Publications

International journal of radiation oncology, biology, physics

Thymidine analogues to assess microperfusion in human tumors.

15-07-2005

The Journal of biological chemistry

Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.

15-07-2005

Journal of pharmaceutical and biomedical analysis

LC-UV method development and validation for the investigational anticancer agent imexon and identification of its degradation products.

15-07-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Optimal locoregional treatment in gastric cancer.

10-07-2005

Rapid communications in mass spectrometry : RCM

Quantitative analysis of the farnesyl transferase inhibitor lonafarnib (Sarasartrade mark, SCH66336) in human plasma using high-performance liquid chromatography coupled with tandem mass spectrometry.

05-07-2005

Cancer immunology, immunotherapy : CII

A phase-II study of pegylated interferon alfa-2b for patients with metastatic renal cell carcinoma and removal of the primary tumor.

01-07-2005

Nature structural & molecular biology

Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.

01-07-2005

Head & neck

Hypoxia in head and neck cancer: how much, how important?

01-07-2005

Drug metabolism and disposition: the biological fate of chemicals

Midazolam and cyclosporin a metabolism in transgenic mice with liver-specific expression of human CYP3A4.

01-07-2005

European journal of cancer (Oxford, England : 1990)

Standardised FDG uptake: a prognostic factor for inoperable non-small cell lung cancer.

01-07-2005

International journal of radiation oncology, biology, physics

Pulmonary function changes after radiotherapy in non-small-cell lung cancer patients with long-term disease-free survival.

01-07-2005

Genome biology

Histone modifications: from genome-wide maps to functional insights.

18-06-2005

Cell

Stem cells for lung cancer?

17-06-2005

Cell

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

17-06-2005

Genes & development

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

15-06-2005

The Journal of biological chemistry

Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.

10-06-2005

The Journal of biological chemistry

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.

03-06-2005

Current opinion in immunology

CD27 and CD70 in T cell and B cell activation.

01-06-2005

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The prognostic significance of axillary lymph-node micrometastases in breast cancer patients.

01-06-2005

Current opinion in microbiology

Presenting antigen presentation in living cells using biophysical techniques.

01-06-2005

Nature genetics

Mapping of genetic and epigenetic regulatory networks using microarrays.

01-06-2005

European journal of cancer (Oxford, England : 1990)

Increased risk of breast cancer development after diagnosis of salivary gland tumour.

01-06-2005

Investigational new drugs

Semi-physiological model describing the hematological toxicity of the anti-cancer agent indisulam.

01-06-2005

Therapeutic drug monitoring

Sparse sampling design for therapeutic drug monitoring of sequentially administered cyclophosphamide, thiotepa, and carboplatin (CTC).

01-06-2005

Biomedical chromatography : BMC

Quantitative analysis of docetaxel in human plasma using liquid chromatography coupled with tandem mass spectrometry.

01-06-2005

Experimental lung research

Lung tumor location and lymphocyte infiltration in mice are genetically determined.

01-06-2005

Cancer cell

A functional approach to questions about life, death, and phosphorylation.

01-06-2005

Proceedings of the National Academy of Sciences of the United States of America

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.

24-05-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Changes in gene expression associated with response to neoadjuvant chemotherapy in breast cancer.

20-05-2005

Proceedings of the National Academy of Sciences of the United States of America

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

17-05-2005

American journal of epidemiology

Validity of self-reported causes of subfertility.

15-05-2005

The Journal of cell biology

Integrins control motile strategy through a Rho-cofilin pathway.

09-05-2005

The EMBO journal

PIP2 signaling in lipid domains: a critical re-evaluation.

04-05-2005

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology

Whole-genome views of chromatin structure.

04-05-2005

Journal of pharmaceutical sciences

Pharmaceutical development of a lyophilised dosage form for the investigational anticancer agent Imexon using dimethyl sulfoxide as solubilising and stabilising agent.

01-05-2005

Drug metabolism and disposition: the biological fate of chemicals

Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2).

01-05-2005

Molecular pharmacology

Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver.

01-05-2005

Cancer chemotherapy and pharmacology

Significant induction of cyclophosphamide and thiotepa metabolism by phenytoin.

01-05-2005

Pharmacological research

Hepatotoxicity and metabolism of trabectedin: a literature review.

01-05-2005

Molecular pharmacology

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

01-05-2005

Cancer chemotherapy and pharmacology

Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma.

01-05-2005

Oncogene

Getting in and out of mitosis with Polo-like kinase-1.

18-04-2005

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice

Detection of single nucleotide polymorphisms in the ABCG2 gene in a Dutch population.

09-04-2005

Cancer research

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients.

01-04-2005

Medical physics

Respiratory correlated cone beam CT.

01-04-2005

Genes & development

Mouse models for human lung cancer.

15-03-2005

Journal of cell science

Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice.

01-03-2005

Anti-cancer drugs

Effects of co-medicated drugs on cyclophosphamide bioactivation in human liver microsomes.

01-03-2005

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Compatibility and stability of the novel anti-cancer agent C1311 in infusion devices and its in vitro biocompatibility.

01-03-2005

Cancer chemotherapy and pharmacology

Phase I study of an oral formulation of irinotecan administered daily for 14 days every 3 weeks in patients with advanced solid tumours.

01-03-2005