Publications

Molecular systems biology

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling.

24-01-2013

The EMBO journal

The cancer antigenome.

23-01-2013

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Sensitive method for plasma and tumor Ko143 quantification using reversed-phase high-performance liquid chromatography and fluorescence detection.

15-01-2013

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantitative determination of capecitabine and its six metabolites in human plasma using liquid chromatography coupled to electrospray tandem mass spectrometry.

15-01-2013

PLoS One

Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS

11-01-2013

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

Directional interpolation for motion weighted 4D cone-beam CT reconstruction.

05-01-2013

The Journal of biological chemistry

The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.

04-01-2013

Chembiochem : a European journal of chemical biology

Development of a hypersensitive periodate-cleavable amino acid that is methionine- and disulfide-compatible and its application in MHC exchange reagents for T cell characterisation.

02-01-2013

Proceedings of the National Academy of Sciences of the United States of America

Spatiotemporal analysis of organelle and macromolecular complex inheritance.

02-01-2013

Maturitas

Effect of diabetes on endometrial cancer recurrence and survival.

01-01-2013

Cancer chemotherapy and pharmacology

Phase I study of lonafarnib (SCH66336) in combination with trastuzumab plus paclitaxel in Her2/neu overexpressing breast cancer: EORTC study 16023.

01-01-2013

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Optical sensing for tumor detection in the liver.

01-01-2013

Breast cancer research and treatment

Diffuse reflectance spectroscopy: towards clinical application in breast cancer.

01-01-2013

Therapeutic advances in medical oncology

Standard-dose tegafur-uracil (UFT) is not a safe alternative in partial dihydropyrimidine dehydrogenase-deficient patients.

01-01-2013

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Development of an oral solid dispersion formulation for use in low-dose metronomic chemotherapy of paclitaxel.

01-01-2013

Practical radiation oncology

Required target margins for image-guided lung SBRT: Assessment of target position intrafraction and correction residuals.

01-01-2013

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Prognostication and prediction using gene expression profiling in oesophageal cancer.

01-01-2013

Cellular and molecular life sciences : CMLS

MAPK uncouples cell cycle progression from cell spreading and cytoskeletal organization in cycling cells.

01-01-2013

Breast cancer research and treatment

SERPINA6, BEX1, AGTR1, SLC26A3, and LAPTM4B are markers of resistance to neoadjuvant chemotherapy in HER2-negative breast cancer.

01-01-2013

Cancer discovery

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

01-01-2013

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Relating acute esophagitis to radiotherapy dose using FDG-PET in concurrent chemo-radiotherapy for locally advanced non-small cell lung cancer.

01-01-2013

Advances in biological regulation

Structure-function relationships of autotaxin, a secreted lysophospholipase D.

01-01-2013

Cancer research

A preclinical mouse model of invasive lobular breast cancer metastasis.

01-01-2013

BMC medical genomics

Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.

31-12-2012

The Journal of biological chemistry

Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration.

28-12-2012

Genes Dev.: Genes & development

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny

27-12-2012

Proceedings of the National Academy of Sciences of the United States of America

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.

26-12-2012

The oncologist

Critical appraisal of translational research models for suitability in performance assessment of cancer centers.

25-12-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Risk of treatment-related esophageal cancer among breast cancer survivors.

01-12-2012

Pharmaceutical research

Model-based evaluation and optimization of cardiac monitoring protocols for adjuvant treatment of breast cancer with trastuzumab.

01-12-2012

Breast (Edinburgh, Scotland)

Additional value of the 70-gene signature and levels of ER and PR for the prediction of outcome in tamoxifen-treated ER-positive breast cancer.

01-12-2012

Human gene therapy

Rational design of DNA vaccines for the induction of human papillomavirus type 16 E6- and E7-specific cytotoxic T-cell responses.

01-12-2012

Trends in biochemical sciences

Switching Polo-like kinase-1 on and off in time and space.

01-12-2012

Cancer chemotherapy and pharmacology

Pharmacokinetics of eribulin mesylate in patients with solid tumors and hepatic impairment.

01-12-2012

Human brain mapping

Late effects of high-dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: converging results from multimodal magnetic resonance imaging.

01-12-2012

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Lack of tumor uptake of 131-I labeled rituximab in a patient with a CD20 positive lymphoma lesion.

01-12-2012

European journal of nuclear medicine and molecular imaging

Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy.

01-12-2012

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Radioguided occult lesion localisation (ROLL) in breast-conserving surgery after neoadjuvant chemotherapy.

01-12-2012

Proceedings of the National Academy of Sciences of the United States of America

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

27-11-2012

Cell

MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.

21-11-2012

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Efficacy of cognitive behavioral therapy and physical exercise in alleviating treatment-induced menopausal symptoms in patients with breast cancer: results of a randomized, controlled, multicenter trial.

20-11-2012

BMJ (Clinical research ed.)

Commentary: Substandard medicines are the priority for neglected tropical diseases.

