Publications

The Journal of biological chemistry

Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

27-06-2003

The EMBO journal

Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension.

16-06-2003

Nederlands tijdschrift voor geneeskunde

[Trends in the incidence and prevalence of cancer and in the survival of patients in southeastern Netherlands, 1970-1999].

07-06-2003

Medical physics

Focal spot motion of linear accelerators and its effect on portal image analysis.

01-06-2003

Therapeutic drug monitoring

Sorption of thiotepa to polyurethane catheter causes falsely elevated plasma levels.

01-06-2003

Journal of leukocyte biology

Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty.

01-06-2003

Oncogene

LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21.

29-05-2003

The Journal of biological chemistry

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells.

16-05-2003

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Serum soluble CD27, but not thymidine kinase, is an independent prognostic factor for outcome in indolent non-Hodgkin's lymphoma.

14-05-2003

Human mutation

IVS10-6T>G, an ancient ATM germline mutation linked with breast cancer.

01-05-2003

Molecular and cellular biology

Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation.

01-05-2003

Journal of mass spectrometry : JMS

Quantitative analysis of ES-285, an investigational marine anticancer drug, in human, mouse, rat, and dog plasma using coupled liquid chromatography and tandem mass spectrometry.

01-05-2003

Investigational new drugs

Pharmacokinetic-pharmacodynamic guided trial design in oncology.

01-05-2003

Annual review of biophysics and biomolecular structure

Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels.

16-04-2003

Population health metrics

Estimating the prevalence of breast cancer using a disease model: data problems and trends.

14-04-2003

The Journal of biological chemistry

Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

04-04-2003

International journal of radiation oncology, biology, physics

Three-dimensional analysis of delineation errors, setup errors, and organ motion during radiotherapy of bladder cancer.

01-04-2003

Advances in cancer research

Retroviral insertional mutagenesis: tagging cancer pathways.

01-04-2003

Cancer research

Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein.

15-03-2003

British journal of cancer

The influence of tamoxifen treatment on the oestrogen receptor in metachronous contralateral breast cancer.

10-03-2003

Cell

The histone minority report: the variant shall not be silenced.

07-03-2003

Proceedings of the National Academy of Sciences of the United States of America

Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding.

04-03-2003

Proceedings of the National Academy of Sciences of the United States of America

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.

04-03-2003

Anti-cancer drugs

Metabolism of paclitaxel in mice.

01-03-2003

Nederlands tijdschrift voor geneeskunde

[From gene to disease; ataxia telangiectasia].

01-03-2003

Journal of pharmaceutical and biomedical analysis

Development of a LC method for pharmaceutical quality control of the antimetastatic ruthenium complex NAMI-A.

26-02-2003

The EMBO journal

The alternating ATPase domains of MutS control DNA mismatch repair.

03-02-2003

Anti-cancer drugs

Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway.

01-02-2003

Therapeutic drug monitoring

High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasma.

01-02-2003

Annals of oncology : official journal of the European Society for Medical Oncology

Weekly oral paclitaxel as first-line treatment in patients with advanced gastric cancer.

01-02-2003

The Journal of pharmacology and experimental therapeutics

Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir.

01-02-2003

Advanced drug delivery reviews

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21-01-2003

The Biochemical journal

Ceramide: second messenger or modulator of membrane structure and dynamics?

15-01-2003

Journal of cell science

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

15-01-2003

Biochemical pharmacology

DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatin.

15-01-2003

Journal of immunotherapy (Hagerstown, Md. : 1997)

CD8+ T cell tolerance and cancer immunotherapy.

07-01-2003

The Journal of biological chemistry

Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.

03-01-2003

Molecular and cellular biology

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.

01-01-2003

Molecular microbiology

The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei.

01-01-2003

Immunity

Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

01-01-2003

Anti-cancer drugs

Pharmacokinetics of doxorubicin and cisplatin used in intraoperative hyperthermic intrathoracic chemotherapy after cytoreductive surgery for malignant pleural mesothelioma and pleural thymoma.

01-01-2003

Trends in biotechnology

Knockdown stands up.

01-01-2003

The Journal of cell biology

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

23-12-2002

The oncologist

Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: an overview.

20-12-2002

The New England journal of medicine

A gene-expression signature as a predictor of survival in breast cancer.

19-12-2002

JAMA

Health-related quality-of-life assessments and patient-physician communication: a randomized controlled trial.

18-12-2002

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase II and pharmacologic study of weekly oral paclitaxel plus cyclosporine in patients with advanced non-small-cell lung cancer.

01-12-2002

The Journal of urology

Controlling gene expression in the urothelium using transgenic mice with inducible bladder specific Cre-lox recombination.

01-12-2002

Current opinion in cell biology

Genome-wide histone modifications: gaining specificity by preventing promiscuity.

01-12-2002

Cancer treatment reviews

DNA-based drug interactions of cisplatin.

01-12-2002