Publications

Biochimica et biophysica acta

Therapeutic options for triple-negative breast cancers with defective homologous recombination.

Molecular cancer therapeutics

Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.

Biomedical chromatography : BMC

The bioanalysis of vinorelbine and 4-O-deacetylvinorelbine in human and mouse plasma using high-performance liquid chromatography coupled with heated electrospray ionization tandem mass-spectrometry.

Proceedings of the National Academy of Sciences of the United States of America

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.

24-11-2009

The Journal of experimental medicine

Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.

23-11-2009

British journal of cancer

Preclinical mouse models for BRCA1-associated breast cancer.

17-11-2009

Oncology (Williston Park, N.Y.)

The multidisciplinary approach to colorectal cancer liver metastases.

15-11-2009

International journal of radiation oncology, biology, physics

Strategies for online organ motion correction for intensity-modulated radiotherapy of prostate cancer: prostate, rectum, and bladder dose effects.

15-11-2009

Cell

Transformation locked in a loop.

13-11-2009

British journal of cancer

A trial of consent procedures for future research with clinically derived biological samples.

03-11-2009

Current protocols in immunology

Generation of peptide MHC class I monomers and multimers through ligand exchange.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type.

European journal of obstetrics, gynecology, and reproductive biology

Age-specific differences in the treatment of cervical cancer in the east and the south of The Netherlands 1989-2004.

Molecular biology of the cell

Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Surgical resection of the primary tumour is associated with improved survival in patients with distant metastatic breast cancer at diagnosis.

Nucleic acids research

Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome.

The Lancet. Oncology

Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Target volume shape variation during irradiation of rectal cancer patients in supine position: comparison with prone position.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

A validated assay for the quantitative analysis of vatalanib in human EDTA plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Genome research

Repertoire and evolution of miRNA genes in four divergent nematode species.

Journal of the American Society for Mass Spectrometry

Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab.

Molecular cancer research : MCR

UNC45A confers resistance to histone deacetylase inhibitors and retinoic acid.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Simultaneous determination of AZD1152 (prodrug) and AZD1152-hydroxyquinazoline pyrazol anilide by reversed phase liquid chromatography.

Radiation oncology (London, England)

AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis.

23-10-2009

Journal of controlled release : official journal of the Controlled Release Society

DNA tattoo vaccination: effect on plasmid purity and transfection efficiency of different topoisoforms.

15-10-2009

Analytical and bioanalytical chemistry

Protein versus DNA as a marker for peripheral blood mononuclear cell counting.

Expert review of anticancer therapy

State-of-the-art lung cancer radiation therapy.

Rapid communications in mass spectrometry : RCM

Simultaneous quantification of 2',2'-difluorodeoxycytidine and 2',2'-difluorodeoxyuridine nucleosides and nucleotides in white blood cells using porous graphitic carbon chromatography coupled with tandem mass spectrometry.

Biochemical pharmacology

Insight in nAChR subtype selectivity from AChBP crystal structures.

Analytical biochemistry

The bioanalysis of trastuzumab in human serum using precipitate-enhanced ellipsometry.

Breast cancer research and treatment

Validation of 70-gene prognosis signature in node-negative breast cancer.

The FEBS journal

The miRNA-192/194 cluster regulates the Period gene family and the circadian clock.

The International journal of biological markers

Detection of breast cancer by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry tissue and serum protein profiling.

30-09-2009

Clinical cancer research : an official journal of the American Association for Cancer Research

Candidate biomarkers of response to an experimental cancer drug identified through a large-scale RNA interference genetic screen.

15-09-2009

Blood

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.

10-09-2009

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Breast cancer risk in female survivors of Hodgkin's lymphoma: lower risk after smaller radiation volumes.

10-09-2009

Human antibodies

Bioanalytical methods for the quantification of therapeutic monoclonal antibodies and their application in clinical pharmacokinetic studies.

05-09-2009

Science (New York, N.Y.)

Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient.

04-09-2009

Journal of the American Chemical Society

UV-induced ligand exchange in MHC class I protein crystals.

02-09-2009

Journal of the American Chemical Society

Class I major histocompatibility complexes loaded by a periodate trigger.

02-09-2009

The oncologist

Pharmacokinetics of gemcitabine and metabolites in a patient with double-sided nephrectomy: a case report and review of the literature.

Molecular endocrinology (Baltimore, Md.)

Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.

European journal of cancer (Oxford, England : 1990)

Towards rational axillary treatment in relation to neoadjuvant therapy in breast cancer.

European journal of cancer (Oxford, England : 1990)

Regulatory aspects of genetic research with residual human tissue: effective and efficient data coding.

Journal of cancer survivorship : research and practice

The impact of disease progression on perceived health status and quality of life of long-term cancer survivors.

European journal of cancer (Oxford, England : 1990)

Clinical relevance of the triple-negative breast cancer concept: genetic basis and clinical utility of the concept.