Publications

Cancer research

A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for Doxorubicin resistance.

15-04-2002

Cancer cell

RUNX: a trilogy of cancer genes.

01-04-2002

Anti-cancer drugs

Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study.

01-04-2002

Nature reviews. Cancer

Conditional mouse models of sporadic cancer.

01-04-2002

Molecular cancer therapeutics

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

01-04-2002

Cancer chemotherapy and pharmacology

Population pharmacokinetics of the novel anticancer agent KRN7000.

01-04-2002

Lancet (London, England)

Hypospadias in sons of women exposed to diethylstilbestrol in utero: a cohort study.

30-03-2002

Cancer letters

Convergence of mitogenic and DNA damage signaling in the G1 phase of the cell cycle.

28-03-2002

Nederlands tijdschrift voor geneeskunde

[The concomitant use of radiotherapy and chemotherapy for the treatment of solid malignant tumors].

16-03-2002

Journal of cell science

Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo.

15-03-2002

Cancer research

Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.

15-03-2002

Genes & development

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.

15-03-2002

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Diagnosis and treatment of isolated neck metastases of adenocarcinomas.

01-03-2002

Genes to cells : devoted to molecular & cellular mechanisms

The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling.

01-03-2002

Annals of oncology : official journal of the European Society for Medical Oncology

Relationship between exposure and toxicity in high-dose chemotherapy with cyclophosphamide, thiotepa and carboplatin.

01-03-2002

Cancer chemotherapy and pharmacology

Phase I and pharmacokinetic study of SPI-77, a liposomal encapsulated dosage form of cisplatin.

01-03-2002

The Journal of biological chemistry

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence.

22-02-2002

Biologicals : journal of the International Association of Biological Standardization

Circumventing T-cell tolerance to tumour antigens.

20-02-2002

Acta oncologica (Stockholm, Sweden)

Radiation nephropathy--the link between functional damage and vascular mediated inflammatory and thrombotic changes.

16-02-2002

Acta oncologica (Stockholm, Sweden)

Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.

16-02-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Role of health-related quality of life in palliative chemotherapy treatment decisions.

15-02-2002

Cancer chemotherapy and pharmacology

Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut.

01-02-2002

Nature cell biology

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

01-02-2002

Nature

Gene expression profiling predicts clinical outcome of breast cancer.

31-01-2002

The Journal of cell biology

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

21-01-2002

Journal of immunology (Baltimore, Md. : 1950)

Can the low-avidity self-specific T cell repertoire be exploited for tumor rejection?

15-01-2002

Advances in experimental medicine and biology

The roles of P-glycoprotein and MRP1 in the blood-brain and blood-cerebrospinal fluid barriers.

05-01-2002

Anti-cancer drugs

Topoisomerase I levels in white blood cells of patients with ovarian cancer treated with paclitaxel-cisplatin-topotecan in a phase I study.

01-01-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Increased risk of ischemic stroke after radiotherapy on the neck in patients younger than 60 years.

01-01-2002

European journal of cancer (Oxford, England : 1990)

The combined use of radiotherapy and chemotherapy in the treatment of solid tumours.

01-01-2002

The Journal of biological chemistry

Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).

07-12-2001

The Journal of investigative dermatology

Two different mutations in the cytoplasmic domain of the integrin beta 4 subunit in nonlethal forms of epidermolysis bullosa prevent interaction of beta 4 with plectin.

01-12-2001

Cancer chemotherapy and pharmacology

A comparison of limited sampling strategies for prediction of Ecteinascidin 743 clearance when administered as a 24-h infusion.

01-12-2001

Nature genetics

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

01-12-2001

Therapeutic drug monitoring

Validation of a therapeutic drug monitoring strategy for thiotepa in a high-dose chemotherapy regimen.

01-12-2001

British journal of cancer

The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients.

16-11-2001

Genes & development

Haplo-insufficiency? Let me count the ways.

15-11-2001

The Journal of biological chemistry

Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion.

09-11-2001

Journal of chromatography. B, Biomedical sciences and applications

High-performance liquid chromatographic analysis for the determination of a novel polymer-bound camptothecin derivative (MAG-camptothecin) and free camptothecin in human plasma.

05-11-2001

Journal of chromatography. B, Biomedical sciences and applications

Determination of cyclosporin A in human and mouse plasma by reversed-phase high-performance liquid chromatography.