14-11-2012

The Journal of biological chemistry

Intrinsic flexibility of ubiquitin on proliferating cell nuclear antigen (PCNA) in translesion synthesis.

09-11-2012

American journal of nuclear medicine and molecular imaging

Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist.

08-11-2012

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

Can adjuvant chemoradiotherapy replace extended lymph node dissection in gastric cancer?

07-11-2012

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

Treatment dilemmas in patients with synchronous colorectal liver metastases.

07-11-2012

Molecular pharmaceutics

Oral availability and brain penetration of the B-RAFV600E inhibitor vemurafenib can be enhanced by the P-GLYCOprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

05-11-2012

Clinical lung cancer

Diffuse reflectance spectroscopy: a new guidance tool for improvement of biopsy procedures in lung malignancies.

01-11-2012

Journal of the European Academy of Dermatology and Venereology : JEADV

Melanoma patients receive more follow-up care than current guideline recommendations: a study of 546 patients from the general Dutch population.

01-11-2012

Clinical pharmacology and therapeutics

Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification.

01-11-2012

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling.

The cancer antigenome.

Sensitive method for plasma and tumor Ko143 quantification using reversed-phase high-performance liquid chromatography and fluorescence detection.

Quantitative determination of capecitabine and its six metabolites in human plasma using liquid chromatography coupled to electrospray tandem mass spectrometry.

Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS

Directional interpolation for motion weighted 4D cone-beam CT reconstruction.

The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.

Development of a hypersensitive periodate-cleavable amino acid that is methionine- and disulfide-compatible and its application in MHC exchange reagents for T cell characterisation.

Spatiotemporal analysis of organelle and macromolecular complex inheritance.

Effect of diabetes on endometrial cancer recurrence and survival.

Phase I study of lonafarnib (SCH66336) in combination with trastuzumab plus paclitaxel in Her2/neu overexpressing breast cancer: EORTC study 16023.

Optical sensing for tumor detection in the liver.

Diffuse reflectance spectroscopy: towards clinical application in breast cancer.

Standard-dose tegafur-uracil (UFT) is not a safe alternative in partial dihydropyrimidine dehydrogenase-deficient patients.

Development of an oral solid dispersion formulation for use in low-dose metronomic chemotherapy of paclitaxel.

Required target margins for image-guided lung SBRT: Assessment of target position intrafraction and correction residuals.

Prognostication and prediction using gene expression profiling in oesophageal cancer.

MAPK uncouples cell cycle progression from cell spreading and cytoskeletal organization in cycling cells.

SERPINA6, BEX1, AGTR1, SLC26A3, and LAPTM4B are markers of resistance to neoadjuvant chemotherapy in HER2-negative breast cancer.

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

Relating acute esophagitis to radiotherapy dose using FDG-PET in concurrent chemo-radiotherapy for locally advanced non-small cell lung cancer.

Structure-function relationships of autotaxin, a secreted lysophospholipase D.

A preclinical mouse model of invasive lobular breast cancer metastasis.

Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.

Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration.

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.

Critical appraisal of translational research models for suitability in performance assessment of cancer centers.

Risk of treatment-related esophageal cancer among breast cancer survivors.

Model-based evaluation and optimization of cardiac monitoring protocols for adjuvant treatment of breast cancer with trastuzumab.

Additional value of the 70-gene signature and levels of ER and PR for the prediction of outcome in tamoxifen-treated ER-positive breast cancer.

Rational design of DNA vaccines for the induction of human papillomavirus type 16 E6- and E7-specific cytotoxic T-cell responses.

Switching Polo-like kinase-1 on and off in time and space.

Pharmacokinetics of eribulin mesylate in patients with solid tumors and hepatic impairment.

Late effects of high-dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: converging results from multimodal magnetic resonance imaging.

Lack of tumor uptake of 131-I labeled rituximab in a patient with a CD20 positive lymphoma lesion.

Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy.

Radioguided occult lesion localisation (ROLL) in breast-conserving surgery after neoadjuvant chemotherapy.

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.

Efficacy of cognitive behavioral therapy and physical exercise in alleviating treatment-induced menopausal symptoms in patients with breast cancer: results of a randomized, controlled, multicenter trial.

Commentary: Substandard medicines are the priority for neglected tropical diseases.

Intrinsic flexibility of ubiquitin on proliferating cell nuclear antigen (PCNA) in translesion synthesis.

Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist.

Can adjuvant chemoradiotherapy replace extended lymph node dissection in gastric cancer?

Treatment dilemmas in patients with synchronous colorectal liver metastases.

Oral availability and brain penetration of the B-RAFV600E inhibitor vemurafenib can be enhanced by the P-GLYCOprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

Diffuse reflectance spectroscopy: a new guidance tool for improvement of biopsy procedures in lung malignancies.

Melanoma patients receive more follow-up care than current guideline recommendations: a study of 546 patients from the general Dutch population.

Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification.

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