Publications

PloS one

Breast cancer subtype specific classifiers of response to neoadjuvant chemotherapy do not outperform classifiers trained on all subtypes.

22-02-2014

ACS chemical biology

Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection.

21-02-2014

Cell cycle (Georgetown, Tex.)

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

21-02-2014

British journal of cancer

Chronic fatigue in Hodgkin lymphoma survivors and associations with anxiety, depression and comorbidity.

18-02-2014

British journal of cancer

The impact of organisational external peer review on colorectal cancer treatment and survival in the Netherlands.

18-02-2014

British journal of cancer

Impact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial.

18-02-2014

Nature communications

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.

13-02-2014

Breast cancer research and treatment

Tamoxifen dose and serum concentrations of tamoxifen and six of its metabolites in routine clinical outpatient care.

01-02-2014

Breast (Edinburgh, Scotland)

Time trends and inter-hospital variation in treatment and axillary staging of patients with ductal carcinoma in situ of the breast in the era of screening in Southern Netherlands.

01-02-2014

World journal of urology

Do targeted agents offer clinical benefit as presurgical therapy?

01-02-2014

Journal of pharmaceutical sciences

Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling.

01-02-2014

Biomedical chromatography : BMC

Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.

01-02-2014

Molecular cancer therapeutics

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

01-02-2014

Current opinion in genetics & development

Finding effective cancer therapies through loss of function genetic screens.

01-02-2014

EMBO reports

RBR E3-ligases at work.

01-02-2014

Breast cancer research and treatment

Long-term impact of the 70-gene signature on breast cancer outcome.

01-02-2014

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibitors?

01-02-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study.

01-02-2014

Journal of medical genetics

Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations.

01-02-2014

EMBO molecular medicine

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

01-02-2014

Breast cancer research and treatment

Mammographic screening detects low-risk tumor biology breast cancers.

01-02-2014

Annals of surgical oncology

Reply to "Anti-cytokeratin CAM5.2 recognized CK8 mainly, but not CK18: comment on 'Early assessment of axillary response with 18F-FDG PET/CT during neoadjuvant chemotherapy in stage II-III breast cancer: implications for surgical management of the axilla. Ann Surg Oncol. 2013;20(7):2227-35'".

01-02-2014

Nature reviews. Urology

Urological complications after treatment of cervical cancer.

01-02-2014

European journal of radiology

Avoiding preoperative breast MRI when conventional imaging is sufficient to stage patients eligible for breast conserving therapy.

01-02-2014

Cell death and differentiation

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential.

01-02-2014

Nederlands tijdschrift voor geneeskunde

[Biobanks and the return of results to donors].

30-01-2014

Oncogene

Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling.

30-01-2014

BMC cancer

The Nightingale study: rationale, study design and baseline characteristics of a prospective cohort study on shift work and breast cancer risk among nurses.

29-01-2014

Scientific reports

The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation.

24-01-2014

PloS one

Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101).

15-01-2014

BMC cancer

The efficacy of a standardized questionnaire in facilitating personalized communication about problems encountered in cancer genetic counseling: design of a randomized controlled trial.

15-01-2014

Journal of immunology (Baltimore, Md. : 1950)

HLA micropolymorphisms strongly affect peptide-MHC multimer-based monitoring of antigen-specific CD8+ T cell responses.

15-01-2014

Frontiers in genetics

Current composite-feature classification methods do not outperform simple single-genes classifiers in breast cancer prognosis.

07-01-2014

Oral oncology

The influence of nodal yield in neck dissections on lymph node ratio in head and neck cancer.

01-01-2014

Nature genetics

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

01-01-2014

Urology

Induction chemotherapy followed by surgery in node positive bladder cancer.

01-01-2014

International journal of radiation oncology, biology, physics

Alpha/beta ratio for normal lung tissue as estimated from lung cancer patients treated with stereotactic body and conventionally fractionated radiation therapy.

01-01-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Gastric cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

01-01-2014

Urologic oncology

Ensuring comprehensive assessment of urinary problems in prostate cancer through patient-physician concordance.

01-01-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Additional weekly Cetuximab to concurrent chemoradiotherapy in locally advanced non-small cell lung carcinoma: efficacy and safety outcomes of a randomized, multi-center phase II study investigating.

01-01-2014

Acta oncologica (Stockholm, Sweden)

Cost-effectiveness analysis of scalp cooling to reduce chemotherapy-induced alopecia.

