Publications

Nature cell biology

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.

Genes & development

TXR1-mediated thrombospondin repression: a novel mechanism of resistance to taxanes?

European journal of clinical pharmacology

Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers.

International journal of radiation oncology, biology, physics

Mid-ventilation CT scan construction from four-dimensional respiration-correlated CT scans for radiotherapy planning of lung cancer patients.

European journal of nuclear medicine and molecular imaging

Mapping of treatment-induced apoptosis in normal structures: 99mTc-Hynic-rh-annexin V SPECT and CT image fusion.

European journal of cancer (Oxford, England : 1990)

Translation and validation of the EORTC QLQ-C30 for use among Turkish and Moroccan ethnic minority cancer patients in the Netherlands.

Expert review of neurotherapeutics

Blood-brain barrier and chemotherapeutic treatment of brain tumors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

The impact of hormone replacement therapy on menopausal symptoms in younger high-risk women after prophylactic salpingo-oophorectomy.

Cold Spring Harbor symposia on quantitative biology

Genotype-phenotype relationships in a mouse model for human small-cell lung cancer.

28-07-2006

Journal of immunology (Baltimore, Md. : 1950)

Generation of T cell help through a MHC class I-restricted TCR.

15-07-2006

Blood

Gimap4 accelerates T-cell death.

15-07-2006

BMC cancer

Clinical management of women with metastatic breast cancer: a descriptive study according to age group.

06-07-2006

The British journal of dermatology

An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis.

Trends in cell biology

Current insights into the formation and breakdown of hemidesmosomes.

Cell cycle (Georgetown, Tex.)

Immense promises for tiny molecules: uncovering miRNA functions.

British journal of clinical pharmacology

Determinants of the elimination of methotrexate and 7-hydroxy-methotrexate following high-dose infusional therapy to cancer patients.

Molecular and cellular biology

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.

Medical physics

Comparison of ghosting effects for three commercial a-Si EPIDs.

The Journal of pharmacology and experimental therapeutics

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

Cell

Cross-species oncogenomics in cancer gene identification.

30-06-2006

Molecular diagnosis & therapy

Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.

15-06-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Dose-finding phase I clinical and pharmacokinetic study of orally administered irinotecan in patients with advanced solid tumors.

15-06-2006

The EMBO journal

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.

07-06-2006

Drug metabolism and disposition: the biological fate of chemicals

Saturable binding of indisulam to plasma proteins and distribution to human erythrocytes.

The oncologist

Symptoms and treatment in cancer therapy-induced early menopause.

Human immunology

Control of peripheral T cell survival: a delicate division of labor between cytokines and costimulatory molecules.

International immunology

Constitutive expression of the pre-TCR enables development of mature T cells.

Cell cycle (Georgetown, Tex.)

Controlling stem cell proliferation: CKIs at work.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Outcome of surgical treatment of pancreatic, peri-ampullary and ampullary cancer diagnosed in the south of The Netherlands: a cancer registry based study.

Cancer chemotherapy and pharmacology

The effect of P-glycoprotein and cytochrome P450 3a on the oral bioavailability of vinorelbine in mice.

Nature genetics

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster.

Cell division

Restriction beyond the restriction point: mitogen requirement for G2 passage.

18-05-2006

British journal of cancer

High exposures to bioactivated cyclophosphamide are related to the occurrence of veno-occlusive disease of the liver following high-dose chemotherapy.

08-05-2006

FASEB journal: official publication of the Federation of American Societies for Experimental Biology

Macrophage retinoblastoma deficiency leads to enhanced atherosclerosis development in ApoE-deficient mice

Analytical biochemistry

Absolute quantification of farnesylated Ras levels in complex samples using liquid chromatography fractionation combined with tryptic digestion and electrospray tandem mass spectrometry.

Journal of immunology (Baltimore, Md. : 1950)

Immunological and antitumor effects of IL-23 as a cancer vaccine adjuvant.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Anatomy changes in radiotherapy detected using portal imaging.

European journal of clinical pharmacology

Screening for polymorphisms in the PXR gene in a Dutch population.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Increased health care utilisation among 10-year breast cancer survivors.

Trends in pharmacological sciences

Clinical proteomics: searching for better tumour markers with SELDI-TOF mass spectrometry.

Nederlands tijdschrift voor geneeskunde

[Compliance with the breast cancer guidelines in the region of the Comprehensive Cancer Centre South, 20031/'04].

29-04-2006

Contributions to microbiology

The inflammatory tumor microenvironment and its impact on cancer development.

22-04-2006

Analytical chemistry

Quantification of farnesylmethylcysteine in lysates of peripheral blood mononuclear cells using liquid chromatography coupled with electrospray tandem mass spectrometry: pharmacodynamic assay for farnesyl transferase inhibitors.

15-04-2006

Nederlands tijdschrift voor geneeskunde

[Effects and costs of adjuvant chemotherapy for operable lymph node positive breast cancer with HER2/neu overexpression].

08-04-2006

Proceedings of the National Academy of Sciences of the United States of America

PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle.

04-04-2006

Clinical breast cancer

Effects of high-dose and conventional-dose adjuvant chemotherapy on long-term cognitive sequelae in patients with breast cancer: an electrophysiologic study.

Molecular and cellular biology

Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.

Cancer immunology, immunotherapy : CII

Melanoma-specific tumor-infiltrating lymphocytes but not circulating melanoma-specific T cells may predict survival in resected advanced-stage melanoma patients.

Cellular and molecular life sciences : CMLS

The neurotrophic receptor TrkB: a drug target in anti-cancer therapy?