Publications

Nature genetics

Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C).

Clinical cancer research : an official journal of the American Association for Cancer Research

Flat dosing of carboplatin is justified in adult patients with normal renal function.

European journal of cancer (Oxford, England : 1990)

Better quality of life among 10-15 year survivors of Hodgkin's lymphoma compared to 5-9 year survivors: a population-based study.

European journal of cancer (Oxford, England : 1990)

Elderly patients with rectal cancer have a higher risk of treatment-related complications and a poorer prognosis than younger patients: a population-based study.

Cancer cell

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

European journal of cancer (Oxford, England : 1990)

Translation and validation of the SF-36 Health Survey for use among Turkish and Moroccan ethnic minority cancer patients in The Netherlands.

Nature reviews. Cancer

Polycomb silencers control cell fate, development and cancer.

Breast cancer research : BCR

Predicting a local recurrence after breast-conserving therapy by gene expression profiling.

31-10-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics.

15-10-2006

British journal of cancer

Phase II and pharmacological study of oral paclitaxel (Paxoral) plus ciclosporin in anthracycline-pretreated metastatic breast cancer.

09-10-2006

The Journal of cell biology

Kidney failure in mice lacking the tetraspanin CD151.

09-10-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical and pharmacologic study of the farnesyltransferase inhibitor tipifarnib in cancer patients with normal or mildly or moderately impaired hepatic function.

Journal of pharmacokinetics and pharmacodynamics

A semi-physiological population pharmacokinetic model describing the non-linear disposition of indisulam.

Clinical cancer research : an official journal of the American Association for Cancer Research

Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel.

Die Pharmazie

Pharmaceutical development, quality control, stability and compatibility of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum antineoplastic agent AP5346.

Medical physics

Clinical experience with EPID dosimetry for prostate IMRT pre-treatment dose verification.

Oncogene

Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.

25-09-2006

Nederlands tijdschrift voor geneeskunde

[Defining trials of medicinal products according to the revised Dutch Medical Research in Human Subjects Act (WMO)].

23-09-2006

Current biology : CB

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

19-09-2006

British journal of cancer

A novel self-microemulsifying formulation of paclitaxel for oral administration to patients with advanced cancer.

18-09-2006

Nature genetics

Characterization of the Drosophila melanogaster genome at the nuclear lamina.

Nature methods

shRNA libraries and their use in cancer genetics.

Journal of cellular physiology

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

Journal of mass spectrometry : JMS

Sensitive inductively coupled plasma mass spectrometry assay for the determination of platinum originating from cisplatin, carboplatin, and oxaliplatin in human plasma ultrafiltrate.

Methods in enzymology

DamID: mapping of in vivo protein-genome interactions using tethered DNA adenine methyltransferase.

30-08-2006

International journal of cancer

Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT).

15-08-2006

Proceedings of the National Academy of Sciences of the United States of America

Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster.

08-08-2006

The Journal of biological chemistry

A functional genetic screen identifies TFE3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growth factor-beta.

04-08-2006

Blood

Targeting self-antigens through allogeneic TCR gene transfer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy.

Cancer treatment reviews

Future opportunities in preventing cisplatin induced ototoxicity.

Basic & clinical pharmacology & toxicology

Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Phase I and pharmacokinetic study of combined treatment with perifosine and radiation in patients with advanced solid tumours.

Nature cell biology

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.

Genes & development

TXR1-mediated thrombospondin repression: a novel mechanism of resistance to taxanes?

European journal of clinical pharmacology

Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers.

International journal of radiation oncology, biology, physics

Mid-ventilation CT scan construction from four-dimensional respiration-correlated CT scans for radiotherapy planning of lung cancer patients.

European journal of nuclear medicine and molecular imaging

Mapping of treatment-induced apoptosis in normal structures: 99mTc-Hynic-rh-annexin V SPECT and CT image fusion.

European journal of cancer (Oxford, England : 1990)

Translation and validation of the EORTC QLQ-C30 for use among Turkish and Moroccan ethnic minority cancer patients in the Netherlands.

Expert review of neurotherapeutics

Blood-brain barrier and chemotherapeutic treatment of brain tumors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

The impact of hormone replacement therapy on menopausal symptoms in younger high-risk women after prophylactic salpingo-oophorectomy.

Cold Spring Harbor symposia on quantitative biology

Genotype-phenotype relationships in a mouse model for human small-cell lung cancer.

28-07-2006

Journal of immunology (Baltimore, Md. : 1950)

Generation of T cell help through a MHC class I-restricted TCR.

15-07-2006

Blood

Gimap4 accelerates T-cell death.

15-07-2006

BMC cancer

Clinical management of women with metastatic breast cancer: a descriptive study according to age group.

06-07-2006

The British journal of dermatology

An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis.

Trends in cell biology

Current insights into the formation and breakdown of hemidesmosomes.

Cell cycle (Georgetown, Tex.)

Immense promises for tiny molecules: uncovering miRNA functions.

British journal of clinical pharmacology

Determinants of the elimination of methotrexate and 7-hydroxy-methotrexate following high-dose infusional therapy to cancer patients.