Publications

International journal of radiation oncology, biology, physics

Impact of external beam adjuvant radiotherapy on health-related quality of life for long-term survivors of endometrial adenocarcinoma: a population-based study.

01-09-2007

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study: a report from EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group.

01-09-2007

Cancer letters

Absence of lymphangiogenesis in ductal breast cancer at the primary tumor site.

28-08-2007

Nucleic acids research

Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification.

28-08-2007

Journal of health organization and management

Strategic behaviour of institutional providers in mental handicapped care in the Netherlands.

24-08-2007

Nature

p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a.

23-08-2007

Molecular pharmaceutics

Profiling proteasome activity in tissue with fluorescent probes.

22-08-2007

Advances in experimental medicine and biology

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.

19-08-2007

Blood

In vivo p53 response and immune reaction underlie highly effective low-dose radiotherapy in follicular lymphoma.

15-08-2007

International journal of cancer

Increased health care utilization among long-term cancer survivors compared to the average Dutch population: a population-based study.

15-08-2007

Journal of immunology (Baltimore, Md. : 1950)

In vivo antigen stability affects DNA vaccine immunogenicity.

15-08-2007

The EMBO journal

PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1.

08-08-2007

The EMBO journal

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation.

08-08-2007

The Journal of experimental medicine

A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification.

06-08-2007

AAPS PharmSciTech

Development of a bladder instillation of the indoloquinone anticancer agent EO-9 using tert-butyl alcohol as lyophilization vehicle.

03-08-2007

Investigational new drugs

Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry.

01-08-2007

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I pharmacokinetic and pharmacodynamic study of the oral protein kinase C beta-inhibitor enzastaurin in combination with gemcitabine and cisplatin in patients with advanced cancer.

01-08-2007

Minerva ginecologica

Effects of hormonal therapy on cognitive functioning in breast cancer patients: a review of the literature.

01-08-2007

The oncologist

Concise review: Clinical relevance of drug drug and herb drug interactions mediated by the ABC transporter ABCB1 (MDR1, P-glycoprotein).

01-08-2007

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I pharmacokinetic study of the safety and tolerability of lapatinib (GW572016) in combination with oxaliplatin/fluorouracil/leucovorin (FOLFOX4) in patients with solid tumors.

01-08-2007

Breast (Edinburgh, Scotland)

Trends in the prognosis of patients with primary metastatic breast cancer diagnosed between 1975 and 2002.

01-08-2007

International archives of occupational and environmental health

Monitoring of platinum surface contamination in seven Dutch hospital pharmacies using inductively coupled plasma mass spectrometry.

01-08-2007

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The health-related quality of life of long-term survivors of melanoma treated with isolated limb perfusion.

01-08-2007

Molecular cancer therapeutics

A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells.

01-08-2007

Proceedings of the National Academy of Sciences of the United States of America

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer.

17-07-2007

Proceedings of the National Academy of Sciences of the United States of America

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

17-07-2007

Journal of cell science

SUUR joins separate subsets of PcG, HP1 and B-type lamin targets in Drosophila.

15-07-2007

Nucleic acids research

Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease.

13-07-2007

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Simultaneous quantification of cyclophosphamide and its active metabolite 4-hydroxycyclophosphamide in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-MS/MS).

01-07-2007

Cancer research

Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis.

01-07-2007

Biomedical chromatography : BMC

Determination of imatinib mesylate and its main metabolite (CGP74588) in human plasma and murine specimens by ion-pairing reversed-phase high-performance liquid chromatography.

01-07-2007

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Prognostic significance of 99mTc Hynic-rh-annexin V scintigraphy during platinum-based chemotherapy in advanced lung cancer.

20-06-2007

Rapid communications in mass spectrometry : RCM

Validated assay for the simultaneous determination of the anti-cancer agent gemcitabine and its metabolite 2',2'-difluorodeoxyuridine in human plasma by high-performance liquid chromatography with tandem mass spectrometry.

20-06-2007

Cell

All roads lead to IKKepsilon.

15-06-2007

Hereditary cancer in clinical practice

Colorectal cancer in the family: psychosocial distress and social issues in the years following genetic counselling.

15-06-2007

Experimental cell research

Plakins in development and disease.

10-06-2007

The EMBO journal

Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation.

06-06-2007

Nature protocols

Detection of in vivo protein-DNA interactions using DamID in mammalian cells.

05-06-2007

The Journal of cell biology

Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate.

04-06-2007

Biochimica et biophysica acta

Classifying microRNAs in cancer: the good, the bad and the ugly.

01-06-2007

Clinical cancer research : an official journal of the American Association for Cancer Research

A phase I, randomized, open-label, parallel-cohort, dose-finding study of elacridar (GF120918) and oral topotecan in cancer patients.

01-06-2007

Nature genetics

MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer.

