Publications

Annals of oncology : official journal of the European Society for Medical Oncology

Long-term responders and survivors on pazopanib for advanced soft tissue sarcomas: subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072.

Current opinion in oncology

The perspective of immunotherapy: new molecules and new mechanisms of action in immune modulation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dose-response relationship with clinical outcome for lung stereotactic body radiotherapy (SBRT) delivered via online image guidance.

International journal of radiation oncology, biology, physics

Performance of a nomogram predicting disease-specific survival after an R0 resection for gastric cancer in patients receiving postoperative chemoradiation therapy.

International journal of radiation oncology, biology, physics

Combined recipe for clinical target volume and planning target volume margins.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Mid-ventilation based PTV margins in Stereotactic Body Radiotherapy (SBRT): a clinical evaluation.

The Journal of molecular diagnostics : JMD

MammaPrint molecular diagnostics on formalin-fixed, paraffin-embedded tissue.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Treatment adherence in concurrent chemoradiation in patients with locally advanced non-small cell lung carcinoma: results of daily intravenous prehydration.

Cell reports

Determining lineage pathways from cellular barcoding experiments.

27-02-2014

PloS one

Breast cancer subtype specific classifiers of response to neoadjuvant chemotherapy do not outperform classifiers trained on all subtypes.

22-02-2014

ACS chemical biology

Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection.

21-02-2014

Cell cycle (Georgetown, Tex.)

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

21-02-2014

British journal of cancer

Chronic fatigue in Hodgkin lymphoma survivors and associations with anxiety, depression and comorbidity.

18-02-2014

British journal of cancer

The impact of organisational external peer review on colorectal cancer treatment and survival in the Netherlands.

18-02-2014

British journal of cancer

Impact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial.

18-02-2014

Nature communications

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.

13-02-2014

Breast cancer research and treatment

Tamoxifen dose and serum concentrations of tamoxifen and six of its metabolites in routine clinical outpatient care.

Breast (Edinburgh, Scotland)

Time trends and inter-hospital variation in treatment and axillary staging of patients with ductal carcinoma in situ of the breast in the era of screening in Southern Netherlands.

World journal of urology

Do targeted agents offer clinical benefit as presurgical therapy?

Journal of pharmaceutical sciences

Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling.

Biomedical chromatography : BMC

Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.

Molecular cancer therapeutics

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

Current opinion in genetics & development

Finding effective cancer therapies through loss of function genetic screens.

EMBO reports

RBR E3-ligases at work.

Breast cancer research and treatment

Long-term impact of the 70-gene signature on breast cancer outcome.

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibitors?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study.

Journal of medical genetics

Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations.

EMBO molecular medicine

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

Breast cancer research and treatment

Mammographic screening detects low-risk tumor biology breast cancers.

Annals of surgical oncology

Reply to "Anti-cytokeratin CAM5.2 recognized CK8 mainly, but not CK18: comment on 'Early assessment of axillary response with 18F-FDG PET/CT during neoadjuvant chemotherapy in stage II-III breast cancer: implications for surgical management of the axilla. Ann Surg Oncol. 2013;20(7):2227-35'".

Nature reviews. Urology

Urological complications after treatment of cervical cancer.

European journal of radiology

Avoiding preoperative breast MRI when conventional imaging is sufficient to stage patients eligible for breast conserving therapy.

Cell death and differentiation

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential.

Nederlands tijdschrift voor geneeskunde

[Biobanks and the return of results to donors].

30-01-2014

Oncogene

Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling.

30-01-2014

BMC cancer

The Nightingale study: rationale, study design and baseline characteristics of a prospective cohort study on shift work and breast cancer risk among nurses.

29-01-2014

Scientific reports

The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation.

24-01-2014

PloS one

Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101).

15-01-2014

BMC cancer

The efficacy of a standardized questionnaire in facilitating personalized communication about problems encountered in cancer genetic counseling: design of a randomized controlled trial.

15-01-2014

Journal of immunology (Baltimore, Md. : 1950)

HLA micropolymorphisms strongly affect peptide-MHC multimer-based monitoring of antigen-specific CD8+ T cell responses.

15-01-2014

Frontiers in genetics

Current composite-feature classification methods do not outperform simple single-genes classifiers in breast cancer prognosis.

07-01-2014

Oral oncology

The influence of nodal yield in neck dissections on lymph node ratio in head and neck cancer.

Nature genetics

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Urology

Induction chemotherapy followed by surgery in node positive bladder cancer.

International journal of radiation oncology, biology, physics

Alpha/beta ratio for normal lung tissue as estimated from lung cancer patients treated with stereotactic body and conventionally fractionated radiation therapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Gastric cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Urologic oncology

Ensuring comprehensive assessment of urinary problems in prostate cancer through patient-physician concordance.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Additional weekly Cetuximab to concurrent chemoradiotherapy in locally advanced non-small cell lung carcinoma: efficacy and safety outcomes of a randomized, multi-center phase II study investigating.