01-01-2014

Health technology assessment (Winchester, England)

The clinical effectiveness and cost-effectiveness of ablative therapies in the management of liver metastases: systematic review and economic evaluation.

01-01-2014

Journal of pharmaceutical and biomedical analysis

Development and validation of a high-performance liquid chromatography-tandem mass spectrometry assay quantifying vemurafenib in human plasma.

01-01-2014

The Journal of investigative dermatology

Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of CD151.

01-01-2014

Immunological reviews

TCR repertoires of intratumoral T-cell subsets.

01-01-2014

European journal of nuclear medicine and molecular imaging

Sequential (18)F-FDG PET/CT for early prediction of complete pathological response in breast and axilla during neoadjuvant chemotherapy.

01-01-2014

BMC cancer

Hot flashes are not predictive for serum concentrations of tamoxifen and its metabolites.

28-12-2013

Cell reports

A UV-induced genetic network links the RSC complex to nucleotide excision repair and shows dose-dependent rewiring.

26-12-2013

OncoTargets and therapy

Synchronous BRAF(V600E) and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity.

19-12-2013

Translational psychiatry

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

17-12-2013

Breast cancer subtype specific classifiers of response to neoadjuvant chemotherapy do not outperform classifiers trained on all subtypes.

Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection.

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

Chronic fatigue in Hodgkin lymphoma survivors and associations with anxiety, depression and comorbidity.

The impact of organisational external peer review on colorectal cancer treatment and survival in the Netherlands.

Impact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial.

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.

Tamoxifen dose and serum concentrations of tamoxifen and six of its metabolites in routine clinical outpatient care.

Time trends and inter-hospital variation in treatment and axillary staging of patients with ductal carcinoma in situ of the breast in the era of screening in Southern Netherlands.

Do targeted agents offer clinical benefit as presurgical therapy?

Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling.

Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

Finding effective cancer therapies through loss of function genetic screens.

RBR E3-ligases at work.

Long-term impact of the 70-gene signature on breast cancer outcome.

Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibitors?

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study.

Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations.

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

Mammographic screening detects low-risk tumor biology breast cancers.

Reply to "Anti-cytokeratin CAM5.2 recognized CK8 mainly, but not CK18: comment on 'Early assessment of axillary response with 18F-FDG PET/CT during neoadjuvant chemotherapy in stage II-III breast cancer: implications for surgical management of the axilla. Ann Surg Oncol. 2013;20(7):2227-35'".

Urological complications after treatment of cervical cancer.

Avoiding preoperative breast MRI when conventional imaging is sufficient to stage patients eligible for breast conserving therapy.

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential.

[Biobanks and the return of results to donors].

Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling.

The Nightingale study: rationale, study design and baseline characteristics of a prospective cohort study on shift work and breast cancer risk among nurses.

The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation.

Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101).

The efficacy of a standardized questionnaire in facilitating personalized communication about problems encountered in cancer genetic counseling: design of a randomized controlled trial.

HLA micropolymorphisms strongly affect peptide-MHC multimer-based monitoring of antigen-specific CD8+ T cell responses.

Current composite-feature classification methods do not outperform simple single-genes classifiers in breast cancer prognosis.

The influence of nodal yield in neck dissections on lymph node ratio in head and neck cancer.

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Induction chemotherapy followed by surgery in node positive bladder cancer.

Alpha/beta ratio for normal lung tissue as estimated from lung cancer patients treated with stereotactic body and conventionally fractionated radiation therapy.

Gastric cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Ensuring comprehensive assessment of urinary problems in prostate cancer through patient-physician concordance.

Additional weekly Cetuximab to concurrent chemoradiotherapy in locally advanced non-small cell lung carcinoma: efficacy and safety outcomes of a randomized, multi-center phase II study investigating.

Cost-effectiveness analysis of scalp cooling to reduce chemotherapy-induced alopecia.

The clinical effectiveness and cost-effectiveness of ablative therapies in the management of liver metastases: systematic review and economic evaluation.

Development and validation of a high-performance liquid chromatography-tandem mass spectrometry assay quantifying vemurafenib in human plasma.

Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of CD151.

TCR repertoires of intratumoral T-cell subsets.

Sequential (18)F-FDG PET/CT for early prediction of complete pathological response in breast and axilla during neoadjuvant chemotherapy.

Hot flashes are not predictive for serum concentrations of tamoxifen and its metabolites.

A UV-induced genetic network links the RSC complex to nucleotide excision repair and shows dose-dependent rewiring.

Synchronous BRAF(V600E) and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity.

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

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