Publications

Cancer research

High frequency of interactions between lung cancer susceptibility genes in the mouse: mapping of Sluc5 to Sluc14.

Radiation research

Increased expression of glomerular von Willebrand factor after irradiation of the mouse kidney.

Journal of clinical epidemiology

Translation, validation, and norming of the Dutch language version of the SF-36 Health Survey in community and chronic disease populations.

Human mutation

ATM germline mutations in classical ataxia-telangiectasia patients in the Dutch population.

29-10-1998

The Journal of cell biology

Cre-loxP-mediated inactivation of the alpha6A integrin splice variant in vivo: evidence for a specific functional role of alpha6A in lymphocyte migration but not in heart development.

05-10-1998

Molecular and cellular biology

Biosynthesis and function of the modified DNA base beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.

The Annals of pharmacotherapy

Hepatitis during chloroguanide prophylaxis.

Cancer treatment reviews

In-vitro metabolism of anti-cancer drugs, methods and applications: paclitaxel, docetaxel, tamoxifen and ifosfamide.

Clinical cancer research : an official journal of the American Association for Cancer Research

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A.

Journal of chromatography. B, Biomedical sciences and applications

High-performance liquid chromatographic determination of stabilized 4-hydroxyifosfamide in human plasma and erythrocytes.

25-09-1998

Journal of chromatography. B, Biomedical sciences and applications

Simultaneous determination of N,N',N"-triethylenethiophosphoramide, cyclophosphamide and some of their metabolites in plasma using capillary gas chromatography.

25-09-1998

The Journal of experimental medicine

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage.

07-09-1998

Anti-cancer drugs

Phase I and pharmacologic study of weekly doxorubicin and 1 h infusional paclitaxel in patients with advanced breast cancer.

01-09-1998

Pharmacological research

Pharmacologic study of 3-hour 135 mg M-2 paclitaxel in platinum pretreated patients with advanced ovarian cancer.

01-09-1998

Journal of pharmaceutical and biomedical analysis

High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma.

01-09-1998

Journal of chromatography. B, Biomedical sciences and applications

Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.

07-08-1998

Journal of the National Cancer Institute

Availability of PSC833, a substrate and inhibitor of P-glycoproteins, in various concentrations of serum.

05-08-1998

Anti-cancer drugs

O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan.

01-08-1998

Hepatology (Baltimore, Md.)

Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice.

01-08-1998

Journal of cell science

Removal and degradation of the free MHC class II beta chain in the endoplasmic reticulum requires proteasomes and is accelerated by BFA.

01-08-1998

Biochemical and biophysical research communications

Genomic organization of the human alpha 3 integrin subunit gene.

30-07-1998

The Journal of cell biology

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.

13-07-1998

Experimental lung research

Genetics of quantitative and qualitative aspects of lung tumorigenesis in the mouse: multiple interacting Susceptibility to lung cancer (Sluc) genes with large effects.

11-07-1998

Oncogene

Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse.

09-07-1998

Molecular and biochemical parasitology

The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.

European journal of immunology

The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2.

European journal of cancer (Oxford, England : 1990)

Quality of life assessment in daily clinical oncology practice: a feasibility study.

Journal of clinical epidemiology

Comparison of patient and proxy EORTC QLQ-C30 ratings in assessing the quality of life of cancer patients.

Blood

The bactericidal/permeability-increasing protein (BPI) is present in specific granules of human eosinophils.

15-06-1998

Journal of chromatography. B, Biomedical sciences and applications

Analysis of Ecteinascidin 743, a new potent marine-derived anticancer drug, in human plasma by high-performance liquid chromatography in combination with solid-phase extraction.

12-06-1998

Genes & development

p107 is a suppressor of retinoblastoma development in pRb-deficient mice.

Electrophoresis

High performance density gradient electrophoresis of subcellular organelles, protein complexes and proteins.

Journal of cell science

Ligand-independent role of the beta 4 integrin subunit in the formation of hemidesmosomes.

Anti-cancer drugs

Continuous infusion of low-dose topotecan: pharmacokinetics and pharmacodynamics during a phase II study in patients with small cell lung cancer.

Pharmacological research

The pharmacological role of P-glycoprotein in the intestinal epithelium.

Cancer research

Comparative pharmacology of the novel cyclopropylpyrroloindole-prodrug carzelesin in mice, rats, and humans.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis.

Molecular and cellular biology

Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes.