Publications

Clinical cancer research : an official journal of the American Association for Cancer Research

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A.

01-10-1998

Journal of chromatography. B, Biomedical sciences and applications

High-performance liquid chromatographic determination of stabilized 4-hydroxyifosfamide in human plasma and erythrocytes.

25-09-1998

Journal of chromatography. B, Biomedical sciences and applications

Simultaneous determination of N,N',N"-triethylenethiophosphoramide, cyclophosphamide and some of their metabolites in plasma using capillary gas chromatography.

25-09-1998

The Journal of experimental medicine

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage.

07-09-1998

Anti-cancer drugs

Phase I and pharmacologic study of weekly doxorubicin and 1 h infusional paclitaxel in patients with advanced breast cancer.

01-09-1998

Pharmacological research

Pharmacologic study of 3-hour 135 mg M-2 paclitaxel in platinum pretreated patients with advanced ovarian cancer.

01-09-1998

Journal of pharmaceutical and biomedical analysis

High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma.

01-09-1998

Journal of chromatography. B, Biomedical sciences and applications

Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.

07-08-1998

Journal of the National Cancer Institute

Availability of PSC833, a substrate and inhibitor of P-glycoproteins, in various concentrations of serum.

05-08-1998

Anti-cancer drugs

O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan.

01-08-1998

Hepatology (Baltimore, Md.)

Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice.

01-08-1998

Journal of cell science

Removal and degradation of the free MHC class II beta chain in the endoplasmic reticulum requires proteasomes and is accelerated by BFA.

01-08-1998

Biochemical and biophysical research communications

Genomic organization of the human alpha 3 integrin subunit gene.

30-07-1998

The Journal of cell biology

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.

13-07-1998

Experimental lung research

Genetics of quantitative and qualitative aspects of lung tumorigenesis in the mouse: multiple interacting Susceptibility to lung cancer (Sluc) genes with large effects.

11-07-1998

Oncogene

Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse.

09-07-1998

Molecular and biochemical parasitology

The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.

01-07-1998

European journal of immunology

The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2.

01-07-1998

European journal of cancer (Oxford, England : 1990)

Quality of life assessment in daily clinical oncology practice: a feasibility study.

01-07-1998

Journal of clinical epidemiology

Comparison of patient and proxy EORTC QLQ-C30 ratings in assessing the quality of life of cancer patients.

01-07-1998

Blood

The bactericidal/permeability-increasing protein (BPI) is present in specific granules of human eosinophils.

15-06-1998

Journal of chromatography. B, Biomedical sciences and applications

Analysis of Ecteinascidin 743, a new potent marine-derived anticancer drug, in human plasma by high-performance liquid chromatography in combination with solid-phase extraction.

12-06-1998

Genes & development

p107 is a suppressor of retinoblastoma development in pRb-deficient mice.

01-06-1998

Electrophoresis

High performance density gradient electrophoresis of subcellular organelles, protein complexes and proteins.

01-06-1998

Journal of cell science

Ligand-independent role of the beta 4 integrin subunit in the formation of hemidesmosomes.

01-06-1998

Anti-cancer drugs

Continuous infusion of low-dose topotecan: pharmacokinetics and pharmacodynamics during a phase II study in patients with small cell lung cancer.

01-06-1998

Pharmacological research

The pharmacological role of P-glycoprotein in the intestinal epithelium.

01-06-1998

Cancer research

Comparative pharmacology of the novel cyclopropylpyrroloindole-prodrug carzelesin in mice, rats, and humans.

01-06-1998

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis.

01-06-1998

Molecular and cellular biology

Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes.

01-06-1998

Molecular and biochemical parasitology

Changes in expression site control and DNA modification in Trypanosoma brucei during differentiation of the bloodstream form to the procyclic form.

15-05-1998

Journal of chromatography. B, Biomedical sciences and applications

Influence of Cremophor EL on the quantification of paclitaxel in plasma using high-performance liquid chromatography with solid-phase extraction as sample pretreatment.

08-05-1998

Analytical biochemistry

The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling.

01-05-1998

Genes & development

Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.

15-04-1998

Cancer chemotherapy and pharmacology

A clinical pharmacokinetics study of carzelesin given by short-term intravenous infusion in a phase I study.

02-04-1998

Annals of oncology : official journal of the European Society for Medical Oncology

Malignant effusions contain lysophosphatidic acid (LPA)-like activity.

01-04-1998

The EMBO journal

The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.

01-04-1998

The Journal of clinical investigation

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

01-04-1998

The Journal of biological chemistry

CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.

27-03-1998

Current biology : CB

Exogenous phospholipase D generates lysophosphatidic acid and activates Ras, Rho and Ca2+ signaling pathways.

