Publications

Biomedical chromatography : BMC

Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.

Molecular cancer therapeutics

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

Current opinion in genetics & development

Finding effective cancer therapies through loss of function genetic screens.

EMBO reports

RBR E3-ligases at work.

Breast cancer research and treatment

Long-term impact of the 70-gene signature on breast cancer outcome.

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibitors?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study.

Journal of medical genetics

Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations.

EMBO molecular medicine

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

Breast cancer research and treatment

Mammographic screening detects low-risk tumor biology breast cancers.

Annals of surgical oncology

Reply to "Anti-cytokeratin CAM5.2 recognized CK8 mainly, but not CK18: comment on 'Early assessment of axillary response with 18F-FDG PET/CT during neoadjuvant chemotherapy in stage II-III breast cancer: implications for surgical management of the axilla. Ann Surg Oncol. 2013;20(7):2227-35'".

Nature reviews. Urology

Urological complications after treatment of cervical cancer.

European journal of radiology

Avoiding preoperative breast MRI when conventional imaging is sufficient to stage patients eligible for breast conserving therapy.

Cell death and differentiation

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential.

Nederlands tijdschrift voor geneeskunde

[Biobanks and the return of results to donors].

30-01-2014

Oncogene

Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling.

30-01-2014

BMC cancer

The Nightingale study: rationale, study design and baseline characteristics of a prospective cohort study on shift work and breast cancer risk among nurses.

29-01-2014

Scientific reports

The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation.

24-01-2014

PloS one

Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101).

15-01-2014

BMC cancer

The efficacy of a standardized questionnaire in facilitating personalized communication about problems encountered in cancer genetic counseling: design of a randomized controlled trial.

15-01-2014

Journal of immunology (Baltimore, Md. : 1950)

HLA micropolymorphisms strongly affect peptide-MHC multimer-based monitoring of antigen-specific CD8+ T cell responses.

15-01-2014

Frontiers in genetics

Current composite-feature classification methods do not outperform simple single-genes classifiers in breast cancer prognosis.

07-01-2014

Oral oncology

The influence of nodal yield in neck dissections on lymph node ratio in head and neck cancer.

Nature genetics

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Urology

Induction chemotherapy followed by surgery in node positive bladder cancer.

International journal of radiation oncology, biology, physics

Alpha/beta ratio for normal lung tissue as estimated from lung cancer patients treated with stereotactic body and conventionally fractionated radiation therapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Gastric cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Urologic oncology

Ensuring comprehensive assessment of urinary problems in prostate cancer through patient-physician concordance.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Additional weekly Cetuximab to concurrent chemoradiotherapy in locally advanced non-small cell lung carcinoma: efficacy and safety outcomes of a randomized, multi-center phase II study investigating.

Acta oncologica (Stockholm, Sweden)

Cost-effectiveness analysis of scalp cooling to reduce chemotherapy-induced alopecia.

Health technology assessment (Winchester, England)

The clinical effectiveness and cost-effectiveness of ablative therapies in the management of liver metastases: systematic review and economic evaluation.

Journal of pharmaceutical and biomedical analysis

Development and validation of a high-performance liquid chromatography-tandem mass spectrometry assay quantifying vemurafenib in human plasma.

The Journal of investigative dermatology

Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of CD151.

Immunological reviews

TCR repertoires of intratumoral T-cell subsets.

European journal of nuclear medicine and molecular imaging

Sequential (18)F-FDG PET/CT for early prediction of complete pathological response in breast and axilla during neoadjuvant chemotherapy.

BMC cancer

Hot flashes are not predictive for serum concentrations of tamoxifen and its metabolites.

28-12-2013

Cell reports

A UV-induced genetic network links the RSC complex to nucleotide excision repair and shows dose-dependent rewiring.

26-12-2013

OncoTargets and therapy

Synchronous BRAF(V600E) and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity.

19-12-2013

Translational psychiatry

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

17-12-2013

British journal of cancer

Neoadjuvant chemotherapy adaptation and serial MRI response monitoring in ER-positive HER2-negative breast cancer.

10-12-2013

Nature communications

Ribosome profiling reveals features of normal and disease-associated mitochondrial translation.

05-12-2013

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Registration accuracy and image quality of time averaged mid-position CT scans for liver SBRT.

Cell calcium

TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells.

European journal of cancer (Oxford, England : 1990)

β-Blocker use and all-cause mortality of melanoma patients: results from a population-based Dutch cohort study.

European journal of cancer (Oxford, England : 1990)

Prospective cost-effectiveness analysis of genomic profiling in breast cancer.

BMC cancer

Severe pan-uveitis in a patient treated with vemurafenib for metastatic melanoma.

European journal of clinical pharmacology

The effect of seasonal variation and secretion of sunitinib in sweat on the development of hand-foot syndrome.

Annals of surgical oncology

Selection of patients for hepatic surgery of colorectal cancer liver metastasis based on genomic aberrations.

Brain imaging and behavior

Functional MRI studies in non-CNS cancers.