05-11-2001

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Prognostic factors in transitional cell cancer of the bladder: an emerging role for Bcl-2 and p53.

01-11-2001

Biochemical Society transactions

Sphingolipids related to apoptosis from the point of view of membrane structure and topology.

01-11-2001

Human reproduction (Oxford, England)

Risk of cancer in the offspring of women who underwent ovarian stimulation for IVF.

01-11-2001

Current biology : CB

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors.

30-10-2001

Oncogene

Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene.

04-10-2001

Journal of the National Cancer Institute

Complexity of lung cancer modifiers: mapping of thirty genes and twenty-five interactions in half of the mouse genome.

03-10-2001

Nature immunology

Immunotherapy through TCR gene transfer.

01-10-2001

Journal of immunology (Baltimore, Md. : 1950)

Low-avidity self-specific T cells display a pronounced expansion defect that can be overcome by altered peptide ligands.

01-10-2001

Journal of immunology (Baltimore, Md. : 1950)

Redundancy of direct priming and cross-priming in tumor-specific CD8+ T cell responses.

01-10-2001

Acta crystallographica. Section D, Biological crystallography

ARP/wARP and molecular replacement.

01-10-2001

A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for Doxorubicin resistance.

RUNX: a trilogy of cancer genes.

Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study.

Conditional mouse models of sporadic cancer.

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

Population pharmacokinetics of the novel anticancer agent KRN7000.

Hypospadias in sons of women exposed to diethylstilbestrol in utero: a cohort study.

Convergence of mitogenic and DNA damage signaling in the G1 phase of the cell cycle.

[The concomitant use of radiotherapy and chemotherapy for the treatment of solid malignant tumors].

Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo.

Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.

Diagnosis and treatment of isolated neck metastases of adenocarcinomas.

The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling.

Relationship between exposure and toxicity in high-dose chemotherapy with cyclophosphamide, thiotepa and carboplatin.

Phase I and pharmacokinetic study of SPI-77, a liposomal encapsulated dosage form of cisplatin.

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence.

Circumventing T-cell tolerance to tumour antigens.

Radiation nephropathy--the link between functional damage and vascular mediated inflammatory and thrombotic changes.

Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.

Role of health-related quality of life in palliative chemotherapy treatment decisions.

Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut.

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

Gene expression profiling predicts clinical outcome of breast cancer.

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

Can the low-avidity self-specific T cell repertoire be exploited for tumor rejection?

The roles of P-glycoprotein and MRP1 in the blood-brain and blood-cerebrospinal fluid barriers.

Topoisomerase I levels in white blood cells of patients with ovarian cancer treated with paclitaxel-cisplatin-topotecan in a phase I study.

Increased risk of ischemic stroke after radiotherapy on the neck in patients younger than 60 years.

The combined use of radiotherapy and chemotherapy in the treatment of solid tumours.

Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).

Two different mutations in the cytoplasmic domain of the integrin beta 4 subunit in nonlethal forms of epidermolysis bullosa prevent interaction of beta 4 with plectin.

A comparison of limited sampling strategies for prediction of Ecteinascidin 743 clearance when administered as a 24-h infusion.

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

Validation of a therapeutic drug monitoring strategy for thiotepa in a high-dose chemotherapy regimen.

The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients.

Haplo-insufficiency? Let me count the ways.

Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion.

High-performance liquid chromatographic analysis for the determination of a novel polymer-bound camptothecin derivative (MAG-camptothecin) and free camptothecin in human plasma.

Determination of cyclosporin A in human and mouse plasma by reversed-phase high-performance liquid chromatography.

Prognostic factors in transitional cell cancer of the bladder: an emerging role for Bcl-2 and p53.

Sphingolipids related to apoptosis from the point of view of membrane structure and topology.

Risk of cancer in the offspring of women who underwent ovarian stimulation for IVF.

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors.

Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene.

Complexity of lung cancer modifiers: mapping of thirty genes and twenty-five interactions in half of the mouse genome.

Immunotherapy through TCR gene transfer.

Low-avidity self-specific T cells display a pronounced expansion defect that can be overcome by altered peptide ligands.

Redundancy of direct priming and cross-priming in tumor-specific CD8+ T cell responses.

ARP/wARP and molecular replacement.

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