26-03-1998

The Journal of cell biology

Acute loss of cell-cell communication caused by G protein-coupled receptors: a critical role for c-Src.

09-03-1998

Proceedings of the National Academy of Sciences of the United States of America

beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.

03-03-1998

Cell adhesion and communication

Glomerular extracellular matrix components and integrins.

01-03-1998

Molecular and biochemical parasitology

Control of VSG gene expression sites in Trypanosoma brucei.

01-03-1998

Cancer treatment reviews

Cisplatin resistance and DNA repair.

18-02-1998

Journal of the National Cancer Institute

Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: high-dose versus standard-dose chemotherapy.

04-02-1998

Nederlands tijdschrift voor geneeskunde

[Last word on hormone replacement and breast cancer?].

17-01-1998

European journal of cancer (Oxford, England : 1990)

Intraperitoneal cisplatin with regional hyperthermia in advanced ovarian cancer: pharmacokinetics and cisplatin-DNA adduct formation in patients and ovarian cancer cell lines.

01-01-1998

Pharmacological research

Clinical research on antiangiogenic therapy.

01-01-1998

Methods in molecular medicine

Saturating mutagenesis and characterization of a herpesvirus genome using in vivo reconstitution of virus from cloned subgenomic regions.

01-01-1998

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A.

High-performance liquid chromatographic determination of stabilized 4-hydroxyifosfamide in human plasma and erythrocytes.

Simultaneous determination of N,N',N"-triethylenethiophosphoramide, cyclophosphamide and some of their metabolites in plasma using capillary gas chromatography.

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage.

Phase I and pharmacologic study of weekly doxorubicin and 1 h infusional paclitaxel in patients with advanced breast cancer.

Pharmacologic study of 3-hour 135 mg M-2 paclitaxel in platinum pretreated patients with advanced ovarian cancer.

High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma.

Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.

Availability of PSC833, a substrate and inhibitor of P-glycoproteins, in various concentrations of serum.

O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan.

Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice.

Removal and degradation of the free MHC class II beta chain in the endoplasmic reticulum requires proteasomes and is accelerated by BFA.

Genomic organization of the human alpha 3 integrin subunit gene.

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.

Genetics of quantitative and qualitative aspects of lung tumorigenesis in the mouse: multiple interacting Susceptibility to lung cancer (Sluc) genes with large effects.

Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse.

The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.

The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2.

Quality of life assessment in daily clinical oncology practice: a feasibility study.

Comparison of patient and proxy EORTC QLQ-C30 ratings in assessing the quality of life of cancer patients.

The bactericidal/permeability-increasing protein (BPI) is present in specific granules of human eosinophils.

Analysis of Ecteinascidin 743, a new potent marine-derived anticancer drug, in human plasma by high-performance liquid chromatography in combination with solid-phase extraction.

p107 is a suppressor of retinoblastoma development in pRb-deficient mice.

High performance density gradient electrophoresis of subcellular organelles, protein complexes and proteins.

Ligand-independent role of the beta 4 integrin subunit in the formation of hemidesmosomes.

Continuous infusion of low-dose topotecan: pharmacokinetics and pharmacodynamics during a phase II study in patients with small cell lung cancer.

The pharmacological role of P-glycoprotein in the intestinal epithelium.

Comparative pharmacology of the novel cyclopropylpyrroloindole-prodrug carzelesin in mice, rats, and humans.

The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis.

Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes.

Changes in expression site control and DNA modification in Trypanosoma brucei during differentiation of the bloodstream form to the procyclic form.

Influence of Cremophor EL on the quantification of paclitaxel in plasma using high-performance liquid chromatography with solid-phase extraction as sample pretreatment.

The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling.

Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.

A clinical pharmacokinetics study of carzelesin given by short-term intravenous infusion in a phase I study.

Malignant effusions contain lysophosphatidic acid (LPA)-like activity.

The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.

Exogenous phospholipase D generates lysophosphatidic acid and activates Ras, Rho and Ca2+ signaling pathways.

Acute loss of cell-cell communication caused by G protein-coupled receptors: a critical role for c-Src.

beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.

Glomerular extracellular matrix components and integrins.

Control of VSG gene expression sites in Trypanosoma brucei.

Cisplatin resistance and DNA repair.

Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: high-dose versus standard-dose chemotherapy.

[Last word on hormone replacement and breast cancer?].

Intraperitoneal cisplatin with regional hyperthermia in advanced ovarian cancer: pharmacokinetics and cisplatin-DNA adduct formation in patients and ovarian cancer cell lines.

Clinical research on antiangiogenic therapy.

Saturating mutagenesis and characterization of a herpesvirus genome using in vivo reconstitution of virus from cloned subgenomic regions.

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