Publications

Genome biology

DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus.

28-05-2013

British journal of cancer

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers.

28-05-2013

Nature communications

Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein.

23-05-2013

PloS one

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

22-05-2013

PloS one

Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy.

22-05-2013

The breast journal

Paclitaxel, carboplatin, and trastuzumab in a neo-adjuvant regimen for HER2-positive breast cancer.

21-05-2013

The oncologist

Concise drug review: azacitidine and decitabine.

15-05-2013

The breast journal

Major changes in chemotherapy regimens administered to breast cancer patients during 2000-2008 in the Netherlands.

15-05-2013

International journal of cancer

P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.

15-05-2013

Cancer cell

In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.

13-05-2013

Nederlands tijdschrift voor geneeskunde

[Concomitant use of proton pump inhibitors and systemic corticosteroids].

10-05-2013

Proc Natl Acad Sci U S A: Proceedings of the National Academy of Siences of the United States of America

Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer

08-05-2013

Science (New York, N.Y.)

Heterogeneous differentiation patterns of individual CD8+ T cells.

03-05-2013

Nucleic acids research

A scale-space method for detecting recurrent DNA copy number changes with analytical false discovery rate control.

01-05-2013

The Journal of urology

FDG-positron emission tomography/computerized tomography for monitoring the response of pelvic lymph node metastasis to neoadjuvant chemotherapy for bladder cancer.

01-05-2013

International journal of radiation oncology, biology, physics

Hybrid registration of prostate and seminal vesicles for image guided radiation therapy.

01-05-2013

Gynecologic oncology

Follow-up practice in endometrial cancer and the association with patient and hospital characteristics: a study from the population-based PROFILES registry.

01-05-2013

CNS oncology

Targeting core (mutated) pathways of high-grade gliomas: challenges of intrinsic resistance and drug efflux.

01-05-2013

European journal of cancer (Oxford, England : 1990)

Sildenafil is not a useful modulator of ABCB1 and ABCG2 mediated drug resistance in vivo.

01-05-2013

Molecular pharmacology

Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure.

01-05-2013

Lung cancer (Amsterdam, Netherlands)

Improved identification of peripheral lung tumors by using diffuse reflectance and fluorescence spectroscopy.

01-05-2013

Journal of cell science

UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway.

01-05-2013

European journal of cancer (Oxford, England : 1990)

Quantifying fatigue in (long-term) colorectal cancer survivors: a study from the population-based patient reported outcomes following initial treatment and long term evaluation of survivorship registry.

01-05-2013

Communicative & integrative biology

Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation.

01-05-2013

Science (New York, N.Y.)

Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry.

26-04-2013

Frontiers in oncology

Loss of telomere protection: consequences and opportunities.

19-04-2013

The Journal of cell biology

Systematic dissection of dynein regulators in mitosis.

15-04-2013

Clinical cancer research : an official journal of the American Association for Cancer Research

Abcc4 together with abcb1 and abcg2 form a robust cooperative drug efflux system that restricts the brain entry of camptothecin analogues.

15-04-2013

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantification of cabazitaxel, its metabolite docetaxel and the determination of the demethylated metabolites RPR112698 and RPR123142 as docetaxel equivalents in human plasma by liquid chromatography-tandem mass spectrometry.

15-04-2013

Nature

Diverse and heritable lineage imprinting of early haematopoietic progenitors.

11-04-2013

The Journal of experimental medicine

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.

08-04-2013

Investigational new drugs

Eribulin mesylate pharmacokinetics in patients with solid tumors receiving repeated oral ketoconazole.

01-04-2013

Therapeutic drug monitoring

Quantification of sunitinib and N-desethyl sunitinib in human EDTA plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry: validation and application in routine therapeutic drug monitoring.

01-04-2013

Nature reviews. Nephrology

Cell-matrix adhesion of podocytes in physiology and disease.

01-04-2013

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

01-04-2013

Current opinion in immunology

Human cancer regression antigens.

01-04-2013

Endocrine-related cancer

Rising incidence, no change in survival and decreasing mortality from thyroid cancer in The Netherlands since 1989.

01-04-2013

Current opinion in genetics & development

Chromatin organization: form to function.

01-04-2013

Gynecologic oncology

The relationship of body mass index with quality of life among endometrial cancer survivors: a study from the population-based PROFILES registry.

01-04-2013

Molecular oncology

Mouse models for lung cancer.

