Publications

Cancer

Cognitive deficits after postoperative adjuvant chemotherapy for breast carcinoma.

British journal of cancer

Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG).

Therapeutic drug monitoring

Sampling technique from central venous catheters proves critical for pharmacokinetic studies.

British journal of cancer

Bioavailability and toxicity after oral administration of m-iodobenzylguanidine (MIBG).

Oncogene

Rapid dephosphorylation of p107 following UV irradiation.

21-01-1999

Current biology : CB

Multivesicular body morphogenesis requires phosphatidyl-inositol 3-kinase activity.

14-01-1999

Nature

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.

14-01-1999

Oncogene

Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein.

14-01-1999

Anti-cancer drugs

Topoisomerase I/II inhibitor intoplicine administered as a 24 h infusion: phase I and pharmacologic study.

01-01-1999

British journal of cancer

Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein.

01-01-1999

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Towards prediction and modulation of treatment response.

01-01-1999

Acta oncologica (Stockholm, Sweden)

Radiation-induced apoptosis--the ceramide-SAPK signaling pathway and clinical aspects.

22-12-1998

Investigational new drugs

Pharmaceutical development of a parenteral lyophilized formulation of the investigational antitumor neuropeptide antagonist [Arg6, D-Trp7,9, MePhe8]-Substance P [6-11].

16-12-1998

The EMBO journal

A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

15-12-1998

Seminars in immunology

Tumor necrosis factor receptor family members in the immune system.

01-12-1998

Journal of chromatography. B, Biomedical sciences and applications

High-performance liquid chromatographic bio-analysis of PSC 833 in human and murine plasma.

20-11-1998

Genes & development

Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1.

15-11-1998

Journal of mass spectrometry : JMS

Quantitative determination of Ecteinascidin 743 in human plasma by miniaturized high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Cancer research

High frequency of interactions between lung cancer susceptibility genes in the mouse: mapping of Sluc5 to Sluc14.

Radiation research

Increased expression of glomerular von Willebrand factor after irradiation of the mouse kidney.

Journal of clinical epidemiology

Translation, validation, and norming of the Dutch language version of the SF-36 Health Survey in community and chronic disease populations.

Human mutation

ATM germline mutations in classical ataxia-telangiectasia patients in the Dutch population.

29-10-1998

The Journal of cell biology

Cre-loxP-mediated inactivation of the alpha6A integrin splice variant in vivo: evidence for a specific functional role of alpha6A in lymphocyte migration but not in heart development.

05-10-1998

Molecular and cellular biology

Biosynthesis and function of the modified DNA base beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.

The Annals of pharmacotherapy

Hepatitis during chloroguanide prophylaxis.

Cancer treatment reviews

In-vitro metabolism of anti-cancer drugs, methods and applications: paclitaxel, docetaxel, tamoxifen and ifosfamide.

Clinical cancer research : an official journal of the American Association for Cancer Research

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A.

Journal of chromatography. B, Biomedical sciences and applications

High-performance liquid chromatographic determination of stabilized 4-hydroxyifosfamide in human plasma and erythrocytes.

25-09-1998

Journal of chromatography. B, Biomedical sciences and applications

Simultaneous determination of N,N',N"-triethylenethiophosphoramide, cyclophosphamide and some of their metabolites in plasma using capillary gas chromatography.

25-09-1998

The Journal of experimental medicine

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage.

07-09-1998

Anti-cancer drugs

Phase I and pharmacologic study of weekly doxorubicin and 1 h infusional paclitaxel in patients with advanced breast cancer.

01-09-1998

Pharmacological research

Pharmacologic study of 3-hour 135 mg M-2 paclitaxel in platinum pretreated patients with advanced ovarian cancer.

01-09-1998

Journal of pharmaceutical and biomedical analysis

High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma.

01-09-1998

Journal of chromatography. B, Biomedical sciences and applications

Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.

07-08-1998

Journal of the National Cancer Institute

Availability of PSC833, a substrate and inhibitor of P-glycoproteins, in various concentrations of serum.

05-08-1998

Anti-cancer drugs

O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan.

01-08-1998

Hepatology (Baltimore, Md.)

Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice.

01-08-1998

Journal of cell science

Removal and degradation of the free MHC class II beta chain in the endoplasmic reticulum requires proteasomes and is accelerated by BFA.

01-08-1998

Biochemical and biophysical research communications

Genomic organization of the human alpha 3 integrin subunit gene.

30-07-1998

The Journal of cell biology

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.

13-07-1998

Experimental lung research

Genetics of quantitative and qualitative aspects of lung tumorigenesis in the mouse: multiple interacting Susceptibility to lung cancer (Sluc) genes with large effects.

11-07-1998

Oncogene

Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse.

09-07-1998

Molecular and biochemical parasitology

The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.

European journal of immunology

The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2.

European journal of cancer (Oxford, England : 1990)

Quality of life assessment in daily clinical oncology practice: a feasibility study.

Journal of clinical epidemiology

Comparison of patient and proxy EORTC QLQ-C30 ratings in assessing the quality of life of cancer patients.