Publications

Cancer metastasis reviews

Clinical biomarkers and imaging for radiotherapy-induced cell death.

European journal of cancer (Oxford, England : 1990)

Substantial increase in the use of adjuvant systemic treatment for early stage breast cancer reflects changes in guidelines in the period 1990-2006 in the southeastern Netherlands.

Cell cycle (Georgetown, Tex.)

Mouse models for BRCA1 associated tumorigenesis: from fundamental insights to preclinical utility.

Medical physics

Reconstruction of a time-averaged midposition CT scan for radiotherapy planning of lung cancer patients using deformable registration.

Anticancer research

Value of serum S-100B for prediction of distant relapse and survival in stage III B/C melanoma.

30-08-2008

Journal of immunology (Baltimore, Md. : 1950)

TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation.

15-08-2008

BMC genomics

Multiple actions of lysophosphatidic acid on fibroblasts revealed by transcriptional profiling.

14-08-2008

Current pharmaceutical design

Anticancer alkylphospholipids: mechanisms of action, cellular sensitivity and resistance, and clinical prospects.

12-08-2008

Molecular cell

Ubc9 sumoylation regulates SUMO target discrimination.

08-08-2008

British journal of cancer

PRAME expression and clinical outcome of breast cancer.

05-08-2008

Drug metabolism and disposition: the biological fate of chemicals

Extensive metabolism and hepatic accumulation of gemcitabine after multiple oral and intravenous administration in mice.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Severity of cardiovascular disease and health-related quality of life in men with prostate cancer: a longitudinal analysis from CaPSURE.

BJU international

Microarray gene-expression profiling to predict lymph node metastasis in penile carcinoma.

Molecular cancer therapeutics

Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple-knockout) and wild-type mice.

Psycho-oncology

Psychosocial issues in genetic testing for familial adenomatous polyposis: a review of the literature.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Pulmonary resection of colorectal metastases in patients with or without a history of hepatic metastases.

Molecular cancer therapeutics

New insights into the pharmacology and cytotoxicity of gemcitabine and 2',2'-difluorodeoxyuridine.

European journal of cancer (Oxford, England : 1990)

Improved overall survival for patients with rectal cancer since 1990: the effects of TME surgery and pre-operative radiotherapy.

Antimicrobial agents and chemotherapy

Pharmacokinetics of miltefosine in Old World cutaneous leishmaniasis patients.

Cell

A PASport to cellular proliferation.

25-07-2008

Current biology : CB

Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium.

22-07-2008

Cancer research

Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer.

15-07-2008

Journal of immunology (Baltimore, Md. : 1950)

CD27 instructs CD4+ T cells to provide help for the memory CD8+ T cell response after protein immunization.

15-07-2008

International journal of radiation oncology, biology, physics

The influence of a dietary protocol on cone beam CT-guided radiotherapy for prostate cancer patients.

15-07-2008

Clinical pharmacokinetics

Population pharmacokinetics and pharmacodynamics for treatment optimization in clinical oncology.

10-07-2008

Cancer cell

Deregulating EMT and senescence: double impact by a single twist.

08-07-2008

Biomarker insights

Detection of Colorectal Cancer by Serum and Tissue Protein Profiling: A Prospective Study in a Population at Risk.

02-07-2008

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Impact of shoulder complaints after neck dissection on shoulder disability and quality of life.

01-07-2008

Anti-cancer drugs

The effects of sulfur-containing compounds and gemcitabine on the binding of cisplatin to plasma proteins and DNA determined by inductively coupled plasma mass spectrometry and high performance liquid chromatography-inductively coupled plasma mass spectrometry.

01-07-2008

Urologia internationalis

Cytokine therapy response as a selection criterion for cytoreductive nephrectomy in metastatic renal clear-cell carcinoma of intermediate prognosis. Results and conclusions from a combined analysis.

01-07-2008

Tumori

Early phase Technology Assessment of nanotechnology in oncology.

21-06-2008

British journal of cancer

Phase I pharmacokinetic and pharmacodynamic study of the prenyl transferase inhibitor AZD3409 in patients with advanced cancer.

17-06-2008

Cancer research

The chemokine receptor CXCR6 and its ligand CXCL16 are expressed in carcinomas and inhibit proliferation.

15-06-2008

Clinical cancer research : an official journal of the American Association for Cancer Research

Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

15-06-2008

Cell

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

13-06-2008

Nature

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions.

12-06-2008

Methods in molecular biology (Clifton, N.J.)

Assembly of protein complexes by coexpression in prokaryotic and eukaryotic hosts: an overview.

11-06-2008

Physics in medicine and biology

An analytical approach for optimizing the leaf design of a multi-leaf collimator in a linear accelerator.

07-06-2008

PloS one

The Polycomb protein and E3 ubiquitin ligase Ring1B harbors an IRES in its highly conserved 5' UTR.

04-06-2008

Clinical pharmacology and therapeutics

PK/PD model of indisulam and capecitabine: interaction causes excessive myelosuppression.

Molecular and cellular biology

Synthetic lethal screens identify gene silencing processes in yeast and implicate the acetylated amino terminus of Sir3 in recognition of the nucleosome core.

Nature structural & molecular biology

Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.

Pharmacogenetics and genomics

Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide.

Clinical cancer research : an official journal of the American Association for Cancer Research

Oral administration of gemcitabine in patients with refractory tumors: a clinical and pharmacologic study.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

A sensitive assay for the quantitative analysis of vinorelbine in mouse and human EDTA plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.

Proteomics. Clinical applications

Influence of variations in sample handling on SELDI-TOF MS serum protein profiles for colorectal cancer.