Publications

Molecular pharmacology

Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters.

01-04-2010

European journal of clinical investigation

microRNAs, RNA binding proteins and cancer.

01-04-2010

Molecular imaging and biology

Predicting early chemotherapy response with technetium-99m methoxyisobutylisonitrile SPECT/CT in advanced non-small cell lung cancer.

01-04-2010

Nature cell biology

BRD7 is a candidate tumour suppressor gene required for p53 function.

01-04-2010

Investigational new drugs

Dose-finding and pharmacokinetic study of orally administered indibulin (D-24851) to patients with advanced solid tumors.

01-04-2010

European journal of cancer (Oxford, England : 1990)

Trends in incidence, treatment and survival of gastric adenocarcinoma between 1990 and 2007: a population-based study in the Netherlands.

01-04-2010

Health and quality of life outcomes

Effects of mode of administration (MOA) on the measurement properties of the EORTC QLQ-C30: a randomized study.

30-03-2010

Cancer cell

PICS-ure this: prosenescence therapy?

16-03-2010

Urologia internationalis

Pim1 regulates androgen-dependent survival signaling in prostate cancer cells.

11-03-2010

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Effects of tamoxifen and exemestane on cognitive functioning of postmenopausal patients with breast cancer: results from the neuropsychological side study of the tamoxifen and exemestane adjuvant multinational trial.

10-03-2010

Psycho-oncology

Psychological distress and use of psychosocial support in familial adenomatous polyposis.

01-03-2010

Oncology letters

Serum proteomics and disease-specific biomarkers of patients with advanced gastric cancer.

01-03-2010

Cell death and differentiation

Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation.

01-03-2010

Annals of oncology : official journal of the European Society for Medical Oncology

Postoperative chemoradiotherapy in gastric cancer--a phase I-II study of radiotherapy with dose escalation of weekly cisplatin and daily capecitabine chemotherapy.

01-03-2010

AAPS PharmSciTech

Naked plasmid DNA formulation: effect of different disaccharides on stability after lyophilisation.

01-03-2010

Annals of oncology : official journal of the European Society for Medical Oncology

A simple system for grading the response of breast cancer to neoadjuvant chemotherapy.

01-03-2010

BJU international

Prostate cancer survivors who would be eligible for active surveillance but were either treated with radiotherapy or managed expectantly: comparisons on long-term quality of life and symptom burden.

01-03-2010

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Simultaneous quantification of emtricitabine and tenofovir nucleotides in peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.

01-03-2010

Annals of surgery

Prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers: very low risk for subsequent breast cancer.

01-03-2010

Nederlands tijdschrift voor geneeskunde

[Improved compliance with the 'Melanoma' treatment guideline].

23-02-2010

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Novel therapeutics in combination with radiotherapy to improve cancer treatment: rationale, mechanisms of action and clinical perspective.

20-02-2010

Cancer research

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan.

15-02-2010

International journal of radiation oncology, biology, physics

Radiation-associated breast tumors display a distinct gene expression profile.

01-02-2010

Carcinogenesis

Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.

01-02-2010

Molecular cancer therapeutics

Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation.

01-02-2010

Genome research

Bayesian network analysis of targeting interactions in chromatin.

01-02-2010

European journal of human genetics : EJHG

Attitudes toward genetic testing in childhood and reproductive decision-making for familial adenomatous polyposis.

01-02-2010

Breast cancer research and treatment

The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer.

01-02-2010

Breast (Edinburgh, Scotland)

Factors contributing to improved local control after mastectomy in patients with breast cancer aged 40 years or younger.

01-02-2010

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

First clinical experience with a multiple region of interest registration and correction method in radiotherapy of head-and-neck cancer patients.

01-02-2010

European journal of epidemiology

Reliability of self-reported diagnostic radiation history in BRCA1/2 mutation carriers.

01-02-2010

Investigational new drugs

Two-stage model-based clinical trial design to optimize phase I development of novel anticancer agents.

01-02-2010

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Correction strategies to manage deformations in head-and-neck radiotherapy.

01-02-2010

Molecular oncology

Benchmarking biology research organizations using a new, dedicated tool.

01-02-2010

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D Dosimetric verification of volumetric-modulated arc therapy by portal dosimetry.

01-02-2010

Breast cancer research and treatment

Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers.

01-02-2010

European journal of cancer (Oxford, England : 1990)

Personality is associated with health status and impact of cancer among melanoma survivors.

01-02-2010

Acta oto-laryngologica

No hearing loss after repeated courses of tobramycin in cystic fibrosis patients.

01-02-2010

EMBO reports

Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing.

01-02-2010

Cancer Research

Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach

26-01-2010

Cancer research

Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.

15-01-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients.

15-01-2010

Nederlands tijdschrift voor geneeskunde

[Secondary use of human tissue: consent and better information required].

07-01-2010

Oncogene

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.

07-01-2010

Proceedings of the National Academy of Sciences of the United States of America

Recombination-induced tag exchange to track old and new proteins.

05-01-2010

Biomedical chromatography : BMC

High-performance liquid chromatography coupled with mass spectrometry for the quantitative analysis of vinca-alkaloids in biological matrices: a concise survey from the literature.

01-01-2010

Annals of oncology : official journal of the European Society for Medical Oncology

The impact of inter-observer variation in pathological assessment of node-negative breast cancer on clinical risk assessment and patient selection for adjuvant systemic treatment.

01-01-2010

European journal of cancer (Oxford, England : 1990)

New opportunities for drug outcomes research in cancer patients: the linkage of the Eindhoven Cancer Registry and the PHARMO Record Linkage System.

01-01-2010

Genes & development

Tumorigenicity of the miR-17-92 cluster distilled.

01-01-2010

Laboratory animals

Validation of intratracheal instillation of lung tumour cells in mice using single photon emission computed tomography/computed tomography imaging.

01-01-2010