Publications

Breast cancer research and treatment

SERPINA6, BEX1, AGTR1, SLC26A3, and LAPTM4B are markers of resistance to neoadjuvant chemotherapy in HER2-negative breast cancer.

01-01-2013

Cancer discovery

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

01-01-2013

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Relating acute esophagitis to radiotherapy dose using FDG-PET in concurrent chemo-radiotherapy for locally advanced non-small cell lung cancer.

01-01-2013

Advances in biological regulation

Structure-function relationships of autotaxin, a secreted lysophospholipase D.

01-01-2013

Cancer research

A preclinical mouse model of invasive lobular breast cancer metastasis.

01-01-2013

BMC medical genomics

Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.

31-12-2012

The Journal of biological chemistry

Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration.

28-12-2012

Genes Dev.: Genes & development

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny

27-12-2012

Proceedings of the National Academy of Sciences of the United States of America

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.

26-12-2012

The oncologist

Critical appraisal of translational research models for suitability in performance assessment of cancer centers.

25-12-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Risk of treatment-related esophageal cancer among breast cancer survivors.

01-12-2012

Pharmaceutical research

Model-based evaluation and optimization of cardiac monitoring protocols for adjuvant treatment of breast cancer with trastuzumab.

01-12-2012

Breast (Edinburgh, Scotland)

Additional value of the 70-gene signature and levels of ER and PR for the prediction of outcome in tamoxifen-treated ER-positive breast cancer.

01-12-2012

Human gene therapy

Rational design of DNA vaccines for the induction of human papillomavirus type 16 E6- and E7-specific cytotoxic T-cell responses.

01-12-2012

Trends in biochemical sciences

Switching Polo-like kinase-1 on and off in time and space.

01-12-2012

Cancer chemotherapy and pharmacology

Pharmacokinetics of eribulin mesylate in patients with solid tumors and hepatic impairment.

01-12-2012

Human brain mapping

Late effects of high-dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: converging results from multimodal magnetic resonance imaging.

01-12-2012

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Lack of tumor uptake of 131-I labeled rituximab in a patient with a CD20 positive lymphoma lesion.

01-12-2012

European journal of nuclear medicine and molecular imaging

Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy.

01-12-2012

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Radioguided occult lesion localisation (ROLL) in breast-conserving surgery after neoadjuvant chemotherapy.

01-12-2012

Proceedings of the National Academy of Sciences of the United States of America

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

27-11-2012

Cell

MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.

21-11-2012

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Efficacy of cognitive behavioral therapy and physical exercise in alleviating treatment-induced menopausal symptoms in patients with breast cancer: results of a randomized, controlled, multicenter trial.

20-11-2012

BMJ (Clinical research ed.)

Commentary: Substandard medicines are the priority for neglected tropical diseases.

14-11-2012

The Journal of biological chemistry

Intrinsic flexibility of ubiquitin on proliferating cell nuclear antigen (PCNA) in translesion synthesis.

09-11-2012

American journal of nuclear medicine and molecular imaging

Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist.

08-11-2012

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

Can adjuvant chemoradiotherapy replace extended lymph node dissection in gastric cancer?

07-11-2012

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

Treatment dilemmas in patients with synchronous colorectal liver metastases.

07-11-2012

Molecular pharmaceutics

Oral availability and brain penetration of the B-RAFV600E inhibitor vemurafenib can be enhanced by the P-GLYCOprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

05-11-2012

Clinical lung cancer

Diffuse reflectance spectroscopy: a new guidance tool for improvement of biopsy procedures in lung malignancies.

01-11-2012

Journal of the European Academy of Dermatology and Venereology : JEADV

Melanoma patients receive more follow-up care than current guideline recommendations: a study of 546 patients from the general Dutch population.

01-11-2012

Clinical pharmacology and therapeutics

Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification.

01-11-2012

DNA repair

Effects of compound heterozygosity at the Xpd locus on cancer and ageing in mouse models.

01-11-2012

Methods (San Diego, Calif.)

Chromosome conformation capture on chip in single Drosophila melanogaster tissues.

01-11-2012

European journal of cancer (Oxford, England : 1990)

Higher prevalence of sexual dysfunction in colon and rectal cancer survivors compared with the normative population: a population-based study.

01-11-2012

Breast cancer research and treatment

Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.

01-11-2012

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Comparing higher order models for the EORTC QLQ-C30.

01-11-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D surface imaging for monitoring intrafraction motion in frameless stereotactic body radiotherapy of lung cancer.

01-11-2012

Cancer chemotherapy and pharmacology

Disposition and metabolism of 14C-dovitinib (TKI258), an inhibitor of FGFR and VEGFR, after oral administration in patients with advanced solid tumors.

01-11-2012

Magnetic resonance imaging

Functional MRI for radiotherapy dose painting.

01-11-2012

Journal of biomedical optics

Optical coherence tomography in vulvar intraepithelial neoplasia.

01-11-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Mediastinal lymph node position variability in non-small cell lung cancer patients treated with radical irradiation.

01-11-2012

Medical physics

Validation of deformable registration in head and neck cancer using analysis of variance.

01-11-2012

Bioanalysis

Quantitative determination of erlotinib and O-desmethyl erlotinib in human EDTA plasma and lung tumor tissue.

01-11-2012

Head & neck

Preoperative imaging and surgical margins in maxillectomy patients.

01-11-2012

European journal of radiology

Reducing the throughput time of the diagnostic track involving CT scanning with computer simulation.

01-11-2012

The Journal of pathology

Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland.

01-11-2012

Methods (San Diego, Calif.)

Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: from fixation to computation.

01-11-2012

Cell

A missing link in genotype-directed cancer therapy.

26-10-2012

British journal of cancer

Risk and prognostic significance of metachronous contralateral testicular germ cell tumours.

23-10-2012