Publications

Molecular pharmaceutics

Oral availability and brain penetration of the B-RAFV600E inhibitor vemurafenib can be enhanced by the P-GLYCOprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

05-11-2012

Clinical lung cancer

Diffuse reflectance spectroscopy: a new guidance tool for improvement of biopsy procedures in lung malignancies.

01-11-2012

Journal of the European Academy of Dermatology and Venereology : JEADV

Melanoma patients receive more follow-up care than current guideline recommendations: a study of 546 patients from the general Dutch population.

01-11-2012

Clinical pharmacology and therapeutics

Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification.

01-11-2012

DNA repair

Effects of compound heterozygosity at the Xpd locus on cancer and ageing in mouse models.

01-11-2012

Methods (San Diego, Calif.)

Chromosome conformation capture on chip in single Drosophila melanogaster tissues.

01-11-2012

European journal of cancer (Oxford, England : 1990)

Higher prevalence of sexual dysfunction in colon and rectal cancer survivors compared with the normative population: a population-based study.

01-11-2012

Breast cancer research and treatment

Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.

01-11-2012

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Comparing higher order models for the EORTC QLQ-C30.

01-11-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D surface imaging for monitoring intrafraction motion in frameless stereotactic body radiotherapy of lung cancer.

01-11-2012

Cancer chemotherapy and pharmacology

Disposition and metabolism of 14C-dovitinib (TKI258), an inhibitor of FGFR and VEGFR, after oral administration in patients with advanced solid tumors.

01-11-2012

Magnetic resonance imaging

Functional MRI for radiotherapy dose painting.

01-11-2012

Journal of biomedical optics

Optical coherence tomography in vulvar intraepithelial neoplasia.

01-11-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Mediastinal lymph node position variability in non-small cell lung cancer patients treated with radical irradiation.

01-11-2012

Medical physics

Validation of deformable registration in head and neck cancer using analysis of variance.

01-11-2012

Bioanalysis

Quantitative determination of erlotinib and O-desmethyl erlotinib in human EDTA plasma and lung tumor tissue.

01-11-2012

Head & neck

Preoperative imaging and surgical margins in maxillectomy patients.

01-11-2012

European journal of radiology

Reducing the throughput time of the diagnostic track involving CT scanning with computer simulation.

01-11-2012

The Journal of pathology

Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland.

01-11-2012

Methods (San Diego, Calif.)

Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: from fixation to computation.

01-11-2012

Cell

A missing link in genotype-directed cancer therapy.

26-10-2012

British journal of cancer

Risk and prognostic significance of metachronous contralateral testicular germ cell tumours.

23-10-2012

Physics in medicine and biology

Influence of the number of elongated fiducial markers on the localization accuracy of the prostate.

07-10-2012

The EMBO journal

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.

03-10-2012

PloS one

EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumors.

03-10-2012

European journal of haematology

Health-related quality of life and disease-specific complaints among multiple myeloma patients up to 10 yr after diagnosis: results from a population-based study using the PROFILES registry.

01-10-2012

Annals of hematology

Perceived information provision and satisfaction among lymphoma and multiple myeloma survivors--results from a Dutch population-based study.

01-10-2012

Patient education and counseling

Breast cancer genetic counseling after diagnosis but before treatment: a pilot study on treatment consequences and psychological impact.

01-10-2012

International journal of radiation oncology, biology, physics

Acute esophagus toxicity in lung cancer patients after intensity modulated radiation therapy and concurrent chemotherapy.

01-10-2012

The Journal of urology

Carboplatin based induction chemotherapy for nonorgan confined bladder cancer--a reasonable alternative for cisplatin unfit patients?

01-10-2012

International journal of radiation oncology, biology, physics

Evaluation of tumor shape variability in head-and-neck cancer patients over the course of radiation therapy using implanted gold markers.

01-10-2012

Psycho-oncology

Information about chemotherapy-associated cognitive problems contributes to cognitive problems in cancer patients.

01-10-2012

Gynecologic oncology

Health related quality of life and symptoms after pelvic lymphadenectomy or radiotherapy vs. no adjuvant regional treatment in early-stage endometrial carcinoma: a large population-based study.

01-10-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004).

01-10-2012

Clinical cancer research : an official journal of the American Association for Cancer Research

Alternative cleavage and polyadenylation during colorectal cancer development.

01-10-2012

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Understanding resistance to targeted cancer drugs through loss of function genetic screens.

01-10-2012

Nature methods

Robust 4C-seq data analysis to screen for regulatory DNA interactions.

01-10-2012

Bioinformatics (Oxford, England)

A regression model for estimating DNA copy number applied to capture sequencing data.

15-09-2012

Cell

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.

14-09-2012

The EMBO journal

An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.

12-09-2012

Cancer cell

Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis.

11-09-2012

Current biology : CB

Distinct roles of talin and kindlin in regulating integrin α5β1 function and trafficking.

11-09-2012

BMJ (Clinical research ed.)

Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK).

06-09-2012

Molecular pharmaceutics

Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.

04-09-2012

Patient education and counseling

Endometrial cancer survivors are unsatisfied with received information about diagnosis, treatment and follow-up: a study from the population-based PROFILES registry.

01-09-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Clinical correlates of 'BRCAness' in triple-negative breast cancer of patients receiving adjuvant chemotherapy.

01-09-2012

Journal of gastroenterology

Excess weight among colorectal cancer survivors: target for intervention.

01-09-2012

The American journal of pathology

Targeting BRAFV600E in an inducible murine model of melanoma.

01-09-2012

Journal of cell science

The emerging role of Polycomb repressors in the response to DNA damage.

01-09-2012

Nature reviews. Clinical oncology

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

01-09-2012