Publications

Breast cancer research and treatment

Radiation- and anthracycline-induced cardiac toxicity and the influence of ErbB2 blocking agents.

Cell research

eRNAs reach the heart of transcription.

Breast (Edinburgh, Scotland)

Breast cancer in women at high risk: the role of rapid genetic testing for BRCA1 and -2 mutations and the consequences for treatment strategies.

Breast (Edinburgh, Scotland)

FDG PET/CT during neoadjuvant chemotherapy may predict response in ER-positive/HER2-negative and triple negative, but not in HER2-positive breast cancer.

Breast (Edinburgh, Scotland)

Scalp cooling to prevent alopecia after chemotherapy can be considered safe in patients with breast cancer.

Diabetic medicine : a journal of the British Diabetic Association

Diminishing differences in treatment between patients with colorectal cancer with and without diabetes: a population-based study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Microscopic disease extensions as a risk factor for loco-regional recurrence of NSCLC after SBRT.

Cancer treatment reviews

Effect of inhibition of the FGFR-MAPK signaling pathway on the development of ocular toxicities.

Thyroid : official journal of the American Thyroid Association

Fatigue among short- and long-term thyroid cancer survivors: results from the population-based PROFILES registry.

Nature methods

hiFRET: some tailwind for FRET resolves weak protein interactions.

European journal of oncology nursing : the official journal of European Oncology Nursing Society

Impact of scalp cooling on chemotherapy-induced alopecia, wig use and hair growth of patients with cancer.

Cancer discovery

A high-throughput functional complementation assay for classification of BRCA1 missense variants.

Pharmacological research

P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387.

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy and safety of ipilimumab in metastatic melanoma patients surviving more than 2 years following treatment in a phase III trial (MDX010-20).

Molecular oncology

A gene signature for late distant metastasis in breast cancer identifies a potential mechanism of late recurrences.

Investigational new drugs

Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA.

Critical reviews in oncology/hematology

Late effects of adjuvant chemotherapy for adult onset non-CNS cancer; cognitive impairment, brain structure and risk of dementia.

Methods in molecular biology (Clifton, N.J.)

Detecting cAMP with an EPAC-based FRET sensor in single living cells.

21-09-2013

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Stomach cancer risk after treatment for hodgkin lymphoma.

20-09-2013

Oncogene

Genetic instability: tipping the balance.

19-09-2013

Cell cycle (Georgetown, Tex.)

TGF-β: an emerging player in drug resistance.

Journal of immunology (Baltimore, Md. : 1950)

CD8+ T cells produce the chemokine CXCL10 in response to CD27/CD70 costimulation to promote generation of the CD8+ effector T cell pool.

Journal of immunology (Baltimore, Md. : 1950)

Blockade of TGF-β signaling greatly enhances the efficacy of TCR gene therapy of cancer.

Rapid communications in mass spectrometry : RCM

Quantification of docetaxel and its metabolites in human plasma by liquid chromatography/tandem mass spectrometry.

Nature

The pluripotent genome in three dimensions is shaped around pluripotency factors.

12-09-2013

International journal of pharmaceutics

Long term stability of lyophilized plasmid DNA pDERMATT.

10-09-2013

Stem Cells (Dayton, Ohio)

Somatic loss of p53 leads to stem/progenitor cell amplification in both mammary epithelial compartments, basal and luminal

International journal of cancer

Dual mTORC1 and mTORC2 inhibitor Palomid 529 penetrates the blood-brain barrier without restriction by ABCB1 and ABCG2.

Nucleic acids research

Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation.

The Journal of investigative dermatology

Kindlin-1 mutant zebrafish as an in vivo model system to study adhesion mechanisms in the epidermis.

Stem cells (Dayton, Ohio)

Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool.

Nucleic acids research

A versatile microsatellite instability reporter system in human cells.

Gynecologic oncology

Phase I dose-escalation study and population pharmacokinetic analysis of fixed dose rate gemcitabine plus carboplatin as second-line therapy in patients with ovarian cancer.

The Journal of pharmacology and experimental therapeutics

Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) gene dosage on plasma pharmacokinetics and brain accumulation of dasatinib, sorafenib, and sunitinib.

EJC supplements : EJC : official journal of EORTC, European Organization for Research and Treatment of Cancer ... [et al.]

Immunotherapy of melanoma.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Health care use among endometrial cancer survivors: a study from PROFILES, a population-based survivorship registry.

European urology

Early wound complications after inguinal lymphadenectomy in penile cancer: a historical cohort study and risk-factor analysis.

British journal of clinical pharmacology

Population pharmacokinetic-pharmacodynamic analysis for eribulin mesilate-associated neutropenia.

Journal of cancer survivorship : research and practice

Depressive symptoms are a risk factor for all-cause mortality: results from a prospective population-based study among 3,080 cancer survivors from the PROFILES registry.

EJC supplements : EJC : official journal of EORTC, European Organization for Research and Treatment of Cancer ... [et al.]

Chemotherapy-related changes in cognitive functioning.