01-04-2013

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Response to induction chemotherapy and surgery in non-organ confined bladder cancer: a single institution experience.

01-04-2013

Molecular oncology

Genetically engineered mouse models of PI3K signaling in breast cancer.

01-04-2013

The Netherlands journal of medicine

Recent advances towards the clinical application of DNA vaccines.

01-04-2013

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

01-04-2013

Biomedical chromatography : BMC

Method development and validation for the quantification of dasatinib, erlotinib, gefitinib, imatinib, lapatinib, nilotinib, sorafenib and sunitinib in human plasma by liquid chromatography coupled with tandem mass spectrometry.

01-04-2013

International journal of radiation oncology, biology, physics

Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study.

01-04-2013

Cell

Single-cell dynamics of genome-nuclear lamina interactions.

28-03-2013

Proceedings of the National Academy of Sciences of the United States of America

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis.

26-03-2013

International journal of radiation oncology, biology, physics

Targeted radiosensitization by the Chk1 inhibitor SAR-020106.

15-03-2013

The Journal of biological chemistry

Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.

15-03-2013

DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus.

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers.

Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein.

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy.

Paclitaxel, carboplatin, and trastuzumab in a neo-adjuvant regimen for HER2-positive breast cancer.

Concise drug review: azacitidine and decitabine.

Major changes in chemotherapy regimens administered to breast cancer patients during 2000-2008 in the Netherlands.

P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.

In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.

[Concomitant use of proton pump inhibitors and systemic corticosteroids].

Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer

Heterogeneous differentiation patterns of individual CD8+ T cells.

A scale-space method for detecting recurrent DNA copy number changes with analytical false discovery rate control.

FDG-positron emission tomography/computerized tomography for monitoring the response of pelvic lymph node metastasis to neoadjuvant chemotherapy for bladder cancer.

Hybrid registration of prostate and seminal vesicles for image guided radiation therapy.

Follow-up practice in endometrial cancer and the association with patient and hospital characteristics: a study from the population-based PROFILES registry.

Targeting core (mutated) pathways of high-grade gliomas: challenges of intrinsic resistance and drug efflux.

Sildenafil is not a useful modulator of ABCB1 and ABCG2 mediated drug resistance in vivo.

Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure.

Improved identification of peripheral lung tumors by using diffuse reflectance and fluorescence spectroscopy.

UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway.

Quantifying fatigue in (long-term) colorectal cancer survivors: a study from the population-based patient reported outcomes following initial treatment and long term evaluation of survivorship registry.

Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation.

Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry.

Loss of telomere protection: consequences and opportunities.

Systematic dissection of dynein regulators in mitosis.

Abcc4 together with abcb1 and abcg2 form a robust cooperative drug efflux system that restricts the brain entry of camptothecin analogues.

Quantification of cabazitaxel, its metabolite docetaxel and the determination of the demethylated metabolites RPR112698 and RPR123142 as docetaxel equivalents in human plasma by liquid chromatography-tandem mass spectrometry.

Diverse and heritable lineage imprinting of early haematopoietic progenitors.

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.

Eribulin mesylate pharmacokinetics in patients with solid tumors receiving repeated oral ketoconazole.

Quantification of sunitinib and N-desethyl sunitinib in human EDTA plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry: validation and application in routine therapeutic drug monitoring.

Cell-matrix adhesion of podocytes in physiology and disease.

Senescence: back to telomeres.

Human cancer regression antigens.

Rising incidence, no change in survival and decreasing mortality from thyroid cancer in The Netherlands since 1989.

Chromatin organization: form to function.

The relationship of body mass index with quality of life among endometrial cancer survivors: a study from the population-based PROFILES registry.

Mouse models for lung cancer.

Response to induction chemotherapy and surgery in non-organ confined bladder cancer: a single institution experience.

Genetically engineered mouse models of PI3K signaling in breast cancer.

Recent advances towards the clinical application of DNA vaccines.

Senescence: back to telomeres.

Method development and validation for the quantification of dasatinib, erlotinib, gefitinib, imatinib, lapatinib, nilotinib, sorafenib and sunitinib in human plasma by liquid chromatography coupled with tandem mass spectrometry.

Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study.

Single-cell dynamics of genome-nuclear lamina interactions.

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis.

Targeted radiosensitization by the Chk1 inhibitor SAR-020106.

Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.

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