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Fundamental Research (1)

Fundamental Research

Understanding cancer at its core

To outsmart cancer, we first need to understand it. Our fundamental researchers study the biology of cancer cells in depth: how they differ from healthy cells, how they evolve, and how they respond to stress, treatment and their microenvironment. By uncovering hidden vulnerabilities, they lay the groundwork for future therapies. Curiosity-driven and internationally oriented, this community works in close interaction with clinicians, ensuring that new biological insights can ultimately translate into better care.


What we investigate

How are important processes in the cell regulated?

How do cancer cells differ from normal cells?

How does a cell deal with damage and interventions and how can we exploit this knowledge to optimize treatment?

How do various cell types in the body affect the development of cancer and its response to treatment?
Fundamental research means asking questions before we know their impact. Sustained investment in this curiosity-driven science is essential to enable future breakthroughs that transform cancer care.
Theme leader Fundamental Research

In this video, researchers from the Netherlands Cancer Institute take you along in their quest to understand the fundamental workings of our biology. Many important new therapies are the results of fundamental research, in which you don't know what you'll find before you start. The Netherlands Cancer Institute conducts fundamental research because the opportunities and possibilities are endless.

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