01-06-2007

Investigational new drugs

Phase I dose-finding and pharmacokinetic trial of orally administered indibulin (D-24851) to patients with solid tumors.

01-06-2007

American journal of physiology. Cell physiology

Breast cancer resistance protein (Bcrp1/Abcg2) is expressed in the harderian gland and mediates transport of conjugated protoporphyrin IX.

01-06-2007

Gynecologic oncology

Trends in cervical cancer survival in Europe, 1983-1994: a population-based study.

01-06-2007

International journal of radiation oncology, biology, physics

Kilo-voltage cone-beam computed tomography setup measurements for lung cancer patients; first clinical results and comparison with electronic portal-imaging device.

01-06-2007

Journal of molecular biology

The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain.

18-05-2007

Cancer research

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage

15-05-2007

Cancer

The safety of breast-conserving therapy in patients with breast cancer aged < or = 40 years.

15-05-2007

Clinical cancer research : an official journal of the American Association for Cancer Research

CYP2C9 and CYP2C19 polymorphic forms are related to increased indisulam exposure and higher risk of severe hematologic toxicity.

15-05-2007

Impact of external beam adjuvant radiotherapy on health-related quality of life for long-term survivors of endometrial adenocarcinoma: a population-based study.

Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study: a report from EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group.

Absence of lymphangiogenesis in ductal breast cancer at the primary tumor site.

Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification.

Strategic behaviour of institutional providers in mental handicapped care in the Netherlands.

p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a.

Profiling proteasome activity in tissue with fluorescent probes.

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.

In vivo p53 response and immune reaction underlie highly effective low-dose radiotherapy in follicular lymphoma.

Increased health care utilization among long-term cancer survivors compared to the average Dutch population: a population-based study.

In vivo antigen stability affects DNA vaccine immunogenicity.

PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1.

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation.

A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification.

Development of a bladder instillation of the indoloquinone anticancer agent EO-9 using tert-butyl alcohol as lyophilization vehicle.

Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry.

Phase I pharmacokinetic and pharmacodynamic study of the oral protein kinase C beta-inhibitor enzastaurin in combination with gemcitabine and cisplatin in patients with advanced cancer.

Effects of hormonal therapy on cognitive functioning in breast cancer patients: a review of the literature.

Concise review: Clinical relevance of drug drug and herb drug interactions mediated by the ABC transporter ABCB1 (MDR1, P-glycoprotein).

Phase I pharmacokinetic study of the safety and tolerability of lapatinib (GW572016) in combination with oxaliplatin/fluorouracil/leucovorin (FOLFOX4) in patients with solid tumors.

Trends in the prognosis of patients with primary metastatic breast cancer diagnosed between 1975 and 2002.

Monitoring of platinum surface contamination in seven Dutch hospital pharmacies using inductively coupled plasma mass spectrometry.

The health-related quality of life of long-term survivors of melanoma treated with isolated limb perfusion.

A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells.

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer.

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

SUUR joins separate subsets of PcG, HP1 and B-type lamin targets in Drosophila.

Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease.

Simultaneous quantification of cyclophosphamide and its active metabolite 4-hydroxycyclophosphamide in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-MS/MS).

Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis.

Determination of imatinib mesylate and its main metabolite (CGP74588) in human plasma and murine specimens by ion-pairing reversed-phase high-performance liquid chromatography.

Prognostic significance of 99mTc Hynic-rh-annexin V scintigraphy during platinum-based chemotherapy in advanced lung cancer.

Validated assay for the simultaneous determination of the anti-cancer agent gemcitabine and its metabolite 2',2'-difluorodeoxyuridine in human plasma by high-performance liquid chromatography with tandem mass spectrometry.

All roads lead to IKKepsilon.

Colorectal cancer in the family: psychosocial distress and social issues in the years following genetic counselling.

Plakins in development and disease.

Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation.

Detection of in vivo protein-DNA interactions using DamID in mammalian cells.

Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate.

Classifying microRNAs in cancer: the good, the bad and the ugly.

A phase I, randomized, open-label, parallel-cohort, dose-finding study of elacridar (GF120918) and oral topotecan in cancer patients.

MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer.

Phase I dose-finding and pharmacokinetic trial of orally administered indibulin (D-24851) to patients with solid tumors.

Breast cancer resistance protein (Bcrp1/Abcg2) is expressed in the harderian gland and mediates transport of conjugated protoporphyrin IX.

Trends in cervical cancer survival in Europe, 1983-1994: a population-based study.

Kilo-voltage cone-beam computed tomography setup measurements for lung cancer patients; first clinical results and comparison with electronic portal-imaging device.

The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain.

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage

The safety of breast-conserving therapy in patients with breast cancer aged < or = 40 years.

CYP2C9 and CYP2C19 polymorphic forms are related to increased indisulam exposure and higher risk of severe hematologic toxicity.

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