Publications

Current clinical pharmacology

Pharmacodynamic biomarkers in model-based drug development in oncology.

Archives of dermatology

Impact of melanoma on patients' lives among 562 survivors: a Dutch population-based study.

Breast cancer research and treatment

Body weight and risk of breast cancer in BRCA1/2 mutation carriers.

Medical physics

Simplifying EPID dosimetry for IMRT treatment verification.

Nature structural & molecular biology

Structural basis of substrate discrimination and integrin binding by autotaxin.

Cell cycle (Georgetown, Tex.)

Screening for modulators of cisplatin sensitivity: unbiased screens reveal common themes.

Annals of oncology : official journal of the European Society for Medical Oncology

Clinical evaluation of AZD1152, an i.v. inhibitor of Aurora B kinase, in patients with solid malignant tumors.

Plastic and reconstructive surgery

Temporary banking of the nipple-areola complex in 97 skin-sparing mastectomies.

Psycho-oncology

Psychological distress and quality of life of partners of individuals with familial adenomatous polyposis.

Genes, chromosomes & cancer

Genomic signature of BRCA1 deficiency in sporadic basal-like breast tumors.

PloS one

Lysine residue 185 of Rad1 is a topological but not a functional counterpart of lysine residue 164 of PCNA.

31-01-2011

Journal of pharmaceutical and biomedical analysis

Determination of platinum originating from carboplatin in canine sebum and cerumen by inductively coupled plasma mass spectrometry.

25-01-2011

Chembiochem : a European journal of chemical biology

A modified epigenetics toolbox to study histone modifications on the nucleosome core.

24-01-2011

Clinical cancer research : an official journal of the American Association for Cancer Research

High impact of Oatp1a/1b transporters on in vivo disposition of the hydrophobic anticancer drug paclitaxel.

15-01-2011

BMC cancer

Behavioral and psychosocial effects of rapid genetic counseling and testing in newly diagnosed breast cancer patients: design of a multicenter randomized clinical trial.

10-01-2011

Cold Spring Harbor symposia on quantitative biology

Role of the nuclear lamina in genome organization and gene expression.

07-01-2011

Annals of the New York Academy of Sciences

The descent of memory T cells.

Computer methods and programs in biomedicine

Piraña and PCluster: a modeling environment and cluster infrastructure for NONMEM.

Cancer chemotherapy and pharmacology

Characterization of the in vitro activity of AZD3409, a novel prenyl transferase inhibitor.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Enriching lipid nanovesicles with short-chain glucosylceramide improves doxorubicin delivery and efficacy in solid tumors.

Nature cell biology

TSPYL5 suppresses p53 levels and function by physical interaction with USP7.

Breast cancer research and treatment

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer.

European journal of cancer (Oxford, England : 1990)

Psychometric validation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Endometrial Cancer Module (EORTC QLQ-EN24).

PloS one

The Fanconi anemia core complex is dispensable during somatic hypermutation and class switch recombination.

29-12-2010

Angewandte Chemie (International ed. in English)

Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin.

27-12-2010

Analytica chimica acta

Bioanalytical methods for determination of tamoxifen and its phase I metabolites: a review.

17-12-2010

Cell cycle (Georgetown, Tex.)

Do predictive signatures really predict response to cancer chemotherapy?

15-12-2010

Cancer research

Twenty-second annual Pezcoller Symposium: RNA biology and cancer.

15-12-2010

International journal of cancer

Individual and combined roles of CYP3A, P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) in the pharmacokinetics of docetaxel.

15-12-2010

British journal of cancer

Identification of a low-risk subgroup of HER-2-positive breast cancer by the 70-gene prognosis signature.

07-12-2010

BMC cancer

Design of the Physical exercise during Adjuvant Chemotherapy Effectiveness Study (PACES): a randomized controlled trial to evaluate effectiveness and cost-effectiveness of physical exercise in improving physical fitness and reducing fatigue.

07-12-2010

Nanotechnology

(Non-targeted) radioactive/fluorescent nanoparticles and their potential in combined pre- and intraoperative imaging during sentinel lymph node resection.

03-12-2010

Nederlands tijdschrift voor geneeskunde

[Long-term complications following treatment of testicular cancer and Hodgkin lymphoma].

02-12-2010

BMC cancer

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases.

02-12-2010

Prostate cancer and prostatic diseases

From bad to worse: comorbidity severity and quality of life after treatment for early-stage prostate cancer.

Journal of immunology (Baltimore, Md. : 1950)

The Pim kinase pathway contributes to survival signaling in primed CD8+ T cells upon CD27 costimulation.

International journal of radiation oncology, biology, physics

Clinical results of image-guided deep inspiration breath hold breast irradiation.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Potential value of color-coded dynamic breast-specific gamma-imaging; comparing (99m)Tc-(V)-DMSA, (99m)Tc-MIBI, and (99m)Tc-HDP in a mouse mammary tumor model.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Long-term compliance with endoscopic surveillance for familial adenomatous polyposis.

Familial cancer

Regular surveillance for Li-Fraumeni Syndrome: advice, adherence and perceived benefits.

Clinical and experimental immunology

Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma.

Breast cancer research and treatment

A practical approach to manage additional lesions at preoperative breast MRI in patients eligible for breast conserving therapy: results.

Nature genetics

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).

Journal of cell science

Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Review on the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and its phase I and phase II metabolites in biological matrices, foodstuff and beverages.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Ligands of epidermal growth factor receptor and the insulin-like growth factor family as serum biomarkers for response to epidermal growth factor receptor inhibitors in patients with advanced non-small cell lung cancer.