Publications

Journal of clinical pharmacology

A phase 1 comparative pharmacokinetic and cardiac safety study of two intravenous formulations of CO-101 in patients with advanced solid tumors.

Practical neurology

Neurological immune-related adverse events of ipilimumab.

Molecular biology of the cell

Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis.

Oncogene

PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance.

25-07-2013

Proceedings of the National Academy of Sciences of the United States of America

Osteoclast precursors in murine bone marrow express CD27 and are impeded in osteoclast development by CD70 on activated immune cells.

23-07-2013

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Chemotherapy-induced neuropathy and its association with quality of life among 2- to 11-year colorectal cancer survivors: results from the population-based PROFILES registry.

20-07-2013

The EMBO journal

Break the loop, escape the cycle?

17-07-2013

J Exp Med.: The journal of experimental medicine

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

15-07-2013

Vaccine

Transposon leads to contamination of clinical pDNA vaccine.

11-07-2013

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Surgical treatment results of intestinal and diffuse type gastric cancer. Implications for a differentiated therapeutic approach?

Nature reviews. Genetics

Alternative cleavage and polyadenylation: extent, regulation and function.

European journal of cancer (Oxford, England : 1990)

Adrenocortical carcinoma: a population-based study on incidence and survival in the Netherlands since 1993.

The Journal of pathology

Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing.

Annals of surgical oncology

Early assessment of axillary response with ¹⁸F-FDG PET/CT during neoadjuvant chemotherapy in stage II-III breast cancer: implications for surgical management of the axilla.

Breast cancer research and treatment

Breast cancer subtyping by immunohistochemistry and histological grade outperforms breast cancer intrinsic subtypes in predicting neoadjuvant chemotherapy response.

European journal of endocrinology

Surgery for adrenocortical carcinoma in The Netherlands: analysis of the national cancer registry data.

British journal of clinical pharmacology

Optimizing drug development of anti-cancer drugs in children using modelling and simulation.

PloS one

Kindlin-1 regulates integrin dynamics and adhesion turnover.

19-06-2013

Nucleic Acids Res.

Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions

14-06-2013

Scientific reports

Defined lipid analogues induce transient channels to facilitate drug-membrane traversal and circumvent cancer therapy resistance.

07-06-2013

Nature

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.

06-06-2013

Cancer Research

Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling

03-06-2013

Nat Commun.: Nature communications

ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Prognostic parameters for acute esophagus toxicity in intensity modulated radiotherapy and concurrent chemotherapy for locally advanced non-small cell lung cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Vemurafenib as neoadjuvant treatment for unresectable regional metastatic melanoma.

Breast cancer research and treatment

CYP2C19 2 predicts substantial tamoxifen benefit in postmenopausal breast cancer patients randomized between adjuvant tamoxifen and no systemic treatment.

Psycho-oncology

Assessing the impact of cancer among Dutch non-Hodgkin lymphoma survivors compared with their American counterparts: a cross-national study.

Familial cancer

100 years Lynch syndrome: what have we learned about psychosocial issues?

Cancer

Population-based cancer registries for quality-of-life research: a work-in-progress resource for survivorship studies?

Antimicrobial agents and chemotherapy

Severe skin toxicity in pediatric oncology patients treated with voriconazole and concomitant methotrexate.

Cancer treatment reviews

Is combination therapy the next step to overcome resistance and reduce toxicities in melanoma?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Local dose-effect relations for lung perfusion post stereotactic body radiotherapy.

Oral oncology

Can extranodal spread in head and neck cancer be detected on MR imaging.

Cancer

The role of comprehensive cancer centers in survivorship care.

Clinical pharmacokinetics

Oral anticancer drugs: mechanisms of low bioavailability and strategies for improvement.

Breast cancer research and treatment

Platform comparisons for identification of breast cancers with a BRCA-like copy number profile.

Drug delivery and translational research

Pharmacokinetic evaluation of three oral formulations of docetaxel boosted with ritonavir: two single-drug formulations vs. a fixed-dose combination tablet.