Publications

Molecular pharmacology

Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure.

Lung cancer (Amsterdam, Netherlands)

Improved identification of peripheral lung tumors by using diffuse reflectance and fluorescence spectroscopy.

Journal of cell science

UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway.

European journal of cancer (Oxford, England : 1990)

Quantifying fatigue in (long-term) colorectal cancer survivors: a study from the population-based patient reported outcomes following initial treatment and long term evaluation of survivorship registry.

Communicative & integrative biology

Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation.

Science (New York, N.Y.)

Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry.

26-04-2013

Frontiers in oncology

Loss of telomere protection: consequences and opportunities.

19-04-2013

The Journal of cell biology

Systematic dissection of dynein regulators in mitosis.

15-04-2013

Clinical cancer research : an official journal of the American Association for Cancer Research

Abcc4 together with abcb1 and abcg2 form a robust cooperative drug efflux system that restricts the brain entry of camptothecin analogues.

15-04-2013

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantification of cabazitaxel, its metabolite docetaxel and the determination of the demethylated metabolites RPR112698 and RPR123142 as docetaxel equivalents in human plasma by liquid chromatography-tandem mass spectrometry.

15-04-2013

Nature

Diverse and heritable lineage imprinting of early haematopoietic progenitors.

11-04-2013

The Journal of experimental medicine

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.

08-04-2013

Investigational new drugs

Eribulin mesylate pharmacokinetics in patients with solid tumors receiving repeated oral ketoconazole.

Therapeutic drug monitoring

Quantification of sunitinib and N-desethyl sunitinib in human EDTA plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry: validation and application in routine therapeutic drug monitoring.

Nature reviews. Nephrology

Cell-matrix adhesion of podocytes in physiology and disease.

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

Current opinion in immunology

Human cancer regression antigens.

Endocrine-related cancer

Rising incidence, no change in survival and decreasing mortality from thyroid cancer in The Netherlands since 1989.

Current opinion in genetics & development

Chromatin organization: form to function.

Gynecologic oncology

The relationship of body mass index with quality of life among endometrial cancer survivors: a study from the population-based PROFILES registry.

Molecular oncology

Mouse models for lung cancer.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Response to induction chemotherapy and surgery in non-organ confined bladder cancer: a single institution experience.

Molecular oncology

Genetically engineered mouse models of PI3K signaling in breast cancer.

The Netherlands journal of medicine

Recent advances towards the clinical application of DNA vaccines.

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

Biomedical chromatography : BMC

Method development and validation for the quantification of dasatinib, erlotinib, gefitinib, imatinib, lapatinib, nilotinib, sorafenib and sunitinib in human plasma by liquid chromatography coupled with tandem mass spectrometry.

International journal of radiation oncology, biology, physics

Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study.

Cell

Single-cell dynamics of genome-nuclear lamina interactions.

28-03-2013

Proceedings of the National Academy of Sciences of the United States of America

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis.

26-03-2013

International journal of radiation oncology, biology, physics

Targeted radiosensitization by the Chk1 inhibitor SAR-020106.

15-03-2013

The Journal of biological chemistry

Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.

15-03-2013

Blood

Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function.

14-03-2013

Cancer nursing

The Cancer Worry Scale: detecting fear of recurrence in breast cancer survivors.

02-03-2013

Drugs in R&D

Pharmacokinetics and excretion of 14C-bendamustine in patients with relapsed or refractory malignancy.

The Journal of biological chemistry

Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.

Cancer immunology, immunotherapy : CII

Mimicking homeostatic proliferation in vitro generates T cells with high anti-tumor function in non-lymphopenic hosts.

The Journal of pathology

An α-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer.

Journal of radiation oncology

Volume changes in soft tissue sarcomas during preoperative radiotherapy of extremities evaluated using cone-beam CT.

Journal of palliative medicine

Information provision and patient reported outcomes in patients with metastasized colorectal cancer: results from the PROFILES registry.

Biochimica et biophysica acta

Anticancer mechanisms and clinical application of alkylphospholipids.

Annals of oncology : official journal of the European Society for Medical Oncology

Early development of the metabolic syndrome after chemotherapy for testicular cancer.

Analytical and bioanalytical chemistry

Pharmacodynamic assay of thymidylate synthase activity in peripheral blood mononuclear cells.

Haematologica

A high level of fatigue among long-term survivors of non-Hodgkin's lymphoma: results from the longitudinal population-based PROFILES registry in the south of the Netherlands.

Psycho-oncology

Illness perceptions in cancer survivors: what is the role of information provision?

Analytical and bioanalytical chemistry

Correction of peripheral blood mononuclear cell cytosolic protein for hemoglobin contamination.