Publications

Anti-cancer drugs

Cellular and clinical pharmacology of the taxanes docetaxel and paclitaxel--a review.

Cancer discovery

Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.

Oncogene

Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent.

Cancer immunology, immunotherapy : CII

Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma.

Lasers in medical science

Optical biopsy of epithelial cancers by optical coherence tomography (OCT).

Oncogene

The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.

24-04-2014

Physics in medicine and biology

Automatic detection system for multiple region of interest registration to account for posture changes in head and neck radiotherapy.

21-04-2014

Nature

Domains of genome-wide gene expression dysregulation in Down's syndrome.

17-04-2014

Current biology : CB

Dopaminergic modulation of cAMP drives nonlinear plasticity across the Drosophila mushroom body lobes.

14-04-2014

Nucleus (Austin, Tex.)

Stochastic genome-nuclear lamina interactions: modulating roles of Lamin A and BAF.

11-04-2014

Oncogene

Dual roles of hemidesmosomal proteins in the pancreatic epithelium: the phosphoinositide 3-kinase decides.

Cell

A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia.

Cell reports

Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.

Cell reports

Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells.

Methods in molecular biology (Clifton, N.J.)

Intradermal vaccination by DNA tattooing.

Nature

Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.

03-04-2014

The Lancet. Oncology

Vemurafenib in patients with BRAF(V600) mutated metastatic melanoma: an open-label, multicentre, safety study.

PLoS genetics

Genetic predisposition to in situ and invasive lobular carcinoma of the breast.

Journal of the International Neuropsychological Society : JINS

Systemically treated breast cancer patients and controls: an evaluation of the presence of noncredible performance.

Clinical pharmacokinetics

Practical guidelines for therapeutic drug monitoring of anticancer tyrosine kinase inhibitors: focus on the pharmacokinetic targets.

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the light sensitive survivin suppressant sepantronium bromide (YM155) in mouse plasma.

Journal of genetic counseling

Specific psychosocial issues of individuals undergoing genetic counseling for cancer - a literature review.

PLoS genetics

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers.

European journal of epidemiology

Leukemia and brain tumors among children after radiation exposure from CT scans: design and methodological opportunities of the Dutch Pediatric CT Study.

Annals of oncology : official journal of the European Society for Medical Oncology

Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Trends in immunology

Single cell behavior in T cell differentiation.

Nature structural & molecular biology

Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.

Clinical pharmacology and therapeutics

Herb-drug interactions in oncology.

Cancer biology & therapy

Lower mitotic activity in BRCA1/2-associated primary breast cancers occurring after risk-reducing salpingo-oophorectomy.

Annals of surgical oncology

The prognostic significance of an R1 resection in gastric cancer patients treated with adjuvant chemoradiotherapy.

Diabetes & metabolism

Colorectal cancer, diabetes and survival: epidemiological insights.

Translational oncology

Monitoring of tumor response to Cisplatin using optical spectroscopy.

Proceedings of the National Academy of Sciences of the United States of America

Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma.

Bioanalysis

Quantification of taxanes in biological matrices: a review of bioanalytical assays and recommendations for development of new assays.

Cancer discovery

Unlikely suspects identified in neuroblastoma conspiracy.

The Lancet. Oncology

Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.

PLoS genetics

Chromatin landscapes of retroviral and transposon integration profiles.

European journal of cancer (Oxford, England : 1990)

Risk estimations and treatment decisions in early stage breast cancer: agreement among oncologists and the impact of the 70-gene signature.

BioMed research international

Semiphysiological versus empirical modelling of the population pharmacokinetics of free and total cefazolin during pregnancy.

29-03-2014

Molecular cell

Uncovering SUMOylation dynamics during cell-cycle progression reveals FoxM1 as a key mitotic SUMO target protein.

20-03-2014

International journal of cancer

Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

15-03-2014

Molecular cell

Assessing kinetics from fixed cells reveals activation of the mitotic entry network at the S/G2 transition.

06-03-2014

Nature

Cancer: Inflammation lights the way to metastasis.

06-03-2014

Human brain mapping

Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy.

European journal of cancer (Oxford, England : 1990)

Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983.

Cancer letters

Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes.

The Lancet. Oncology

Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study.

Journal of pharmaceutical and biomedical analysis

Quantitative determination of azacitidine triphosphate in peripheral blood mononuclear cells using liquid chromatography coupled with high-resolution mass spectrometry.

European urology

A hybrid radioactive and fluorescent tracer for sentinel node biopsy in penile carcinoma as a potential replacement for blue dye.