of in-vitro fertilisation in the Netherlands in the years 1983-1994].

17-07-2004

Clinical cancer research : an official journal of the American Association for Cancer Research

On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients.

15-07-2004

International journal of pharmaceutics

2-Hydroxypropyl-beta-cyclodextrin extracts 2-phenylphenol from silicone tubing.

08-07-2004

Nederlands tijdschrift voor geneeskunde

[Young adults with Ewing's sarcoma].

03-07-2004

The Journal of biological chemistry

Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens.

02-07-2004

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.

FoxM1 is required for execution of the mitotic programme and chromosome stability.

Individualised cancer chemotherapy: strategies and performance of prospective studies on therapeutic drug monitoring with dose adaptation: a review.

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment.

Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093).

The insulin-like growth factor system in cancer prevention: potential of dietary intervention strategies.

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

Significant role for p16INK4a in p53-independent telomere-directed senescence.

[New insights in the adjuvant treatment of gastric cancer].

Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.

Gene transfer of MHC-restricted receptors.

Polo-like kinase-1: activity measurement and RNAi-mediated knockdown.

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator.

Cancer cell death by programmed necrosis?

The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomised study.

A simple and sensitive assay for the quantitative analysis of paclitaxel in human and mouse plasma and brain tumor tissue using coupled liquid chromatography and tandem mass spectrometry.

Oncogene addiction: sometimes a temporary slavery.

Towards complete validated models in the next generation of ARP/wARP.

Quantitative determination of the novel anticancer drug E7070 (indisulam) and its metabolite (1,4-benzenedisulphonamide) in human plasma, urine and faeces by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

The long-term stability of amorphous silicon flat panel imaging devices for dosimetry purposes.

Checkpoint adaptation and recovery: back with Polo after the break.

A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer.

ATP increases the affinity between MutS ATPase domains. Implications for ATP hydrolysis and conformational changes.

The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.

Quantitative analysis of the P-glycoprotein inhibitor Elacridar (GF120918) in human and dog plasma using liquid chromatography with tandem mass spectrometric detection.

c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

Epigenetics and cancer.

Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells.

Topoisomerase I inhibitors in the treatment of gastrointestinal cancer: from intravenous to oral administration.

Therapeutic drug monitoring of non-anticancer drugs in cancer patients.

In vivo imaging of apoptosis by 99mTc-Annexin V scintigraphy: visual analysis in relation to treatment response.

Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis.

Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin.

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB.

Stem cells and cancer; the polycomb connection.

Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions.

Structural analysis of the bipartite DNA-binding domain of Tc3 transposase bound to transposon DNA.

Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas.

Mutagenic insertion and chromosome engineering resource (MICER)

Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?

Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in mice.

Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability.

Drug interactions in oncology.

Trends in the usage of adjuvant systemic therapy for breast cancer in the Netherlands and its effect on mortality.

[Methods and results of in-vitro fertilisation in the Netherlands in the years 1983-1994].

On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients.

2-Hydroxypropyl-beta-cyclodextrin extracts 2-phenylphenol from silicone tubing.

[Young adults with Ewing's sarcoma].

Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens.

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