Publications

Annals of oncology : official journal of the European Society for Medical Oncology

Two-protein signature of novel serological markers apolipoprotein-A2 and serum amyloid alpha predicts prognosis in patients with metastatic renal cell cancer and improves the currently used prognostic survival models.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Staging and management of axillary lymph nodes in patients with local recurrence in the breast or chest wall after a previous negative sentinel node procedure.

Journal of tissue engineering and regenerative medicine

Dexamethasone treatment during the expansion phase maintains stemness of bone marrow mesenchymal stem cells.

Clinical cancer research : an official journal of the American Association for Cancer Research

Rapid and robust transgenic high-grade glioma mouse models for therapy intervention studies.

Oncology reports

Identification of serum proteins as prognostic and predictive markers of colorectal cancer using surface enhanced laser desorption ionization-time of flight mass spectrometry.

British journal of pharmacology

Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir.

Cancer causes & control : CCC

Cancer risk in DES daughters.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Genetic testing in Li-Fraumeni syndrome: uptake and psychosocial consequences.

20-06-2010

Human antibodies

Pharmacokinetics of rituximab in patients with CD20 positive B-cell malignancies.

18-06-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Inhibition of the PI3K pathway: hope we can believe in?

15-06-2010

The Journal of experimental medicine

One naive T cell, multiple fates in CD8+ T cell differentiation.

07-06-2010

Nature structural & molecular biology

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.

Medical physics

Catching errors with in vivo EPID dosimetry.

Journal of medical genetics

TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.

The Journal of investigative dermatology

Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles.

Current opinion in cell biology

Genome-nuclear lamina interactions and gene regulation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors.

Molecular cancer research : MCR

The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.

Molecular cell

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation.

28-05-2010

International journal of pharmaceutics

Lipopolysaccharide contamination in intradermal DNA vaccination: toxic impurity or adjuvant?

05-05-2010

Annals of surgical oncology

Metastatic potential of T1 breast cancer can be predicted by the 70-gene MammaPrint signature.

Proteins

Structure of human CLIC3 at 2 A resolution.

British journal of clinical pharmacology

Population pharmacokinetics of intravenously and orally administered docetaxel with or without co-administration of ritonavir in patients with advanced cancer.

Clinical genetics

Psychosocial impact of Von Hippel-Lindau disease: levels and sources of distress.

European journal of cancer (Oxford, England : 1990)

Cost-effectiveness of the 70-gene signature versus St. Gallen guidelines and Adjuvant Online for early breast cancer.

Cancer

Intra-arterial versus intravenous chemoradiation for advanced head and neck cancer: Results of a randomized phase 3 trial.

Nature medicine

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.

The Journal of biological chemistry

Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.

23-04-2010

BMC genomics

Major role for mRNA stability in shaping the kinetics of gene induction.

21-04-2010

Proceedings of the National Academy of Sciences of the United States of America

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.

20-04-2010

BMC genomics

Small RNA expression and strain specificity in the rat.

19-04-2010

Journal of cell science

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.

15-04-2010

Cell

Drugging drug resistance.

02-04-2010

Cell

It's diagnostics, stupid.

02-04-2010

Seminars in radiation oncology

Adaptive radiotherapy for lung cancer.

Breast cancer research and treatment

The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer.

Psycho-oncology

The impact of different definitions and reference groups on the prevalence of cognitive impairment: a study in postmenopausal breast cancer patients before the start of adjuvant systemic therapy.

Annals of surgery

MRI-model to guide the surgical treatment in breast cancer patients after neoadjuvant chemotherapy.

Molecular cancer research : MCR

Interleukin-1R-associated kinase 2 is a novel modulator of the transforming growth factor beta signaling cascade.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The role of FDG PET/CT in patients with locoregional breast cancer recurrence: a comparison to conventional imaging techniques.

Annals of oncology : official journal of the European Society for Medical Oncology

The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age.

Investigational new drugs

Disposition and toxicity of trabectedin (ET-743) in wild-type and mdr1 gene (P-gp) knock-out mice.

Molecular pharmacology

Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters.

European journal of clinical investigation

microRNAs, RNA binding proteins and cancer.

Molecular imaging and biology

Predicting early chemotherapy response with technetium-99m methoxyisobutylisonitrile SPECT/CT in advanced non-small cell lung cancer.

Nature cell biology

BRD7 is a candidate tumour suppressor gene required for p53 function.

Investigational new drugs

Dose-finding and pharmacokinetic study of orally administered indibulin (D-24851) to patients with advanced solid tumors.

European journal of cancer (Oxford, England : 1990)

Trends in incidence, treatment and survival of gastric adenocarcinoma between 1990 and 2007: a population-based study in the Netherlands.