Publications

Physics in medicine and biology

Image navigation as a means to expand the boundaries of fluorescence-guided surgery.

21-05-2012

Journal of palliative care

Severe cannabinoid intoxication in a patient with non-small-cell lung cancer.

16-05-2012

Genes & development

Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.

15-05-2012

PloS one

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.

11-05-2012

PloS one

Self-reported physical activity: its correlates and relationship with health-related quality of life in a large cohort of colorectal cancer survivors.

09-05-2012

British journal of cancer

A phase I study of E7080, a multitargeted tyrosine kinase inhibitor, in patients with advanced solid tumours.

08-05-2012

Cancer research

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors.

01-05-2012

The Journal of clinical investigation

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

01-05-2012

Psycho-oncology

Self-reported cognitive functioning in postmenopausal breast cancer patients before and during endocrine treatment: findings from the neuropsychological TEAM side-study.

01-05-2012

Cancer

Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study.

01-05-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature.

01-05-2012

Cell

The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites.

27-04-2012

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of LC-MS/MS assays for the quantification of bendamustine and its metabolites in human plasma and urine.

15-04-2012

Cell cycle (Georgetown, Tex.)

Posttranslational control of telomere maintenance and the telomere damage response.

15-04-2012

The oncologist

Lapatinib for advanced or metastatic breast cancer.

06-04-2012

The Journal of pharmacology and experimental therapeutics

P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) restrict brain accumulation of the active sunitinib metabolite N-desethyl sunitinib.

01-04-2012

Molecular biology of the cell

Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly.

01-04-2012

Acta crystallographica. Section D, Biological crystallography

PDB_REDO: constructive validation, more than just looking for errors.

01-04-2012

Investigational new drugs

Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP.

01-04-2012

Breast cancer research and treatment

Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH.

01-04-2012

Acta oncologica (Stockholm, Sweden)

Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients - results of the Dutch Scalp Cooling Registry.

01-04-2012

General hospital psychiatry

Type D personality is associated with increased comorbidity burden and health care utilization among 3080 cancer survivors.

31-03-2012

Advances in immunology

Behavior and function of tissue-resident memory T cells.

28-03-2012

International journal of radiation oncology, biology, physics

Image-guided radiotherapy for left-sided breast cancer patients: geometrical uncertainty of the heart.

15-03-2012

BMC medical informatics and decision making

A review on the relation between simulation and improvement in hospitals.

14-03-2012

Nat Med: Nature medicine

Chemotherapy response of spontaneous mammary tumors is independent of the adaptive immune system

06-03-2012

Drug Resist Updates: reviews and commentaries in antimicrobial and anticancer chemotherapy

A rapidly growing number of therapeutics targeting tumor cell-intrinsic and -extrinsic processes is under development for individualized treatment of cancer patients

01-03-2012

Current opinion in urology

Fluorescence guidance in urologic surgery.

01-03-2012

Journal of clinical pharmacology

From mouse to man: predictions of human pharmacokinetics of orally administered docetaxel from preclinical studies.

01-03-2012

Nucleus (Austin, Tex.)

Hox in space: gene cluster regulation linked to folding of chromatin.

01-03-2012

International journal of radiation oncology, biology, physics

Quantification of the variability of diaphragm motion and implications for treatment margin construction.

01-03-2012

Nucleus (Austin, Tex.)

Fusing telomeres with RNF8.

01-03-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Repeat CT assessed CTV variation and PTV margins for short- and long-course pre-operative RT of rectal cancer.

01-03-2012

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of LC-MS/MS assays for the quantification of E7080 and metabolites in various human biological matrices.

01-03-2012

European journal of immunology

Reduced tumor-antigen density leads to PD-1/PD-L1-mediated impairment of partially exhausted CD8⁺ T cells.

01-03-2012

Future oncology (London, England)

Optical spectroscopy: current advances and future applications in cancer diagnostics and therapy.

01-03-2012

Mol Cell Proteomics: Molecular & cellular proteomics: MCP

Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer

24-02-2012

Nature

Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours.

22-02-2012

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Drug resistance in the mouse cancer clinic.

18-02-2012

Breast cancer research and treatment

Neoadjuvant chemotherapy in ER+ HER2- breast cancer: response prediction based on immunohistochemical and molecular characteristics.

01-02-2012

Trends in pharmacological sciences

Functions of OATP1A and 1B transporters in vivo: insights from mouse models.

01-02-2012

Epigenomics

Crosstalk between aging and the epigenome.

01-02-2012

The Journal of clinical investigation

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

01-02-2012

Journal of clinical pharmacology

Model-based evaluation of similarity in pharmacokinetics of two formulations of the blood-derived plasma product c1 esterase inhibitor.

01-02-2012

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Integration of a smoking cessation program in the treatment protocol for patients with head and neck and lung cancer.

01-02-2012

Breast cancer research and treatment

Deoxycytidine kinase is overexpressed in poor outcome breast cancer and determines responsiveness to nucleoside analogs.

01-02-2012

Lung cancer (Amsterdam, Netherlands)

Circulating tumor cell detection in advanced non-small cell lung cancer patients by multi-marker QPCR analysis.

01-02-2012

Current opinion in genetics & development

Using genetically engineered mouse models to validate candidate cancer genes and test new therapeutic approaches.

01-02-2012

Drug metabolism and disposition: the biological fate of chemicals

Mass balance study of [¹⁴C]eribulin in patients with advanced solid tumors.

01-02-2012

Nature

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

26-01-2012