Publications

Clinical pharmacokinetics

Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

01-06-2020

Drugs in R&D

Combining Isotopic Tracer Techniques to Increase Efficiency of Clinical Pharmacokinetic Trials in Oncology.

01-06-2020

BMJ open

Health-related quality Of Life In patients with advanced Soft TIssue sarcomas treated with Chemotherapy (The HOLISTIC study): protocol for an international observational cohort study.

01-06-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Professional quality of life and burnout amongst radiation oncologists: The impact of alexithymia and empathy.

01-06-2020

PloS one

Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy.

23-05-2020

International journal of pharmaceutics

Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice.

15-05-2020

PloS one

Early budget impact analysis on magnetic seed localization for non-palpable breast cancer surgery.

14-05-2020

Journal of medical Internet research

Web-Based Self-Management for Patients With Lymphoma: Assessment of the Reach of Intervention of a Randomized Controlled Trial.

14-05-2020

European radiology

Value of combined multiparametric MRI and FDG-PET/CT to identify well-responding rectal cancer patients before the start of neoadjuvant chemoradiation.

01-05-2020

Journal of the National Cancer Institute

Trajectories of Cognitive Function Prior to Cancer Diagnosis: A Population-Based Study.

01-05-2020

European journal of cancer (Oxford, England : 1990)

Older versus younger adults with gastric cancer receiving perioperative treatment: Results from the CRITICS trial.

01-05-2020

Nature medicine

High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade.

01-05-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Mise en place: toward neoadjuvant chemoimmunotherapy for early triple-negative breast cancer.

01-05-2020

Psycho-oncology

Unmet information needs of men with breast cancer and health professionals.

01-05-2020

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical assay for the new-generation ROS1/TRK/ALK inhibitor repotrectinib in mouse plasma and tissue homogenate using liquid chromatography-tandem mass spectrometry.

01-05-2020

PloS one

A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition.

29-04-2020

Cellular and molecular gastroenterology and hepatology

Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces Obesity.

25-04-2020

Journal of immunology (Baltimore, Md. : 1950)

IFN-Stimulated Gene 15 Is an Alarmin that Boosts the CTL Response via an Innate, NK Cell-Dependent Route.

15-04-2020

NPJ precision oncology

Accurate surgical navigation with real-time tumor tracking in cancer surgery.

08-04-2020

JAMA oncology

Association Between Immune-Related Adverse Events and Recurrence-Free Survival Among Patients With Stage III Melanoma Randomized to Receive Pembrolizumab or Placebo: A Secondary Analysis of a Randomized Clinical Trial.

01-04-2020

World journal of urology

Best practices in near-infrared fluorescence imaging with indocyanine green (NIRF/ICG)-guided robotic urologic surgery: a systematic review-based expert consensus.

01-04-2020

International journal of cancer

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression.

01-04-2020

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

Hierarchical clustering of PI3K and MAPK pathway proteins in breast cancer intrinsic subtypes.

01-04-2020

Journal of cancer survivorship : research and practice

Type of cancer treatment and cognitive symptoms in working cancer survivors: an 18-month follow-up study.

01-04-2020

British journal of cancer

Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer.

01-04-2020

Nature medicine

Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.

01-04-2020

International journal of radiation oncology, biology, physics

Five-Year Results of the Preoperative Accelerated Partial Breast Irradiation (PAPBI) Trial.

01-04-2020

Nature communications

Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

31-03-2020

Journal of pharmaceutical and biomedical analysis

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma.

20-03-2020

Cancers

Gastrointestinal Stromal Tumours (GIST) in Young Adult (18-40 Years) Patients: A Report from the Dutch GIST Registry.

20-03-2020

International journal of cancer

P-glycoprotein (MDR1/ABCB1) controls brain accumulation and intestinal disposition of the novel TGF-β signaling pathway inhibitor galunisertib.

15-03-2020

Frontiers in oncology

Hippocampus-Related Cognitive and Affective Impairments in Patients With Breast Cancer-A Systematic Review.

11-03-2020

Physical therapy

Education Needs of Dutch Physical Therapists for the Treatment of Patients With Advanced Cancer: A Mixed Methods Study.

10-03-2020

The EMBO journal

In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.

02-03-2020

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Consistency matters: measurement invariance of the EORTC QLQ-C30 questionnaire in patients with hematologic malignancies.

01-03-2020

Journal of neuropathology and experimental neurology

Expression and Cellular Distribution of P-Glycoprotein and Breast Cancer Resistance Protein in Amyotrophic Lateral Sclerosis Patients.

01-03-2020

Medical physics

Erratum: "Investigating the impact of patient arm position in an MR-linac on liver SBRT treatment plans" [Med. Phys. Vol 46, 5144-5151 (2019)].

01-03-2020

Biochemistry and biophysics reports

Biochemical characterization of TRIM72 E3 ligase and its interaction with the insulin receptor substrate 1.

01-03-2020

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

A Deep Learning-based correction to EPID dosimetry for attenuation and scatter in the Unity MR-Linac system.

01-03-2020

Eur J Heart Fail

Myocardial dysfunction in long-term breast cancer survivors treated at ages 40-50 years.

22-02-2020

Key

Trials

GERiatric Screening in the treatment of elderly patients with Ovarian Carcinoma (GERSOC): study protocol for a pragmatic, cluster randomised controlled trial.

22-02-2020

Family practice

Health care use and remaining needs for support among women with breast cancer in the first 15 months after diagnosis: the role of the GP.

19-02-2020

Nat: Nature

Pan-cancer analysis of whole genomes

05-02-2020

The Journal of cell biology

Hemidesmosomes modulate force generation via focal adhesions.

03-02-2020

European journal of heart failure

Myocardial dysfunction in long-term breast cancer survivors treated at ages 40-50 years.

01-02-2020

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction.

01-02-2020

ESMO open

The sarcoma diagnostic interval: a systematic review on length, contributing factors and patient outcomes.

01-02-2020

International journal of clinical pharmacy

Follow up survey for implementation of fixed-dosing of monoclonal antibodies.

01-02-2020

Cancer

Platinum exposure and cause-specific mortality among patients with testicular cancer.

01-02-2020

Molecular & cellular proteomics : MCP

Combined EGFR and ROCK Inhibition in Triple-negative Breast Cancer Leads to Cell Death Via Impaired Autophagic Flux.

01-02-2020