Publications

Bioanalysis

Bioanalytical aspects of clinical mass balance studies in oncology.

Genome research

High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors.

Cancer treatment reviews

Circulating tumor cells as pharmacodynamic biomarker in early clinical oncological trials.

Biochemical Society transactions

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton.

Pigment cell & melanoma research

Oncogene-induced senescence and melanoma: where do we stand?

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Suffering in long-term cancer survivors: an evaluation of the PRISM-R2 in a population-based cohort.

Melanoma research

Expression of the embryological morphogen Nodal in stage III/IV melanoma.

Human reproduction (Oxford, England)

Risk of borderline and invasive ovarian tumours after ovarian stimulation for in vitro fertilization in a large Dutch cohort.

Journal of cancer research and clinical oncology

Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer.

International journal of pharmaceutics

Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001).

28-11-2011

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Compromised health-related quality of life in patients with low-grade glioma.

20-11-2011

Nederlands tijdschrift voor geneeskunde

[Measuring quality of life in every oncological patient].

17-11-2011

Nederlands tijdschrift voor geneeskunde

[Issues around melanoma].

17-11-2011

The Biochemical journal

Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells.

15-11-2011

International journal of radiation oncology, biology, physics

Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma.

15-11-2011

Hum Mutat: Human mutation

ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes

03-11-2011

BMC cancer

A cost-effectiveness analysis of a preventive exercise program for patients with advanced head and neck cancer treated with concomitant chemo-radiotherapy.

03-11-2011

International journal of radiation oncology, biology, physics

Impact of preoperative radiotherapy on general and disease-specific health status of rectal cancer survivors: a population-based study.

Breast cancer research and treatment

A non-BRCA1/2 hereditary breast cancer sub-group defined by aCGH profiling of genetically related patients.

Breast cancer research and treatment

Association of the germline TP53 R72P and MDM2 SNP309 variants with breast cancer survival in specific breast tumor subgroups.

Lung cancer (Amsterdam, Netherlands)

Tubulin, BRCA1, ERCC1, Abraxas, RAP80 mRNA expression, p53/p21 immunohistochemistry and clinical outcome in patients with advanced non small-cell lung cancer receiving first-line platinum-gemcitabine chemotherapy.

Annals of oncology : official journal of the European Society for Medical Oncology

Phase I evaluation of telatinib, a VEGF receptor tyrosine kinase inhibitor, in combination with bevacizumab in subjects with advanced solid tumors.

International journal of radiation oncology, biology, physics

Image-guided radiotherapy for breast cancer patients: surgical clips as surrogate for breast excision cavity.

Breast cancer research : BCR

Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness.

27-10-2011

Nature communications

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity.

25-10-2011

PloS one

3'UTR-mediated gene silencing of the Mixed Lineage Leukemia (MLL) gene.

15-10-2011

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry.

15-10-2011

The EMBO journal

Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer.

14-10-2011

DNA repair

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance.

10-10-2011

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Management of hot flashes in patients who have breast cancer with venlafaxine and clonidine: a randomized, double-blind, placebo-controlled trial.

10-10-2011

PloS one

The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.

08-10-2011

Molecular cell

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.

07-10-2011

PLoS genetics

A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover.

Current opinion in cell biology

Mechanisms of integrin activation and trafficking.

European urology

Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer.

Urology

A phase II study of presurgical sunitinib in patients with metastatic clear-cell renal carcinoma and the primary tumor in situ.

Investigational new drugs

Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice.

Journal of analytical toxicology

Determination of sunitinib and its active metabolite N-desethylsunitinib in sweat of a patient.

Cancer immunology, immunotherapy : CII

Combination of targeted therapy and immunotherapy in melanoma.

Clinical endocrinology

Health-related quality of life among thyroid cancer survivors: a systematic review.