Publications

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I pharmacokinetic and pharmacodynamic study of the oral protein kinase C beta-inhibitor enzastaurin in combination with gemcitabine and cisplatin in patients with advanced cancer.

Minerva ginecologica

Effects of hormonal therapy on cognitive functioning in breast cancer patients: a review of the literature.

The oncologist

Concise review: Clinical relevance of drug drug and herb drug interactions mediated by the ABC transporter ABCB1 (MDR1, P-glycoprotein).

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I pharmacokinetic study of the safety and tolerability of lapatinib (GW572016) in combination with oxaliplatin/fluorouracil/leucovorin (FOLFOX4) in patients with solid tumors.

Breast (Edinburgh, Scotland)

Trends in the prognosis of patients with primary metastatic breast cancer diagnosed between 1975 and 2002.

International archives of occupational and environmental health

Monitoring of platinum surface contamination in seven Dutch hospital pharmacies using inductively coupled plasma mass spectrometry.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The health-related quality of life of long-term survivors of melanoma treated with isolated limb perfusion.

Molecular cancer therapeutics

A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells.

Proceedings of the National Academy of Sciences of the United States of America

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer.

17-07-2007

Proceedings of the National Academy of Sciences of the United States of America

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

17-07-2007

Journal of cell science

SUUR joins separate subsets of PcG, HP1 and B-type lamin targets in Drosophila.

15-07-2007

Nucleic acids research

Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease.

13-07-2007

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Simultaneous quantification of cyclophosphamide and its active metabolite 4-hydroxycyclophosphamide in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-MS/MS).

01-07-2007

Cancer research

Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis.

01-07-2007

Biomedical chromatography : BMC

Determination of imatinib mesylate and its main metabolite (CGP74588) in human plasma and murine specimens by ion-pairing reversed-phase high-performance liquid chromatography.

01-07-2007

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Prognostic significance of 99mTc Hynic-rh-annexin V scintigraphy during platinum-based chemotherapy in advanced lung cancer.

20-06-2007

Rapid communications in mass spectrometry : RCM

Validated assay for the simultaneous determination of the anti-cancer agent gemcitabine and its metabolite 2',2'-difluorodeoxyuridine in human plasma by high-performance liquid chromatography with tandem mass spectrometry.

20-06-2007

Cell

All roads lead to IKKepsilon.

15-06-2007

Hereditary cancer in clinical practice

Colorectal cancer in the family: psychosocial distress and social issues in the years following genetic counselling.

15-06-2007

Experimental cell research

Plakins in development and disease.

10-06-2007

The EMBO journal

Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation.

06-06-2007

Nature protocols

Detection of in vivo protein-DNA interactions using DamID in mammalian cells.

05-06-2007

The Journal of cell biology

Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate.

04-06-2007

Biochimica et biophysica acta

Classifying microRNAs in cancer: the good, the bad and the ugly.

Clinical cancer research : an official journal of the American Association for Cancer Research

A phase I, randomized, open-label, parallel-cohort, dose-finding study of elacridar (GF120918) and oral topotecan in cancer patients.

Nature genetics

MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer.

Investigational new drugs

Phase I dose-finding and pharmacokinetic trial of orally administered indibulin (D-24851) to patients with solid tumors.

American journal of physiology. Cell physiology

Breast cancer resistance protein (Bcrp1/Abcg2) is expressed in the harderian gland and mediates transport of conjugated protoporphyrin IX.

Gynecologic oncology

Trends in cervical cancer survival in Europe, 1983-1994: a population-based study.

International journal of radiation oncology, biology, physics

Kilo-voltage cone-beam computed tomography setup measurements for lung cancer patients; first clinical results and comparison with electronic portal-imaging device.

Journal of molecular biology

The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain.

18-05-2007

Cancer research

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage

15-05-2007

Cancer

The safety of breast-conserving therapy in patients with breast cancer aged < or = 40 years.

15-05-2007

Clinical cancer research : an official journal of the American Association for Cancer Research

CYP2C9 and CYP2C19 polymorphic forms are related to increased indisulam exposure and higher risk of severe hematologic toxicity.

15-05-2007

International journal of technology assessment in health care

Methodology of constructive technology assessment in health care.

12-05-2007

Journal of immunotherapy (Hagerstown, Md. : 1997)

Phase I clinical study with multiple peptide vaccines in combination with tetanus toxoid and GM-CSF in advanced-stage HLA-A*0201-positive melanoma patients.

02-05-2007

Blood

Effective graft depletion of MiHAg T-cell specificities and consequences for graft-versus-host disease.

Cancer chemotherapy and pharmacology

The effect of hydroxyurea on P-glycoprotein/BCRP-mediated transport and CYP3A metabolism of imatinib mesylate.

Molecular cancer therapeutics

Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha.

International journal of cancer

Less aggressive treatment and worse overall survival in cancer patients with diabetes: a large population based analysis.

Medical physics

A fast algorithm for gamma evaluation in 3D.

Cancer chemotherapy and pharmacology

Metabolism of trabectedin (ET-743, Yondelis) in patients with advanced cancer.