Publications

Trends in pharmacological sciences

Functions of OATP1A and 1B transporters in vivo: insights from mouse models.

Epigenomics

Crosstalk between aging and the epigenome.

The Journal of clinical investigation

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

Journal of clinical pharmacology

Model-based evaluation of similarity in pharmacokinetics of two formulations of the blood-derived plasma product c1 esterase inhibitor.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Integration of a smoking cessation program in the treatment protocol for patients with head and neck and lung cancer.

Breast cancer research and treatment

Deoxycytidine kinase is overexpressed in poor outcome breast cancer and determines responsiveness to nucleoside analogs.

Lung cancer (Amsterdam, Netherlands)

Circulating tumor cell detection in advanced non-small cell lung cancer patients by multi-marker QPCR analysis.

Current opinion in genetics & development

Using genetically engineered mouse models to validate candidate cancer genes and test new therapeutic approaches.

Drug metabolism and disposition: the biological fate of chemicals

Mass balance study of [¹⁴C]eribulin in patients with advanced solid tumors.

Nature

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

26-01-2012

Journal of cell science

Dynamics within tetraspanin pairs affect MHC class II expression.

15-01-2012

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Ipilimumab-induced sarcoidosis in a patient with metastatic melanoma undergoing complete remission.

10-01-2012

Medical physics

In aqua vivo EPID dosimetry.

The Journal of pathology

Fancf-deficient mice are prone to develop ovarian tumours.

Results in immunology

Testing for HLA/peptide tetramer-binding to the T cell receptor complex on human T lymphocytes.

Pharmacoepidemiology and drug safety

Record linkage for pharmacoepidemiological studies in cancer patients.

Cell cycle (Georgetown, Tex.)

News about old histones: a role for histone age in controlling the epigenome.

Cellular and molecular life sciences : CMLS

Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers.

Biomaterials

Targeted non-covalent self-assembled nanoparticles based on human serum albumin.

Cancer chemotherapy and pharmacology

Gene polymorphisms, pharmacokinetics, and hematological toxicity in advanced non-small-cell lung cancer patients receiving cisplatin/gemcitabine.

Genes & development

A decade of 3C technologies: insights into nuclear organization.

The Journal of clinical investigation

Blood pressure influences end-stage renal disease of Cd151 knockout mice.

International journal of cancer

Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration.

Journal of clinical laboratory analysis

Search for breast cancer biomarkers in fractionated serum samples by protein profiling with SELDI-TOF MS.

Journal of affective disorders

Type D (distressed) personality is associated with poor quality of life and mental health among 3080 cancer survivors.

Breast cancer research and treatment

Head-to-head comparison of the 70-gene signature versus the 21-gene assay: cost-effectiveness and the effect of compliance.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Genetic variants in TGFβ-1 and PAI-1 as possible risk factors for cardiovascular disease after radiotherapy for breast cancer.

PloS one

LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor.

24-12-2011

Chemistry & biology

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

23-12-2011

The Journal of experimental medicine

A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.

19-12-2011

Bioinformatics (Oxford, England)

Automatic rebuilding and optimization of crystallographic structures in the Protein Data Bank.

15-12-2011

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

High-performance liquid chromatography analysis of a novel small-molecule, anti-cancer drug, Palomid 529, in human and mouse plasma and in mouse tissue homogenates.

15-12-2011

Cancer cell

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

13-12-2011

Molecular pharmaceutics

Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression.

05-12-2011

Trials

The impact of a cancer Survivorship Care Plan on gynecological cancer patient and health care provider reported outcomes (ROGY Care): study protocol for a pragmatic cluster randomized controlled trial.

05-12-2011

Lancet (London, England)

Tilting the AXIS towards therapeutic limits in renal cancer.

03-12-2011

Journal of clinical epidemiology

Validation study suggested no differential misclassification of self-reported mammography history in BRCA1/2 mutation carriers.

Bioanalysis

Bioanalytical aspects of clinical mass balance studies in oncology.

Genome research

High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors.

Cancer treatment reviews

Circulating tumor cells as pharmacodynamic biomarker in early clinical oncological trials.

Biochemical Society transactions

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton.

Pigment cell & melanoma research

Oncogene-induced senescence and melanoma: where do we stand?

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Suffering in long-term cancer survivors: an evaluation of the PRISM-R2 in a population-based cohort.

Melanoma research

Expression of the embryological morphogen Nodal in stage III/IV melanoma.

Human reproduction (Oxford, England)

Risk of borderline and invasive ovarian tumours after ovarian stimulation for in vitro fertilization in a large Dutch cohort.

Journal of cancer research and clinical oncology

Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer.