Publications

PLoS computational biology

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

01-01-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors.

01-01-2010

The Journal of pathology

A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis.

01-01-2010

Nucleosides, nucleotides & nucleic acids

Facile small scale synthesis of nucleoside 5'-phosphate mixtures.

01-01-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide.

01-01-2010

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The use of fluorescent dyes and probes in surgical oncology.

01-01-2010

BioEssays : news and reviews in molecular, cellular and developmental biology

G protein-coupled receptors: the inside story.

01-01-2010

The Journal of clinical investigation

CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production.

01-01-2010

Clinical pharmacology and therapeutics

Intravenous-to-oral switch in anticancer chemotherapy: a focus on docetaxel and paclitaxel.

01-01-2010

Proc Natl Acad Sci U S A: Proceedings of the National Academy of Sciences of the United States of America

Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia

22-12-2009

Breast cancer research : BCR

Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients.

22-12-2009

Oncogene

Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer.

17-12-2009

Journal of the National Cancer Institute

Estrogen receptor-alpha phosphorylation at serine-118 and tamoxifen response in breast cancer.

16-12-2009

Journal of the National Cancer Institute

Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.

16-12-2009

Clinical cancer research : an official journal of the American Association for Cancer Research

ABCC2, ABCC3, and ABCB1, but not CYP3A, Protect against Trabectedin-Mediated Hepatotoxicity.

15-12-2009

The Biochemical journal

Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.

14-12-2009

Journal of pharmaceutical and biomedical analysis

The bioanalysis of the monoclonal antibody trastuzumab by high-performance liquid chromatography with fluorescence detection after immuno-affinity purification from human serum.

05-12-2009

The EMBO journal

Histone H1 binding is inhibited by histone variant H3.3.

02-12-2009

Methods in molecular biology (Clifton, N.J.)

Studying drug resistance using genetically engineered mouse models for breast cancer.

02-12-2009

Cancer research

Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.

01-12-2009

International journal of radiation oncology, biology, physics

Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy.

01-12-2009

Molecular oncology

Review on early technology assessments of nanotechnologies in oncology.

01-12-2009

Cancer treatment reviews

High-grade glioma mouse models and their applicability for preclinical testing.

01-12-2009

Biochimica et biophysica acta

Metastasis mechanisms.

01-12-2009

Drug metabolism and disposition: the biological fate of chemicals

Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam.

01-12-2009

Psycho-oncology

Long-term cancer survivors experience work changes after diagnosis: results of a population-based study.

01-12-2009

Biochimica et biophysica acta

Therapeutic options for triple-negative breast cancers with defective homologous recombination.

01-12-2009

Molecular cancer therapeutics

Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.

01-12-2009

Biomedical chromatography : BMC

The bioanalysis of vinorelbine and 4-O-deacetylvinorelbine in human and mouse plasma using high-performance liquid chromatography coupled with heated electrospray ionization tandem mass-spectrometry.

01-12-2009

Proceedings of the National Academy of Sciences of the United States of America

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.

24-11-2009

The Journal of experimental medicine

Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.

23-11-2009

British journal of cancer

Preclinical mouse models for BRCA1-associated breast cancer.

17-11-2009

Oncology (Williston Park, N.Y.)

The multidisciplinary approach to colorectal cancer liver metastases.

15-11-2009

International journal of radiation oncology, biology, physics

Strategies for online organ motion correction for intensity-modulated radiotherapy of prostate cancer: prostate, rectum, and bladder dose effects.

15-11-2009

Cell

Transformation locked in a loop.

13-11-2009

British journal of cancer

A trial of consent procedures for future research with clinically derived biological samples.

03-11-2009

Current protocols in immunology

Generation of peptide MHC class I monomers and multimers through ligand exchange.

01-11-2009

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type.

01-11-2009

European journal of obstetrics, gynecology, and reproductive biology

Age-specific differences in the treatment of cervical cancer in the east and the south of The Netherlands 1989-2004.

01-11-2009

Molecular biology of the cell

Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA.

01-11-2009

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Surgical resection of the primary tumour is associated with improved survival in patients with distant metastatic breast cancer at diagnosis.

01-11-2009

Nucleic acids research

Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome.

01-11-2009

The Lancet. Oncology

Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study.

01-11-2009

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Target volume shape variation during irradiation of rectal cancer patients in supine position: comparison with prone position.

01-11-2009

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

A validated assay for the quantitative analysis of vatalanib in human EDTA plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

01-11-2009

Genome research

Repertoire and evolution of miRNA genes in four divergent nematode species.

01-11-2009

Journal of the American Society for Mass Spectrometry

Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab.

01-11-2009

Molecular cancer research : MCR

UNC45A confers resistance to histone deacetylase inhibitors and retinoic acid.

01-11-2009

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Simultaneous determination of AZD1152 (prodrug) and AZD1152-hydroxyquinazoline pyrazol anilide by reversed phase liquid chromatography.

01-11-2009

Radiation oncology (London, England)

AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis.

23-10-2009