Publications

Cancer discovery

Patient-derived xenograft models: an emerging platform for translational cancer research.

Nuclear medicine communications

Radio-guided seed localization for breast cancer excision: an ex-vivo specimen-based study to establish the accuracy of a freehand-SPECT device in predicting resection margins.

Journal of oncology practice

Pioneering quality assessment in European cancer centers: a data analysis of the organization for European cancer institutes accreditation and designation program.

Gynecologic oncology

Development and internal validation of a prognostic model to predict recurrence free survival in patients with adult granulosa cell tumors of the ovary.

European urology

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study.

Nature chemical biology

The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity.

Journal of biomedical optics

Monitoring of tumor radio frequency ablation using derivative spectroscopy.

Annals of oncology : official journal of the European Society for Medical Oncology

Still a long way to go to achieve multidisciplinarity for the benefit of patients: commentary on the ESMO position paper (Annals of Oncology 25(1): 9-15, 2014).

International journal of cancer

PI3K/AKT/mTOR pathway activation in primary and corresponding metastatic breast tumors after adjuvant endocrine therapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Effect of compressed sensing reconstruction on target and organ delineation in cone-beam CT of head-and-neck and breast cancer patients.

Nucleic acids research

Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light.

30-08-2014

The Journal of biological chemistry

GPR107, a G-protein-coupled receptor essential for intoxication by Pseudomonas aeruginosa exotoxin A, localizes to the Golgi and is cleaved by furin.

29-08-2014

British journal of cancer

The multigene signature MammaPrint impacts on multidisciplinary team decisions in ER+, HER2- early breast cancer.

26-08-2014

The Journal of experimental medicine

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.

25-08-2014

Cell reports

Balanced activity of three mitotic motors is required for bipolar spindle assembly and chromosome segregation.

21-08-2014

Oncogene

Signaling events mediated by α3β1 integrin are essential for mammary tumorigenesis.

21-08-2014

Nederlands tijdschrift voor geneeskunde

[Hyperglycaemia during treatment with everolimus].

15-08-2014

Oncogene

FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance.

07-08-2014

PloS one

Lack of genomic heterogeneity at high-resolution aCGH between primary breast cancers and their paired lymph node metastases.

02-08-2014

Oncoimmunology

High sensitivity of cancer exome-based CD8 T cell neo-antigen identification.

02-08-2014

Drug metabolism and disposition: the biological fate of chemicals

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

Psycho-oncology

Psychosocial aspects of hereditary cancer (PAHC) questionnaire: development and testing of a screening questionnaire for use in clinical cancer genetics.

Journal of the National Cancer Institute

Cardiovascular morbidity and mortality after treatment for ductal carcinoma in situ of the breast.

Nature cell biology

A growing role for Aurora A in chromosome instability.

European journal of cancer (Oxford, England : 1990)

Review of therapeutic drug monitoring of anticancer drugs part two--targeted therapies.

Molecular & cellular proteomics : MCP

Phosphoproteome dynamics in onset and maintenance of oncogene-induced senescence.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

IMRT limits nephrotoxicity after chemoradiotherapy for gastric cancer.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Chemotherapy-induced peripheral neuropathy and its association with quality of life: a systematic review.

Psycho-oncology

Unmet information needs and impact of cancer in (long-term) thyroid cancer survivors: results of the PROFILES registry.

European journal of cancer (Oxford, England : 1990)

Therapeutic drug monitoring in cancer--are we missing a trick?

Transgenic research

Improved pregnancy and birth rates with routine application of nonsurgical embryo transfer.

Radiation research

The curative outcome of radioimmunotherapy in a mouse breast cancer model relies on mTOR signaling.

Haematologica

Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis.

European journal of nuclear medicine and molecular imaging

Combined use of ¹⁸F-FDG PET/CT and MRI for response monitoring of breast cancer during neoadjuvant chemotherapy.

Cancer research

miR-155 drives telomere fragility in human breast cancer by targeting TRF1.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Preoperative chemoradiotherapy in locally advanced gastric cancer, a phase I/II feasibility and efficacy study.

European journal of cancer (Oxford, England : 1990)

Review of therapeutic drug monitoring of anticancer drugs part 1--cytotoxics.

Experimental hematology

Cellular barcoding: a technical appraisal.

Oncogene

Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

17-07-2014

International journal of biomedical imaging

Detection of melanoma metastases in resected human lymph nodes by noninvasive multispectral photoacoustic imaging.

17-07-2014

Blood

Risk of multiple primary malignancies following treatment of Hodgkin lymphoma.

17-07-2014

The Journal of neuroscience : the official journal of the Society for Neuroscience

Progressive disorganization of paranodal junctions and compact myelin due to loss of DCC expression by oligodendrocytes.

16-07-2014

Cancer research

USP9X downregulation renders breast cancer cells resistant to tamoxifen.

15-07-2014

Molecular cell

Transient activation of p53 in G2 phase is sufficient to induce senescence.

03-07-2014

Pigment cell & melanoma research

Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma.

Seminars in radiation oncology

Magnetic resonance-guided adaptive radiotherapy: a solution to the future.

Breast cancer research and treatment

Use of dried blood spots for the determination of serum concentrations of tamoxifen and endoxifen.

Journal of the National Cancer Institute

Recommended patient-reported core set of symptoms to measure in adult cancer treatment trials.

Clinical pharmacology and therapeutics

Association analysis of genetic polymorphisms in genes related to sunitinib pharmacokinetics, specifically clearance of sunitinib and SU12662.