Publications

Molecular pharmacology

Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to up-regulated CYP2C enzymes.

01-03-2008

Cancer cell

A conditional mouse model for malignant mesothelioma.

01-03-2008

Antimicrobial agents and chemotherapy

P-glycoprotein limits oral availability, brain penetration, and toxicity of an anionic drug, the antibiotic salinomycin.

01-03-2008

The oncologist

Prolonged versus standard gemcitabine infusion: translation of molecular pharmacology to new treatment strategy.

01-03-2008

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

ERP amplitude and latency in breast cancer survivors treated with adjuvant chemotherapy.

01-03-2008

Oncogene

Oncogenic pathways impinging on the G2-restriction point.

14-02-2008

Journal of pharmaceutical and biomedical analysis

Quantitative aspects of the analysis of the monoclonal antibody trastuzumab using high-performance liquid chromatography coupled with electrospray mass spectrometry.

13-02-2008

BMC bioinformatics

Comparison of normalisation methods for surface-enhanced laser desorption and ionisation (SELDI) time-of-flight (TOF) mass spectrometry data.

07-02-2008

Oncogene

BRAF(E600) in benign and malignant human tumours.

07-02-2008

Journal of the National Cancer Institute

Personality factors and breast cancer risk: a 13-year follow-up.

06-02-2008

Medical care

The influence of proxy perspective on patient-proxy agreement in the evaluation of health-related quality of life: an empirical study.

01-02-2008

Clinical breast cancer

Persistent neurocognitive problems after adjuvant chemotherapy for breast cancer.

01-02-2008

Nucleic acids research

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data.

01-02-2008

European journal of immunology

CD8- dendritic cells preferentially cross-present Saccharomyces cerevisiae antigens.

01-02-2008

International journal of radiation oncology, biology, physics

Variability of four-dimensional computed tomography patient models.

01-02-2008

Rapid communications in mass spectrometry : RCM

Enhanced resolution triple-quadrupole mass spectrometry for ultra-sensitive and quantitative analysis of the investigational anticancer agent EO9 (apaziquone) and its metabolite EO5a in human and dog plasma to support (pre)-clinical studies of EOquin given intravesically.

31-01-2008

Mass spectrometry reviews

The application of inductively coupled plasma mass spectrometry in clinical pharmacological oncology research.

31-01-2008

BMC medical genomics

Comparing the old and new generation SELDI-TOF MS: implications for serum protein profiling.

31-01-2008

Oncogene

Ionizing radiation modulates the TRAIL death-inducing signaling complex, allowing bypass of the mitochondrial apoptosis pathway.

24-01-2008

Experimental cell research

Investigation into the mechanism regulating MRP localization.

15-01-2008

Breast cancer research and treatment

The spectrum of ATM missense variants and their contribution to contralateral breast cancer.

01-01-2008

Leukemia research

Increased Rac activity is required for the progression of T-lymphomas induced by Pten-deficiency.

01-01-2008

The oncologist

Application of PET/CT in the development of novel anticancer drugs.

01-01-2008

Cancer cell

Targeted anticancer therapies: mouse models help uncover the mechanisms of tumor escape.

01-01-2008

International journal of radiation oncology, biology, physics

Adaptive radiotherapy for prostate cancer using kilovoltage cone-beam computed tomography: first clinical results.

01-01-2008

Anti-cancer drugs

Alkylphospholipids inhibit capillary-like endothelial tube formation in vitro: antiangiogenic properties of a new class of antitumor agents.

01-01-2008

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Brain metastases in patients with renal cell cancer receiving new targeted treatment.

01-01-2008

Nuclear medicine communications

99mTc-HYNIC-rh-annexin-V scintigraphy: visual and quantitative evaluation of early treatment-induced apoptosis to predict treatment outcome.

01-01-2008

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D in vivo dose verification of entire hypo-fractionated IMRT treatments using an EPID and cone-beam CT.

01-01-2008

Clinical medicine. Oncology

Radionuclide Imaging of Apoptosis in Malignancies: Promise and Pitfalls of Tc-Hynic-rh-Annexin V Imaging.

01-01-2008

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Modeling therapy resistance in genetically engineered mouse cancer models.

01-01-2008

Acta crystallographica. Section D, Biological crystallography

ARP/wARP and molecular replacement: the next generation.

01-01-2008

Blood

Treatment-related risk factors for premature menopause following Hodgkin lymphoma.

01-01-2008

The Journal of cell biology

Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.

31-12-2007

Cell

RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.

28-12-2007

The EMBO journal

Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila.

12-12-2007

PLoS genetics

A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRC.

01-12-2007

The Lancet. Oncology

Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER).

01-12-2007

Molecular cancer therapeutics

In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast cancer resistance protein, P-glycoprotein, and multidrug resistance protein 2.

01-12-2007

International journal of radiation oncology, biology, physics

A phase I-II study of postoperative capecitabine-based chemoradiotherapy in gastric cancer.

01-12-2007

Current opinion in structural biology

Protein-protein interactions regulate Ubl conjugation.

01-12-2007

International journal of radiation oncology, biology, physics

Strategy for online correction of rotational organ motion for intensity-modulated radiotherapy of prostate cancer.

01-12-2007

Breast (Edinburgh, Scotland)

Explanatory factors for variation in the use of breast conserving surgery and radiotherapy in the Netherlands, 1990-2001.

01-12-2007

Head & neck

Heterogeneity of gene expression profiles in head and neck cancer.

01-12-2007

International journal of radiation oncology, biology, physics

Gene expression profiling to predict outcome after chemoradiation in head and neck cancer.

01-12-2007

Nature

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.

29-11-2007

Clinical pharmacokinetics

Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: a study by the EORTC-PAMM-NDDG.

22-11-2007

Rapid communications in mass spectrometry : RCM

Development and validation of an assay for the quantitative determination of cladribine nucleotides in MDCKII cells and culture medium using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.

17-11-2007

Cell cycle (Georgetown, Tex.)

What makes tumors multidrug resistant?

15-11-2007

Blood

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

15-11-2007