Publications

Immunotherapy

Immunotherapeutic strategies: the melanoma example.

JAMA

Employment status among cancer survivors.

Nature methods

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

Medical physics

A simple backprojection algorithm for 3D in vivo EPID dosimetry of IMRT treatments.

The Journal of pathology

Mammosphere-derived gene set predicts outcome in patients with ER-positive breast cancer.

Molecular and cellular biology

A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis.

The Journal of cell biology

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning.

29-06-2009

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Relationship between age and axillary lymph node involvement in women with breast cancer.

20-06-2009

Nature protocols

A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites.

17-06-2009

Clinical cancer research : an official journal of the American Association for Cancer Research

Coadministration of ritonavir strongly enhances the apparent oral bioavailability of docetaxel in patients with solid tumors.

15-06-2009

Current pharmaceutical design

Towards understanding the role of cancer-associated inflammation in chemoresistance.

13-06-2009

Blood

The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.

11-06-2009

BMC women's health

Cognitive behavioral therapy and physical exercise for climacteric symptoms in breast cancer patients experiencing treatment-induced menopause: design of a multicenter trial.

06-06-2009

Cancer cell

Mammary tumorigenesis through LPA receptor signaling.

02-06-2009

Cancer chemotherapy and pharmacology

Carboplatin dosing in overweight and obese patients with normal renal function, does weight matter?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Radiation pneumonitis in patients treated for malignant pulmonary lesions with hypofractionated radiation therapy.

Analytical and bioanalytical chemistry

Application of dried blood spots combined with high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry for simultaneous quantification of vincristine and actinomycin-D.

Medical physics

On-the-fly motion-compensated cone-beam CT using an a priori model of the respiratory motion.

Nature reviews. Cancer

High-throughput insertional mutagenesis screens in mice to identify oncogenic networks.

Psychology & health

Well-being, posttraumatic growth and benefit finding in long-term breast cancer survivors.

Psycho-oncology

The influence of priming and pre-existing knowledge of chemotherapy-associated cognitive complaints on the reporting of such complaints in breast cancer patients.

International journal of radiation oncology, biology, physics

Frameless stereotactic body radiotherapy for lung cancer using four-dimensional cone beam CT guidance.

Molecular interventions

Pharmacokinetic assessment of multiple ATP-binding cassette transporters: the power of combination knockout mice.

Nature

Bmi1 regulates mitochondrial function and the DNA damage response pathway.

21-05-2009

Blood

Costimulatory ligand CD70 allows induction of CD8+ T-cell immunity by immature dendritic cells in a vaccination setting.

21-05-2009

PloS one

SUMOylation of DRIL1 directs its transcriptional activity towards leukocyte lineage-specific genes.

14-05-2009

Clinical chemistry and laboratory medicine

Influence of sample storage duration on serum protein profiles assessed by surface-enhanced laser desorption/ionisation time-of-flight mass spectrometry (SELDI-TOF MS).

07-05-2009

Molecular and cellular biology

Mutational analysis of the Sir3 BAH domain reveals multiple points of interaction with nucleosomes.

Biochimica et biophysica acta

Bmi1 deficient neural stem cells have increased integrin dependent adhesion to self-secreted matrix.

Molecular and cellular biology

Direct spatial control of Epac1 by cyclic AMP.

Clinical cancer research : an official journal of the American Association for Cancer Research

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

European journal of cancer (Oxford, England : 1990)

Obtaining 'fresh' consent for genetic research with biological samples archived 10 years ago.

Breast cancer research and treatment

Screening caused rising incidence rates of ductal carcinoma in situ of the breast.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Extensive soft tissue resection with autologous tissue closure for locally recurrent breast cancer: lasting local control and acceptable morbidity.

Trends in pharmacological sciences

How important is intestinal cytochrome P450 3A metabolism?

Journal of medicinal chemistry

Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.

23-04-2009

Methods in molecular biology (Clifton, N.J.)

High-throughput T-cell epitope discovery through MHC peptide exchange.

21-04-2009

Blood

Malignant mesothelioma after radiation treatment for Hodgkin lymphoma.

16-04-2009

JAMA

Long-term mortality in cancer patients with preexisting diabetes.

15-04-2009

Cancer research

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

15-04-2009

Journal of chromatography. A

Retention studies of 2'-2'-difluorodeoxycytidine and 2'-2'-difluorodeoxyuridine nucleosides and nucleotides on porous graphitic carbon: development of a liquid chromatography-tandem mass spectrometry method.

10-04-2009

Cancer cell

Ras and pRb: the relationship gets yet more intimate.

07-04-2009

Cancer cell

ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome.

07-04-2009

DNA repair

Structural aspects of multi-domain RING/Ubox E3 ligases in DNA repair.

05-04-2009

Cell stem cell

Recreating stem cells: a novel entrance to the fountain of youth.

03-04-2009

Cancer treatment reviews

The biological and clinical role of drug transporters at the intestinal barrier.

Current opinion in immunology

Preclinical development of T cell receptor gene therapy.

Drug metabolism and disposition: the biological fate of chemicals

Organic anion-transporting polypeptide 1B1 mediates transport of Gimatecan and BNP1350 and can be inhibited by several classic ATP-binding cassette (ABC) B1 and/or ABCG2 inhibitors.

Investigational new drugs

Application of population pharmacokinetic modeling in early clinical development of the anticancer agent E7820.