Publications

Cancer chemotherapy and pharmacology

Disposition and metabolism of 14C-dovitinib (TKI258), an inhibitor of FGFR and VEGFR, after oral administration in patients with advanced solid tumors.

Magnetic resonance imaging

Functional MRI for radiotherapy dose painting.

Journal of biomedical optics

Optical coherence tomography in vulvar intraepithelial neoplasia.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Mediastinal lymph node position variability in non-small cell lung cancer patients treated with radical irradiation.

Medical physics

Validation of deformable registration in head and neck cancer using analysis of variance.

Bioanalysis

Quantitative determination of erlotinib and O-desmethyl erlotinib in human EDTA plasma and lung tumor tissue.

Head & neck

Preoperative imaging and surgical margins in maxillectomy patients.

European journal of radiology

Reducing the throughput time of the diagnostic track involving CT scanning with computer simulation.

The Journal of pathology

Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland.

Methods (San Diego, Calif.)

Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: from fixation to computation.

Cell

A missing link in genotype-directed cancer therapy.

26-10-2012

British journal of cancer

Risk and prognostic significance of metachronous contralateral testicular germ cell tumours.

23-10-2012

Physics in medicine and biology

Influence of the number of elongated fiducial markers on the localization accuracy of the prostate.

07-10-2012

The EMBO journal

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.

03-10-2012

PloS one

EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumors.

03-10-2012

European journal of haematology

Health-related quality of life and disease-specific complaints among multiple myeloma patients up to 10 yr after diagnosis: results from a population-based study using the PROFILES registry.

Annals of hematology

Perceived information provision and satisfaction among lymphoma and multiple myeloma survivors--results from a Dutch population-based study.

Patient education and counseling

Breast cancer genetic counseling after diagnosis but before treatment: a pilot study on treatment consequences and psychological impact.

International journal of radiation oncology, biology, physics

Acute esophagus toxicity in lung cancer patients after intensity modulated radiation therapy and concurrent chemotherapy.

The Journal of urology

Carboplatin based induction chemotherapy for nonorgan confined bladder cancer--a reasonable alternative for cisplatin unfit patients?

International journal of radiation oncology, biology, physics

Evaluation of tumor shape variability in head-and-neck cancer patients over the course of radiation therapy using implanted gold markers.

Psycho-oncology

Information about chemotherapy-associated cognitive problems contributes to cognitive problems in cancer patients.

Gynecologic oncology

Health related quality of life and symptoms after pelvic lymphadenectomy or radiotherapy vs. no adjuvant regional treatment in early-stage endometrial carcinoma: a large population-based study.

Annals of oncology : official journal of the European Society for Medical Oncology

Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004).

Clinical cancer research : an official journal of the American Association for Cancer Research

Alternative cleavage and polyadenylation during colorectal cancer development.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Understanding resistance to targeted cancer drugs through loss of function genetic screens.

Nature methods

Robust 4C-seq data analysis to screen for regulatory DNA interactions.

Bioinformatics (Oxford, England)

A regression model for estimating DNA copy number applied to capture sequencing data.

15-09-2012

Cell

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.

14-09-2012

The EMBO journal

An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.

12-09-2012

Cancer cell

Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis.

11-09-2012

Current biology : CB

Distinct roles of talin and kindlin in regulating integrin α5β1 function and trafficking.

11-09-2012

BMJ (Clinical research ed.)

Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK).

06-09-2012

Molecular pharmaceutics

Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.

04-09-2012

Patient education and counseling

Endometrial cancer survivors are unsatisfied with received information about diagnosis, treatment and follow-up: a study from the population-based PROFILES registry.

Annals of oncology : official journal of the European Society for Medical Oncology

Clinical correlates of 'BRCAness' in triple-negative breast cancer of patients receiving adjuvant chemotherapy.

Journal of gastroenterology

Excess weight among colorectal cancer survivors: target for intervention.

The American journal of pathology

Targeting BRAFV600E in an inducible murine model of melanoma.

Journal of cell science

The emerging role of Polycomb repressors in the response to DNA damage.

Nature reviews. Clinical oncology

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

Nature reviews. Cancer

The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance.

Journal of cellular and molecular medicine

Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling.

Cancer causes & control : CCC

Most colorectal cancer survivors live a large proportion of their remaining life in good health.

The AAPS journal

Performance of methods for handling missing categorical covariate data in population pharmacokinetic analyses.

Familial cancer

Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance.

European journal of cancer (Oxford, England : 1990)

Socio-economic implications of cancer survivorship: results from the PROFILES registry.