Publications

Cancer chemotherapy and pharmacology

Phase I study of lonafarnib (SCH66336) in combination with trastuzumab plus paclitaxel in Her2/neu overexpressing breast cancer: EORTC study 16023.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Optical sensing for tumor detection in the liver.

Breast cancer research and treatment

Diffuse reflectance spectroscopy: towards clinical application in breast cancer.

Therapeutic advances in medical oncology

Standard-dose tegafur-uracil (UFT) is not a safe alternative in partial dihydropyrimidine dehydrogenase-deficient patients.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Development of an oral solid dispersion formulation for use in low-dose metronomic chemotherapy of paclitaxel.

Practical radiation oncology

Required target margins for image-guided lung SBRT: Assessment of target position intrafraction and correction residuals.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Prognostication and prediction using gene expression profiling in oesophageal cancer.

Cellular and molecular life sciences : CMLS

MAPK uncouples cell cycle progression from cell spreading and cytoskeletal organization in cycling cells.

Breast cancer research and treatment

SERPINA6, BEX1, AGTR1, SLC26A3, and LAPTM4B are markers of resistance to neoadjuvant chemotherapy in HER2-negative breast cancer.

Cancer discovery

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Relating acute esophagitis to radiotherapy dose using FDG-PET in concurrent chemo-radiotherapy for locally advanced non-small cell lung cancer.

Advances in biological regulation

Structure-function relationships of autotaxin, a secreted lysophospholipase D.

Cancer research

A preclinical mouse model of invasive lobular breast cancer metastasis.

BMC medical genomics

Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.

31-12-2012

The Journal of biological chemistry

Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration.

28-12-2012

Genes Dev.: Genes & development

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny

27-12-2012

Proceedings of the National Academy of Sciences of the United States of America

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.

26-12-2012

The oncologist

Critical appraisal of translational research models for suitability in performance assessment of cancer centers.

25-12-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Risk of treatment-related esophageal cancer among breast cancer survivors.

Pharmaceutical research

Model-based evaluation and optimization of cardiac monitoring protocols for adjuvant treatment of breast cancer with trastuzumab.

Breast (Edinburgh, Scotland)

Additional value of the 70-gene signature and levels of ER and PR for the prediction of outcome in tamoxifen-treated ER-positive breast cancer.

Human gene therapy

Rational design of DNA vaccines for the induction of human papillomavirus type 16 E6- and E7-specific cytotoxic T-cell responses.

Trends in biochemical sciences

Switching Polo-like kinase-1 on and off in time and space.

Cancer chemotherapy and pharmacology

Pharmacokinetics of eribulin mesylate in patients with solid tumors and hepatic impairment.

Human brain mapping

Late effects of high-dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: converging results from multimodal magnetic resonance imaging.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Lack of tumor uptake of 131-I labeled rituximab in a patient with a CD20 positive lymphoma lesion.

European journal of nuclear medicine and molecular imaging

Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Radioguided occult lesion localisation (ROLL) in breast-conserving surgery after neoadjuvant chemotherapy.

Proceedings of the National Academy of Sciences of the United States of America

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

27-11-2012

Cell

MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.

21-11-2012

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Efficacy of cognitive behavioral therapy and physical exercise in alleviating treatment-induced menopausal symptoms in patients with breast cancer: results of a randomized, controlled, multicenter trial.

20-11-2012

BMJ (Clinical research ed.)

Commentary: Substandard medicines are the priority for neglected tropical diseases.

14-11-2012

The Journal of biological chemistry

Intrinsic flexibility of ubiquitin on proliferating cell nuclear antigen (PCNA) in translesion synthesis.

09-11-2012

American journal of nuclear medicine and molecular imaging

Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist.

08-11-2012

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

Can adjuvant chemoradiotherapy replace extended lymph node dissection in gastric cancer?

07-11-2012

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

Treatment dilemmas in patients with synchronous colorectal liver metastases.

07-11-2012

Molecular pharmaceutics

Oral availability and brain penetration of the B-RAFV600E inhibitor vemurafenib can be enhanced by the P-GLYCOprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

05-11-2012

Clinical lung cancer

Diffuse reflectance spectroscopy: a new guidance tool for improvement of biopsy procedures in lung malignancies.

Journal of the European Academy of Dermatology and Venereology : JEADV

Melanoma patients receive more follow-up care than current guideline recommendations: a study of 546 patients from the general Dutch population.

Clinical pharmacology and therapeutics

Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification.

DNA repair

Effects of compound heterozygosity at the Xpd locus on cancer and ageing in mouse models.

Methods (San Diego, Calif.)

Chromosome conformation capture on chip in single Drosophila melanogaster tissues.

European journal of cancer (Oxford, England : 1990)

Higher prevalence of sexual dysfunction in colon and rectal cancer survivors compared with the normative population: a population-based study.

Breast cancer research and treatment

Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Comparing higher order models for the EORTC QLQ-C30.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D surface imaging for monitoring intrafraction motion in frameless stereotactic body radiotherapy of lung cancer.

Cancer chemotherapy and pharmacology

Disposition and metabolism of 14C-dovitinib (TKI258), an inhibitor of FGFR and VEGFR, after oral administration in patients with advanced solid tumors.

Magnetic resonance imaging

Functional MRI for radiotherapy dose painting.

Journal of biomedical optics

Optical coherence tomography in vulvar intraepithelial neoplasia.