Publications

The British journal of surgery

Impact of concentration of oesophageal and gastric cardia cancer surgery on long-term population-based survival.

Genes & development

The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA.

Nucleic acids research

The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.

Clinical pharmacology and therapeutics

Population pharmacokinetic-pharmacodynamic analysis of trastuzumab-associated cardiotoxicity.

Breast cancer research and treatment

Improved survival of patients with primary distant metastatic breast cancer in the period of 1995-2008. A nationwide population-based study in the Netherlands.

Nature cell biology

Variegated gene expression caused by cell-specific long-range DNA interactions.

26-06-2011

Cancer cell

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

14-06-2011

The oncologist

Part 4: pharmacogenetic variability in anticancer pharmacodynamic drug effects.

11-06-2011

The oncologist

Part 3: Pharmacogenetic variability in phase II anticancer drug metabolism.

11-06-2011

British journal of cancer

A multimarker QPCR-based platform for the detection of circulating tumour cells in patients with early-stage breast cancer.

07-06-2011

The oncologist

Part 2: pharmacogenetic variability in drug transport and phase I anticancer drug metabolism.

03-06-2011

The oncologist

Part 1: background, methodology, and clinical adoption of pharmacogenetics.

03-06-2011

The oncologist

Trastuzumab.

03-06-2011

PLoS biology

Patterns and mechanisms of ancestral histone protein inheritance in budding yeast.

Genetics in medicine : official journal of the American College of Medical Genetics

Compliance with periodic surveillance for Von-Hippel-Lindau disease.

The AAPS journal

Evaluation of α2-integrin expression as a biomarker for tumor growth inhibition for the investigational integrin inhibitor E7820 in preclinical and clinical studies.

International journal of radiation oncology, biology, physics

Residual seminal vesicle displacement in marker-based image-guided radiotherapy for prostate cancer and the impact on margin design.

Climacteric : the journal of the International Menopause Society

Characteristics of breast cancer patients who experience menopausal transition due to treatment.

The Journal of pharmacology and experimental therapeutics

P-glycoprotein (ABCB1) transports the primary active tamoxifen metabolites endoxifen and 4-hydroxytamoxifen and restricts their brain penetration.

Pharmacological reviews

A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Quality of life and consequences for daily life of familial adenomatous polyposis (FAP) family members.

Psycho-oncology

Distress in partners of individuals diagnosed with or at high risk of developing tumors due to rare hereditary cancer syndromes.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of a quantitative assay for the determination of tamoxifen and its five main phase I metabolites in human serum using liquid chromatography coupled with tandem mass spectrometry.

Journal of pharmaceutical and biomedical analysis

Investigational study of tamoxifen phase I metabolites using chromatographic and spectroscopic analytical techniques.

Current oncology reports

Non-clear cell renal cell carcinoma: how new biological insight may lead to new therapeutic modalities.

Bioconjugate chemistry

Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide.

18-05-2011

The EMBO journal

Chromatin: constructing the big picture.

18-05-2011

Cancer

Overall survival and PD-L1 expression in metastasized malignant melanoma.

15-05-2011

Clinical cancer research : an official journal of the American Association for Cancer Research

Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer.

15-05-2011

Human antibodies

CD20 antigen imaging with ¹²⁴I-rituximab PET/CT in patients with rheumatoid arthritis.

12-05-2011

Human antibodies

The pharmacokinetics of ¹²⁴I-rituximab in patients with rheumatoid arthritis.

12-05-2011

Human antibodies

The pharmacokinetics of ¹³¹I-rituximab in a patient with CD20 positive non-Hodgkin Lymphoma: evaluation of the effect of radioiodination on the biological properties of rituximab.

12-05-2011

The EMBO journal

Antagonistic TSC22D1 variants control BRAF(E600)-induced senescence.

04-05-2011

Tumori

Serum beta-HCG and CA-125 as tumor markers in a patient with osteosarcoma: case report.

03-05-2011

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-term outcome and quality of life of patients with endometrial carcinoma treated with or without pelvic radiotherapy in the post operative radiation therapy in endometrial carcinoma 1 (PORTEC-1) trial.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Validation of high-performance liquid chromatography-tandem mass spectrometry assays for the quantification of eribulin (E7389) in various biological matrices.

International journal of radiation oncology, biology, physics

Three-dimensional analysis of recurrence patterns in rectal cancer: the cranial border in hypofractionated preoperative radiotherapy can be lowered.

The Journal of pathology

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.

Disease models & mechanisms

Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice.

The Journal of pathology

Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system.

Drug metabolism and disposition: the biological fate of chemicals

Differential impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on axitinib brain accumulation and oral plasma pharmacokinetics.

Breast cancer research and treatment

Sentinel node micrometastases in breast cancer do not affect prognosis: a population-based study.

Annals of oncology : official journal of the European Society for Medical Oncology

The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer.