Publications

ESMO open

Durvalumab and tremelimumab plus local partial tumour ablation (radiofrequency ablation or stereotactic radiotherapy) in patients with unresectable liver metastases from metastatic colorectal cancer: results of the EORTC-1560-GITCG multicentre, single-arm phase II study (ILOC).

The Lancet. Digital health

AI as an independent second reader in detection of clinically relevant breast cancers within a population-based screening programme in the Netherlands: a retrospective cohort study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2.

Nature communications

USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism that can temporarily enrich for monoubiquitinated PCNA.

30-07-2025

bioRxiv : the preprint server for biology

Identification of RNA binding proteins that mediate a quality control mechanism of splicing.

23-07-2025

Nature communications

Intestinal tuft cell subtypes represent successive stages of maturation driven by crypt-villus signaling gradients.

22-07-2025

European journal of haematology

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome.

22-07-2025

bioRxiv : the preprint server for biology

MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation.

21-07-2025

Developmental cell

Identifying cross-lineage dependencies of cell-type-specific regulators in mouse gastruloids.

21-07-2025

Methods in cell biology

Assessment of the primary cancer cell secretome using amino acid-analog labeling.

20-07-2025

Molecular cell

Condensin II activation by M18BP1.

17-07-2025

Cell reports. Medicine

Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer.

15-07-2025

Cancer research

Large-scale Characterization of Orthotopic Cell Line-Derived Xenografts Identifies TGFβ Signaling as a Key Regulator of Breast Cancer Morphology and Aggressiveness.

15-07-2025

Cancer cell

Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread.

14-07-2025

Cancer cell

The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets.

14-07-2025

Communications biology

TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination.

11-07-2025

JMIR formative research

Developing and Integrating Digital Sources in an Accessible and Sustainable Online Platform for Adolescents and Young Adult Cancer Survivors: Collaborative Design Approach.

11-07-2025

Science (New York, N.Y.)

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

03-07-2025

NPJ digital medicine

H&E to IHC virtual staining methods in breast cancer: an overview and benchmarking.

02-07-2025

Journal of personalized medicine

Prostate MRI Using Deep Learning Reconstruction in Response to Cancer Screening Demands-A Systematic Review and Meta-Analysis.

02-07-2025

International journal of radiation oncology, biology, physics

Quality of Life and Toxicity in Patients With Pancreatic Ductal Adenocarcinoma Treated With Online Adaptive Stereotactic Magnetic Resonance Guided Radiation Therapy.

Nature genetics

Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers.

Pharmacological research

Resistance to BRAF inhibitors drives melanoma sensitivity to Chk1 inhibition.

Trends in cancer

Prospects for understanding and exploiting the consequences of hyperactivation lethality.

Journal of applied clinical medical physics

Three discipline collaborative radiation therapy (3DCRT) special debate: AI structure segmentation is better than clinician contouring for both OARs and targets.

European radiology

Generalizability, robustness, and correction bias of segmentations of thoracic organs at risk in CT images.

Annals of oncology : official journal of the European Society for Medical Oncology

Prospective randomized phase-II trial of ipilimumab/nivolumab versus standard of care in non-clear cell renal cell cancer - results of the SUNNIFORECAST trial.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Exercise effects on symptoms of depression and anxiety vary by patient, clinical, and intervention characteristics in cancer survivors: Results from pooled analyses of individual participant data of 26 RCTs.

Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine

Application of Machine Learning to Breast MR Imaging.

Genome research

Comprehensive functional annotation of ESR1-driven enhancers in breast cancer reveals hierarchical activity independent of genomic and epigenomic contexts.

Nature medicine

Inherited mitochondrial genetics as a predictor of immune checkpoint inhibition efficacy in melanoma.

Sleep medicine

Sleep quality and overall survival among cancer survivors in the Netherlands: A PROFILES registry study.

Breast cancer research : BCR

Cancer-associated fibroblast driven paracrine IL-6/STAT3 signaling promotes migration and dissemination in invasive lobular carcinoma.

BMC medical informatics and decision making

The impact of a patient decision aid for patients with advanced laryngeal carcinoma - a multicenter study.

Nature genetics

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types.

Nature medicine

Author Correction: Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults.

International journal of radiation oncology, biology, physics

Toward the End of Planning Target Volume Margins With Online Adaptive Radiation Therapy.

Trends in cancer

Treatment of patients with pMMR GI cancers with tumor-infiltrating lymphocytes (TIL): a reality?

Bioorganic & medicinal chemistry

Design, Synthesis, and Biological Implications of Autotaxin inhibitors with a Three-Point lock binding mode.

JAMA network open

Exogenous Hormones, Tumor Intrinsic Subtypes, and Breast Cancer.

Scientific reports

Pretreatment PET dissemination features as biomarkers for survival outcomes in melanoma patients treated with immune-checkpoint inhibitors.

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy of adjuvant therapy in patients with stage IIIA cutaneous melanoma.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Retreatment of Metastatic Castration-Resistant Prostate Cancer Patients with ²²³Ra Therapy in Daily Practice.

British journal of cancer

Rechallenge of ipilimumab and nivolumab in advanced melanoma patients after previous ipilimumab-based therapy.

European journal of cancer (Oxford, England : 1990)

Dose-individualisation of fluoropyrimidines based on pre-treatment serum uracil levels: the Alpe2U study.

European journal of cancer (Oxford, England : 1990)

Neoadjuvant immunotherapy for patients with resectable stage III/IV cutaneous melanoma - A Swedish retrospective real-world study (NEO-MEL).

Cancer immunology, immunotherapy : CII

Dissecting response to neoadjuvant immunotherapy-treated melanoma using cancer-immunity cycle-associated signatures.

Journal for immunotherapy of cancer

SITC vision: Opportunities for deeper understanding of mechanisms of anti-tumor activity, toxicity, and resistance to optimize cancer immunotherapy.