Publications

The Journal of biological chemistry

Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

04-04-2003

International journal of radiation oncology, biology, physics

Three-dimensional analysis of delineation errors, setup errors, and organ motion during radiotherapy of bladder cancer.

01-04-2003

Advances in cancer research

Retroviral insertional mutagenesis: tagging cancer pathways.

01-04-2003

Cancer research

Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein.

15-03-2003

British journal of cancer

The influence of tamoxifen treatment on the oestrogen receptor in metachronous contralateral breast cancer.

10-03-2003

Cell

The histone minority report: the variant shall not be silenced.

07-03-2003

Proceedings of the National Academy of Sciences of the United States of America

Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding.

04-03-2003

Proceedings of the National Academy of Sciences of the United States of America

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.

04-03-2003

Anti-cancer drugs

Metabolism of paclitaxel in mice.

01-03-2003

Nederlands tijdschrift voor geneeskunde

[From gene to disease; ataxia telangiectasia].

01-03-2003

Journal of pharmaceutical and biomedical analysis

Development of a LC method for pharmaceutical quality control of the antimetastatic ruthenium complex NAMI-A.

26-02-2003

The EMBO journal

The alternating ATPase domains of MutS control DNA mismatch repair.

03-02-2003

Anti-cancer drugs

Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway.

01-02-2003

Therapeutic drug monitoring

High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasma.

01-02-2003

Annals of oncology : official journal of the European Society for Medical Oncology

Weekly oral paclitaxel as first-line treatment in patients with advanced gastric cancer.

01-02-2003

The Journal of pharmacology and experimental therapeutics

Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir.

01-02-2003

Advanced drug delivery reviews

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21-01-2003

The Biochemical journal

Ceramide: second messenger or modulator of membrane structure and dynamics?

15-01-2003

Journal of cell science

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

15-01-2003

Biochemical pharmacology

DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatin.

15-01-2003

Journal of immunotherapy (Hagerstown, Md. : 1997)

CD8+ T cell tolerance and cancer immunotherapy.

07-01-2003

The Journal of biological chemistry

Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.

03-01-2003

Molecular and cellular biology

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.

01-01-2003

Molecular microbiology

The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei.

01-01-2003

Immunity

Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

01-01-2003

Anti-cancer drugs

Pharmacokinetics of doxorubicin and cisplatin used in intraoperative hyperthermic intrathoracic chemotherapy after cytoreductive surgery for malignant pleural mesothelioma and pleural thymoma.

01-01-2003

Trends in biotechnology

Knockdown stands up.

01-01-2003

The Journal of cell biology

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

23-12-2002

The oncologist

Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: an overview.

20-12-2002

The New England journal of medicine

A gene-expression signature as a predictor of survival in breast cancer.

19-12-2002

JAMA

Health-related quality-of-life assessments and patient-physician communication: a randomized controlled trial.

18-12-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase II and pharmacologic study of weekly oral paclitaxel plus cyclosporine in patients with advanced non-small-cell lung cancer.

01-12-2002

The Journal of urology

Controlling gene expression in the urothelium using transgenic mice with inducible bladder specific Cre-lox recombination.

01-12-2002

Current opinion in cell biology

Genome-wide histone modifications: gaining specificity by preventing promiscuity.

01-12-2002

Cancer treatment reviews

DNA-based drug interactions of cisplatin.

01-12-2002

Current opinion in chemical biology

RNAi and related mechanisms and their potential use for therapy.

01-12-2002

Cancer chemotherapy and pharmacology

Development of an optimal pharmacokinetic sampling schedule for rubitecan administered orally in a daily times five schedule.

01-12-2002

Molecular pharmacology

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

01-12-2002

International journal of cancer

Submicromolar doses of alkyl-lysophospholipids induce rapid internalization, but not activation, of epidermal growth factor receptor and concomitant MAPK/ERK activation in A431 cells.

01-12-2002

International journal of radiation oncology, biology, physics

HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.

01-12-2002

Clinical breast cancer

Cognitive dysfunction and chemotherapy: neuropsychological findings in perspective.

01-12-2002

Proceedings of the National Academy of Sciences of the United States of America

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

26-11-2002

AIDS (London, England)

Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs.

22-11-2002

Journal of pharmaceutical and biomedical analysis

Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.

07-11-2002

International journal of pharmaceutics

Pharmaceutical development of a parenteral lyophilized formulation of the antimetastatic ruthenium complex NAMI-A.

06-11-2002

International journal of pharmaceutics

A kinetic study of the chemical stability of the antimetastatic ruthenium complex NAMI-A.

06-11-2002

Molecular and cellular biology

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

01-11-2002

British journal of clinical pharmacology

Development and validation of limited sampling strategies for prediction of the systemic exposure to the novel anticancer agent E7070 (N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide).

01-11-2002

Anti-cancer drugs

E7070: a novel synthetic sulfonamide targeting the cell cycle progression for the treatment of cancer.

01-11-2002

Bone marrow transplantation

Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy.

01-11-2002