Publications

Cell

A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia.

Cell reports

Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.

Cell reports

Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells.

Methods in molecular biology (Clifton, N.J.)

Intradermal vaccination by DNA tattooing.

Nature

Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.

03-04-2014

The Lancet. Oncology

Vemurafenib in patients with BRAF(V600) mutated metastatic melanoma: an open-label, multicentre, safety study.

PLoS genetics

Genetic predisposition to in situ and invasive lobular carcinoma of the breast.

Journal of the International Neuropsychological Society : JINS

Systemically treated breast cancer patients and controls: an evaluation of the presence of noncredible performance.

Clinical pharmacokinetics

Practical guidelines for therapeutic drug monitoring of anticancer tyrosine kinase inhibitors: focus on the pharmacokinetic targets.

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the light sensitive survivin suppressant sepantronium bromide (YM155) in mouse plasma.

Journal of genetic counseling

Specific psychosocial issues of individuals undergoing genetic counseling for cancer - a literature review.

PLoS genetics

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers.

European journal of epidemiology

Leukemia and brain tumors among children after radiation exposure from CT scans: design and methodological opportunities of the Dutch Pediatric CT Study.

Annals of oncology : official journal of the European Society for Medical Oncology

Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Trends in immunology

Single cell behavior in T cell differentiation.

Nature structural & molecular biology

Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.

Clinical pharmacology and therapeutics

Herb-drug interactions in oncology.

Cancer biology & therapy

Lower mitotic activity in BRCA1/2-associated primary breast cancers occurring after risk-reducing salpingo-oophorectomy.

Annals of surgical oncology

The prognostic significance of an R1 resection in gastric cancer patients treated with adjuvant chemoradiotherapy.

Diabetes & metabolism

Colorectal cancer, diabetes and survival: epidemiological insights.

Translational oncology

Monitoring of tumor response to Cisplatin using optical spectroscopy.

Proceedings of the National Academy of Sciences of the United States of America

Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma.

Bioanalysis

Quantification of taxanes in biological matrices: a review of bioanalytical assays and recommendations for development of new assays.

Cancer discovery

Unlikely suspects identified in neuroblastoma conspiracy.

The Lancet. Oncology

Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.

PLoS genetics

Chromatin landscapes of retroviral and transposon integration profiles.

European journal of cancer (Oxford, England : 1990)

Risk estimations and treatment decisions in early stage breast cancer: agreement among oncologists and the impact of the 70-gene signature.

BioMed research international

Semiphysiological versus empirical modelling of the population pharmacokinetics of free and total cefazolin during pregnancy.

29-03-2014

Molecular cell

Uncovering SUMOylation dynamics during cell-cycle progression reveals FoxM1 as a key mitotic SUMO target protein.

20-03-2014

International journal of cancer

Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

15-03-2014

Molecular cell

Assessing kinetics from fixed cells reveals activation of the mitotic entry network at the S/G2 transition.

06-03-2014

Nature

Cancer: Inflammation lights the way to metastasis.

06-03-2014

Human brain mapping

Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy.

European journal of cancer (Oxford, England : 1990)

Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983.

Cancer letters

Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes.

The Lancet. Oncology

Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study.

Journal of pharmaceutical and biomedical analysis

Quantitative determination of azacitidine triphosphate in peripheral blood mononuclear cells using liquid chromatography coupled with high-resolution mass spectrometry.

European urology

A hybrid radioactive and fluorescent tracer for sentinel node biopsy in penile carcinoma as a potential replacement for blue dye.

Clinical pharmacokinetics

Predictive value of CYP3A and ABCB1 phenotyping probes for the pharmacokinetics of sunitinib: the ClearSun study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Association between metformin use and mortality in patients with prostate cancer: explained by confounding by indication?

Molecular pharmacology

Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.

Medical physics

Multi-institutional dosimetric and geometric commissioning of image-guided small animal irradiators.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The course of health-related quality of life in head and neck cancer patients treated with chemoradiation: a prospective cohort study.

Annals of oncology : official journal of the European Society for Medical Oncology

Long-term responders and survivors on pazopanib for advanced soft tissue sarcomas: subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072.

Current opinion in oncology

The perspective of immunotherapy: new molecules and new mechanisms of action in immune modulation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dose-response relationship with clinical outcome for lung stereotactic body radiotherapy (SBRT) delivered via online image guidance.

International journal of radiation oncology, biology, physics

Performance of a nomogram predicting disease-specific survival after an R0 resection for gastric cancer in patients receiving postoperative chemoradiation therapy.

International journal of radiation oncology, biology, physics

Combined recipe for clinical target volume and planning target volume margins.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Mid-ventilation based PTV margins in Stereotactic Body Radiotherapy (SBRT): a clinical evaluation.