Publications

Psychology & health

Well-being, posttraumatic growth and benefit finding in long-term breast cancer survivors.

Psycho-oncology

The influence of priming and pre-existing knowledge of chemotherapy-associated cognitive complaints on the reporting of such complaints in breast cancer patients.

International journal of radiation oncology, biology, physics

Frameless stereotactic body radiotherapy for lung cancer using four-dimensional cone beam CT guidance.

Molecular interventions

Pharmacokinetic assessment of multiple ATP-binding cassette transporters: the power of combination knockout mice.

Nature

Bmi1 regulates mitochondrial function and the DNA damage response pathway.

21-05-2009

Blood

Costimulatory ligand CD70 allows induction of CD8+ T-cell immunity by immature dendritic cells in a vaccination setting.

21-05-2009

PloS one

SUMOylation of DRIL1 directs its transcriptional activity towards leukocyte lineage-specific genes.

14-05-2009

Clinical chemistry and laboratory medicine

Influence of sample storage duration on serum protein profiles assessed by surface-enhanced laser desorption/ionisation time-of-flight mass spectrometry (SELDI-TOF MS).

07-05-2009

Molecular and cellular biology

Mutational analysis of the Sir3 BAH domain reveals multiple points of interaction with nucleosomes.

Biochimica et biophysica acta

Bmi1 deficient neural stem cells have increased integrin dependent adhesion to self-secreted matrix.

Molecular and cellular biology

Direct spatial control of Epac1 by cyclic AMP.

Clinical cancer research : an official journal of the American Association for Cancer Research

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

European journal of cancer (Oxford, England : 1990)

Obtaining 'fresh' consent for genetic research with biological samples archived 10 years ago.

Breast cancer research and treatment

Screening caused rising incidence rates of ductal carcinoma in situ of the breast.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Extensive soft tissue resection with autologous tissue closure for locally recurrent breast cancer: lasting local control and acceptable morbidity.

Trends in pharmacological sciences

How important is intestinal cytochrome P450 3A metabolism?

Journal of medicinal chemistry

Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.

23-04-2009

Methods in molecular biology (Clifton, N.J.)

High-throughput T-cell epitope discovery through MHC peptide exchange.

21-04-2009

Blood

Malignant mesothelioma after radiation treatment for Hodgkin lymphoma.

16-04-2009

JAMA

Long-term mortality in cancer patients with preexisting diabetes.

15-04-2009

Cancer research

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

15-04-2009

Journal of chromatography. A

Retention studies of 2'-2'-difluorodeoxycytidine and 2'-2'-difluorodeoxyuridine nucleosides and nucleotides on porous graphitic carbon: development of a liquid chromatography-tandem mass spectrometry method.

10-04-2009

Cancer cell

Ras and pRb: the relationship gets yet more intimate.

07-04-2009

Cancer cell

ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome.

07-04-2009

DNA repair

Structural aspects of multi-domain RING/Ubox E3 ligases in DNA repair.

05-04-2009

Cell stem cell

Recreating stem cells: a novel entrance to the fountain of youth.

03-04-2009

Cancer treatment reviews

The biological and clinical role of drug transporters at the intestinal barrier.

Current opinion in immunology

Preclinical development of T cell receptor gene therapy.

Drug metabolism and disposition: the biological fate of chemicals

Organic anion-transporting polypeptide 1B1 mediates transport of Gimatecan and BNP1350 and can be inhibited by several classic ATP-binding cassette (ABC) B1 and/or ABCG2 inhibitors.

Investigational new drugs

Application of population pharmacokinetic modeling in early clinical development of the anticancer agent E7820.

International journal of radiation oncology, biology, physics

Health-related quality of life in cervical cancer survivors: a population-based survey.

International journal of radiation oncology, biology, physics

Setup uncertainties of anatomical sub-regions in head-and-neck cancer patients after offline CBCT guidance.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The impact of postmastectomy radiotherapy on local control in patients with invasive lobular breast cancer.

Current opinion in immunology

Adoptive T cell therapy of cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Brain accumulation of dasatinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by elacridar treatment.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society

Expression of insulin-like growth factor system components in colorectal tissue and its relation with serum IGF levels.

Acta oncologica (Stockholm, Sweden)

Persistent neuropathy after treatment with cisplatin and oxaliplatin.

25-03-2009

British journal of cancer

Inter-observer variability in mammography screening and effect of type and number of readers on screening outcome.

24-03-2009

Clinical cancer research : an official journal of the American Association for Cancer Research

Combining radiotherapy with APO010 in cancer treatment.

15-03-2009

PloS one

A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway.

12-03-2009

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigenK164R mutant mice.

12-03-2009

Methods in molecular biology (Clifton, N.J.)

Generation of double-knockout embryonic stem cells.

07-03-2009

Methods in molecular biology (Clifton, N.J.)

Gene modification in embryonic stem cells by single-stranded DNA oligonucleotides.

07-03-2009

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

PXR-mediated induction of human CYP3A4 and mouse Cyp3a11 by the glucocorticoid budesonide.

02-03-2009

J Pathol.: The journal of pathology

Conditional Pten knock-out mice: a model for metastatic phaeochromocytoma

European journal of cancer (Oxford, England : 1990)

Delayed diagnosis of breast cancer in women recalled for suspicious screening mammography.

Journal of clinical pathology

Opt-out plus, the patients' choice: preferences of cancer patients concerning information and consent regimen for future research with biological samples archived in the context of treatment.

European journal of cancer (Oxford, England : 1990)

Improving the efficiency of a chemotherapy day unit: applying a business approach to oncology.

International journal of clinical pharmacology and therapeutics

Bioequivalence study of a new oral topotecan formulation, relative to the current topotecan formulation, in patients with advanced solid tumors.