Publications

The Journal of clinical investigation

Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

Genes, chromosomes & cancer

Genomic profile of endometrial tumors depends on morphological subtype, not on tamoxifen exposure.

International journal of radiation oncology, biology, physics

Radiation pneumonitis after hypofractionated radiotherapy: evaluation of the LQ(L) model and different dose parameters.

European journal of nuclear medicine and molecular imaging

18F-FDG PET/CT for monitoring induction chemotherapy in patients with primary inoperable penile carcinoma: first clinical results.

Current clinical pharmacology

Abrogation of the G2 checkpoint by inhibition of Wee-1 kinase results in sensitization of p53-deficient tumor cells to DNA-damaging agents.

Cancer immunology, immunotherapy : CII

RNA interference targeting programmed death receptor-1 improves immune functions of tumor-specific T cells.

Clinical pharmacokinetics

Clinical pharmacokinetics of therapeutic monoclonal antibodies.

Current clinical pharmacology

Inducing synthetic lethality using PARP inhibitors.

Journal of pharmacokinetics and pharmacodynamics

A model of hypertension and proteinuria in cancer patients treated with the anti-angiogenic drug E7080.

Current clinical pharmacology

DNA vaccination in oncology: current status, opportunities and perspectives.

Breast cancer research and treatment

Half of breast cancer patients discontinue tamoxifen and any endocrine treatment before the end of the recommended treatment period of 5 years: a population-based analysis.

Current clinical pharmacology

Personalized medicine in oncology: a personal view with myths and facts.

Cell

NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome.

23-07-2010

International journal of radiation oncology, biology, physics

Interobserver variation of clinical target volume delineation in gastric cancer.

15-07-2010

Mass spectrometry reviews

Mass spectrometry in the quantitative analysis of therapeutic intracellular nucleotide analogs.

14-07-2010

Journal of the American Chemical Society

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

07-07-2010

Nucleic acids research

Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence.

Annals of oncology : official journal of the European Society for Medical Oncology

Two-protein signature of novel serological markers apolipoprotein-A2 and serum amyloid alpha predicts prognosis in patients with metastatic renal cell cancer and improves the currently used prognostic survival models.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Staging and management of axillary lymph nodes in patients with local recurrence in the breast or chest wall after a previous negative sentinel node procedure.

Journal of tissue engineering and regenerative medicine

Dexamethasone treatment during the expansion phase maintains stemness of bone marrow mesenchymal stem cells.

Clinical cancer research : an official journal of the American Association for Cancer Research

Rapid and robust transgenic high-grade glioma mouse models for therapy intervention studies.

Oncology reports

Identification of serum proteins as prognostic and predictive markers of colorectal cancer using surface enhanced laser desorption ionization-time of flight mass spectrometry.

British journal of pharmacology

Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir.

Cancer causes & control : CCC

Cancer risk in DES daughters.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Genetic testing in Li-Fraumeni syndrome: uptake and psychosocial consequences.

20-06-2010

Human antibodies

Pharmacokinetics of rituximab in patients with CD20 positive B-cell malignancies.

18-06-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Inhibition of the PI3K pathway: hope we can believe in?

15-06-2010

The Journal of experimental medicine

One naive T cell, multiple fates in CD8+ T cell differentiation.

07-06-2010

Nature structural & molecular biology

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.

Medical physics

Catching errors with in vivo EPID dosimetry.

Journal of medical genetics

TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.

The Journal of investigative dermatology

Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles.

Current opinion in cell biology

Genome-nuclear lamina interactions and gene regulation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors.

Molecular cancer research : MCR

The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.

Molecular cell

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation.

28-05-2010

International journal of pharmaceutics

Lipopolysaccharide contamination in intradermal DNA vaccination: toxic impurity or adjuvant?

05-05-2010

Annals of surgical oncology

Metastatic potential of T1 breast cancer can be predicted by the 70-gene MammaPrint signature.

Proteins

Structure of human CLIC3 at 2 A resolution.

British journal of clinical pharmacology

Population pharmacokinetics of intravenously and orally administered docetaxel with or without co-administration of ritonavir in patients with advanced cancer.

Clinical genetics

Psychosocial impact of Von Hippel-Lindau disease: levels and sources of distress.

European journal of cancer (Oxford, England : 1990)

Cost-effectiveness of the 70-gene signature versus St. Gallen guidelines and Adjuvant Online for early breast cancer.

Cancer

Intra-arterial versus intravenous chemoradiation for advanced head and neck cancer: Results of a randomized phase 3 trial.

Nature medicine

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.