Publications

Molecular pharmacology

Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters.

European journal of clinical investigation

microRNAs, RNA binding proteins and cancer.

Molecular imaging and biology

Predicting early chemotherapy response with technetium-99m methoxyisobutylisonitrile SPECT/CT in advanced non-small cell lung cancer.

Nature cell biology

BRD7 is a candidate tumour suppressor gene required for p53 function.

Investigational new drugs

Dose-finding and pharmacokinetic study of orally administered indibulin (D-24851) to patients with advanced solid tumors.

European journal of cancer (Oxford, England : 1990)

Trends in incidence, treatment and survival of gastric adenocarcinoma between 1990 and 2007: a population-based study in the Netherlands.

Health and quality of life outcomes

Effects of mode of administration (MOA) on the measurement properties of the EORTC QLQ-C30: a randomized study.

30-03-2010

Cancer cell

PICS-ure this: prosenescence therapy?

16-03-2010

Urologia internationalis

Pim1 regulates androgen-dependent survival signaling in prostate cancer cells.

11-03-2010

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Effects of tamoxifen and exemestane on cognitive functioning of postmenopausal patients with breast cancer: results from the neuropsychological side study of the tamoxifen and exemestane adjuvant multinational trial.

10-03-2010

Psycho-oncology

Psychological distress and use of psychosocial support in familial adenomatous polyposis.

Oncology letters

Serum proteomics and disease-specific biomarkers of patients with advanced gastric cancer.

Cell death and differentiation

Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation.

Annals of oncology : official journal of the European Society for Medical Oncology

Postoperative chemoradiotherapy in gastric cancer--a phase I-II study of radiotherapy with dose escalation of weekly cisplatin and daily capecitabine chemotherapy.

AAPS PharmSciTech

Naked plasmid DNA formulation: effect of different disaccharides on stability after lyophilisation.

Annals of oncology : official journal of the European Society for Medical Oncology

A simple system for grading the response of breast cancer to neoadjuvant chemotherapy.

BJU international

Prostate cancer survivors who would be eligible for active surveillance but were either treated with radiotherapy or managed expectantly: comparisons on long-term quality of life and symptom burden.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Simultaneous quantification of emtricitabine and tenofovir nucleotides in peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.

Annals of surgery

Prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers: very low risk for subsequent breast cancer.

Nederlands tijdschrift voor geneeskunde

[Improved compliance with the 'Melanoma' treatment guideline].

23-02-2010

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Novel therapeutics in combination with radiotherapy to improve cancer treatment: rationale, mechanisms of action and clinical perspective.

20-02-2010

Cancer research

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan.

15-02-2010

International journal of radiation oncology, biology, physics

Radiation-associated breast tumors display a distinct gene expression profile.

Carcinogenesis

Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.

Molecular cancer therapeutics

Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation.

Genome research

Bayesian network analysis of targeting interactions in chromatin.

European journal of human genetics : EJHG

Attitudes toward genetic testing in childhood and reproductive decision-making for familial adenomatous polyposis.

Breast cancer research and treatment

The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer.

Breast (Edinburgh, Scotland)

Factors contributing to improved local control after mastectomy in patients with breast cancer aged 40 years or younger.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

First clinical experience with a multiple region of interest registration and correction method in radiotherapy of head-and-neck cancer patients.

European journal of epidemiology

Reliability of self-reported diagnostic radiation history in BRCA1/2 mutation carriers.

Investigational new drugs

Two-stage model-based clinical trial design to optimize phase I development of novel anticancer agents.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Correction strategies to manage deformations in head-and-neck radiotherapy.

Molecular oncology

Benchmarking biology research organizations using a new, dedicated tool.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D Dosimetric verification of volumetric-modulated arc therapy by portal dosimetry.

Breast cancer research and treatment

Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers.

European journal of cancer (Oxford, England : 1990)

Personality is associated with health status and impact of cancer among melanoma survivors.

Acta oto-laryngologica

No hearing loss after repeated courses of tobramycin in cystic fibrosis patients.

EMBO reports

Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing.

Cancer Research

Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach

26-01-2010

Cancer research

Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.

15-01-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients.

15-01-2010

Nederlands tijdschrift voor geneeskunde

[Secondary use of human tissue: consent and better information required].

07-01-2010

Oncogene

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.

07-01-2010

Proceedings of the National Academy of Sciences of the United States of America

Recombination-induced tag exchange to track old and new proteins.

05-01-2010

Biomedical chromatography : BMC

High-performance liquid chromatography coupled with mass spectrometry for the quantitative analysis of vinca-alkaloids in biological matrices: a concise survey from the literature.

Annals of oncology : official journal of the European Society for Medical Oncology

The impact of inter-observer variation in pathological assessment of node-negative breast cancer on clinical risk assessment and patient selection for adjuvant systemic treatment.

European journal of cancer (Oxford, England : 1990)

New opportunities for drug outcomes research in cancer patients: the linkage of the Eindhoven Cancer Registry and the PHARMO Record Linkage System.

Genes & development

Tumorigenicity of the miR-17-92 cluster distilled.