Publications

Trends in genetics : TIG

Knockout mouse models to study Wnt signal transduction.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

A validation study of the Dutch version of the Quality of Life-Cancer Survivor (QOL-CS) questionnaire in a group of prostate cancer survivors.

Developmental cell

Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells.

European journal of cancer (Oxford, England : 1990)

Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.

Cell

Re-evaluating cell-cycle regulation by E2Fs.

Journal of mass spectrometry : JMS

Quantitative analysis of gemcitabine triphosphate in human peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.

Cell cycle (Georgetown, Tex.)

Senescence, wound healing and cancer: the PAI-1 connection.

Genome research

Human heterochromatin proteins form large domains containing KRAB-ZNF genes.

British journal of cancer

Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapy.

20-11-2006

Cancer research

A causal role for the human tumor antigen preferentially expressed antigen of melanoma in cancer.

15-11-2006

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

New physiological functions for drug-transporting P-glycoproteins?

10-11-2006

Cancer

Long-term quality of life among Dutch prostate cancer survivors: results of a population-based study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Relationship between clinical factors and the incidence of toxicity after intra-arterial chemoradiation for head and neck cancer.

Nature genetics

Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C).

Clinical cancer research : an official journal of the American Association for Cancer Research

Flat dosing of carboplatin is justified in adult patients with normal renal function.

European journal of cancer (Oxford, England : 1990)

Better quality of life among 10-15 year survivors of Hodgkin's lymphoma compared to 5-9 year survivors: a population-based study.

European journal of cancer (Oxford, England : 1990)

Elderly patients with rectal cancer have a higher risk of treatment-related complications and a poorer prognosis than younger patients: a population-based study.

Cancer cell

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

European journal of cancer (Oxford, England : 1990)

Translation and validation of the SF-36 Health Survey for use among Turkish and Moroccan ethnic minority cancer patients in The Netherlands.

Nature reviews. Cancer

Polycomb silencers control cell fate, development and cancer.

Breast cancer research : BCR

Predicting a local recurrence after breast-conserving therapy by gene expression profiling.

31-10-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics.

15-10-2006

British journal of cancer

Phase II and pharmacological study of oral paclitaxel (Paxoral) plus ciclosporin in anthracycline-pretreated metastatic breast cancer.

09-10-2006

The Journal of cell biology

Kidney failure in mice lacking the tetraspanin CD151.

09-10-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical and pharmacologic study of the farnesyltransferase inhibitor tipifarnib in cancer patients with normal or mildly or moderately impaired hepatic function.

Journal of pharmacokinetics and pharmacodynamics

A semi-physiological population pharmacokinetic model describing the non-linear disposition of indisulam.

Clinical cancer research : an official journal of the American Association for Cancer Research

Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel.

Die Pharmazie

Pharmaceutical development, quality control, stability and compatibility of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum antineoplastic agent AP5346.

Medical physics

Clinical experience with EPID dosimetry for prostate IMRT pre-treatment dose verification.

Oncogene

Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.

25-09-2006

Nederlands tijdschrift voor geneeskunde

[Defining trials of medicinal products according to the revised Dutch Medical Research in Human Subjects Act (WMO)].

23-09-2006

Current biology : CB

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

19-09-2006

British journal of cancer

A novel self-microemulsifying formulation of paclitaxel for oral administration to patients with advanced cancer.

18-09-2006

Nature genetics

Characterization of the Drosophila melanogaster genome at the nuclear lamina.

Nature methods

shRNA libraries and their use in cancer genetics.

Journal of cellular physiology

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

Journal of mass spectrometry : JMS

Sensitive inductively coupled plasma mass spectrometry assay for the determination of platinum originating from cisplatin, carboplatin, and oxaliplatin in human plasma ultrafiltrate.

Methods in enzymology

DamID: mapping of in vivo protein-genome interactions using tethered DNA adenine methyltransferase.

30-08-2006

International journal of cancer

Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT).

15-08-2006

Proceedings of the National Academy of Sciences of the United States of America

Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster.

08-08-2006

The Journal of biological chemistry

A functional genetic screen identifies TFE3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growth factor-beta.

04-08-2006

Blood

Targeting self-antigens through allogeneic TCR gene transfer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy.

Cancer treatment reviews

Future opportunities in preventing cisplatin induced ototoxicity.

Basic & clinical pharmacology & toxicology

Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Phase I and pharmacokinetic study of combined treatment with perifosine and radiation in patients with advanced solid tumours.

Nature cell biology

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.

Genes & development

TXR1-mediated thrombospondin repression: a novel mechanism of resistance to taxanes?

European journal of clinical pharmacology

Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers.