Publications

Cancer research

Large-scale Characterization of Orthotopic Cell Line-Derived Xenografts Identifies TGFβ Signaling as a Key Regulator of Breast Cancer Morphology and Aggressiveness.

15-07-2025

Cancer cell

Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread.

14-07-2025

Cancer cell

The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets.

14-07-2025

Communications biology

TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination.

11-07-2025

JMIR formative research

Developing and Integrating Digital Sources in an Accessible and Sustainable Online Platform for Adolescents and Young Adult Cancer Survivors: Collaborative Design Approach.

11-07-2025

Science (New York, N.Y.)

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

03-07-2025

NPJ digital medicine

H&E to IHC virtual staining methods in breast cancer: an overview and benchmarking.

02-07-2025

Journal of personalized medicine

Prostate MRI Using Deep Learning Reconstruction in Response to Cancer Screening Demands-A Systematic Review and Meta-Analysis.

02-07-2025

International journal of radiation oncology, biology, physics

Quality of Life and Toxicity in Patients With Pancreatic Ductal Adenocarcinoma Treated With Online Adaptive Stereotactic Magnetic Resonance Guided Radiation Therapy.

01-07-2025

Nature genetics

Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers.

01-07-2025

Pharmacological research

Resistance to BRAF inhibitors drives melanoma sensitivity to Chk1 inhibition.

01-07-2025

Trends in cancer

Prospects for understanding and exploiting the consequences of hyperactivation lethality.

01-07-2025

Journal of applied clinical medical physics

Three discipline collaborative radiation therapy (3DCRT) special debate: AI structure segmentation is better than clinician contouring for both OARs and targets.

01-07-2025

European radiology

Generalizability, robustness, and correction bias of segmentations of thoracic organs at risk in CT images.

01-07-2025

Annals of oncology : official journal of the European Society for Medical Oncology

Prospective randomized phase-II trial of ipilimumab/nivolumab versus standard of care in non-clear cell renal cell cancer - results of the SUNNIFORECAST trial.

01-07-2025

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Exercise effects on symptoms of depression and anxiety vary by patient, clinical, and intervention characteristics in cancer survivors: Results from pooled analyses of individual participant data of 26 RCTs.

01-07-2025

Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine

Application of Machine Learning to Breast MR Imaging.

01-07-2025

Genome research

Comprehensive functional annotation of ESR1-driven enhancers in breast cancer reveals hierarchical activity independent of genomic and epigenomic contexts.

01-07-2025

Nature medicine

Inherited mitochondrial genetics as a predictor of immune checkpoint inhibition efficacy in melanoma.

01-07-2025

Sleep medicine

Sleep quality and overall survival among cancer survivors in the Netherlands: A PROFILES registry study.

01-07-2025

Breast cancer research : BCR

Cancer-associated fibroblast driven paracrine IL-6/STAT3 signaling promotes migration and dissemination in invasive lobular carcinoma.

01-07-2025

BMC medical informatics and decision making

The impact of a patient decision aid for patients with advanced laryngeal carcinoma - a multicenter study.

01-07-2025

Nature genetics

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types.

01-07-2025

Nature medicine

Author Correction: Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults.

01-07-2025

International journal of radiation oncology, biology, physics

Toward the End of Planning Target Volume Margins With Online Adaptive Radiation Therapy.

01-07-2025

Trends in cancer

Treatment of patients with pMMR GI cancers with tumor-infiltrating lymphocytes (TIL): a reality?

01-07-2025

Bioorganic & medicinal chemistry

Design, Synthesis, and Biological Implications of Autotaxin inhibitors with a Three-Point lock binding mode.

01-07-2025

JAMA network open

Exogenous Hormones, Tumor Intrinsic Subtypes, and Breast Cancer.

01-07-2025

Scientific reports

Pretreatment PET dissemination features as biomarkers for survival outcomes in melanoma patients treated with immune-checkpoint inhibitors.

01-07-2025

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy of adjuvant therapy in patients with stage IIIA cutaneous melanoma.

01-07-2025

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Retreatment of Metastatic Castration-Resistant Prostate Cancer Patients with ²²³Ra Therapy in Daily Practice.

01-07-2025

British journal of cancer

Rechallenge of ipilimumab and nivolumab in advanced melanoma patients after previous ipilimumab-based therapy.

01-07-2025

European journal of cancer (Oxford, England : 1990)

Dose-individualisation of fluoropyrimidines based on pre-treatment serum uracil levels: the Alpe2U study.

25-06-2025

European journal of cancer (Oxford, England : 1990)

Neoadjuvant immunotherapy for patients with resectable stage III/IV cutaneous melanoma - A Swedish retrospective real-world study (NEO-MEL).

25-06-2025

Cancer immunology, immunotherapy : CII

Dissecting response to neoadjuvant immunotherapy-treated melanoma using cancer-immunity cycle-associated signatures.

25-06-2025

Journal for immunotherapy of cancer

SITC vision: Opportunities for deeper understanding of mechanisms of anti-tumor activity, toxicity, and resistance to optimize cancer immunotherapy.

25-06-2025

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Differences in travel burden between patients with self-reported curable and incurable cancer: results from a Dutch flash mob study.

23-06-2025

Neuro-oncology

Hippocampal avoidance prophylactic cranial irradiation (HA-PCI) for small-cell lung cancer better preserves white matter networks compared to conventional PCI.

21-06-2025

Nucleic acids research

Extrusion fountains are restricted by WAPL-dependent cohesin release and CTCF barriers.

20-06-2025

iScience

A pharmacokinetic study and critical reappraisal of curcumin formulations enhancing bioavailability.

20-06-2025

Nucleic acids research

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair.

20-06-2025

Journal of patient-reported outcomes

Development of a unified system for assessing health related quality of life across the cancer care continuum: the EUonQoL Delphi study to identify priorities for quality of life domains.

19-06-2025

European journal of cancer (Oxford, England : 1990)

Efficacy of encorafenib plus binimetinib in patients with BRAF-mutated melanoma brain metastases: Results from the Dutch Melanoma Treatment Registry.

18-06-2025

Journal of cancer survivorship : research and practice

Health-related quality of life of long-term adolescent and young adult (AYA) cancer survivors compared to a matched normative population: results of the SURVAYA study.

17-06-2025

Cancer research

Immunological Tolerance to Luciferase and Fluorescent Proteins Using Tol Mice Enables Development of Improved Tumor Models for Investigating Immunity and Metastasis.

16-06-2025

bioRxiv : the preprint server for biology

Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies.

15-06-2025

Journal of cancer survivorship : research and practice

Prevalence of and factors associated with clinically important levels of fatigue, pain, and insomnia in survivors of cancer: a population-based cross-sectional study.

14-06-2025

Radiation oncology (London, England)

Implementation of ultra-hypofractionated radiotherapy for breast cancer in the Netherlands in 2020-2023, using registry data and questionnaires.

12-06-2025

Cancer cell

Learning the language of T cell receptors through large-scale screening.

09-06-2025

JCI insight

G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor.

09-06-2025

Large-scale Characterization of Orthotopic Cell Line-Derived Xenografts Identifies TGFβ Signaling as a Key Regulator of Breast Cancer Morphology and Aggressiveness.

Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread.

The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets.

TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination.

Developing and Integrating Digital Sources in an Accessible and Sustainable Online Platform for Adolescents and Young Adult Cancer Survivors: Collaborative Design Approach.

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

H&E to IHC virtual staining methods in breast cancer: an overview and benchmarking.

Prostate MRI Using Deep Learning Reconstruction in Response to Cancer Screening Demands-A Systematic Review and Meta-Analysis.

Quality of Life and Toxicity in Patients With Pancreatic Ductal Adenocarcinoma Treated With Online Adaptive Stereotactic Magnetic Resonance Guided Radiation Therapy.

Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers.

Resistance to BRAF inhibitors drives melanoma sensitivity to Chk1 inhibition.

Prospects for understanding and exploiting the consequences of hyperactivation lethality.

Three discipline collaborative radiation therapy (3DCRT) special debate: AI structure segmentation is better than clinician contouring for both OARs and targets.

Generalizability, robustness, and correction bias of segmentations of thoracic organs at risk in CT images.

Prospective randomized phase-II trial of ipilimumab/nivolumab versus standard of care in non-clear cell renal cell cancer - results of the SUNNIFORECAST trial.

Exercise effects on symptoms of depression and anxiety vary by patient, clinical, and intervention characteristics in cancer survivors: Results from pooled analyses of individual participant data of 26 RCTs.

Application of Machine Learning to Breast MR Imaging.

Comprehensive functional annotation of ESR1-driven enhancers in breast cancer reveals hierarchical activity independent of genomic and epigenomic contexts.

Inherited mitochondrial genetics as a predictor of immune checkpoint inhibition efficacy in melanoma.

Sleep quality and overall survival among cancer survivors in the Netherlands: A PROFILES registry study.

Cancer-associated fibroblast driven paracrine IL-6/STAT3 signaling promotes migration and dissemination in invasive lobular carcinoma.

The impact of a patient decision aid for patients with advanced laryngeal carcinoma - a multicenter study.

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types.

Author Correction: Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults.

Toward the End of Planning Target Volume Margins With Online Adaptive Radiation Therapy.

Treatment of patients with pMMR GI cancers with tumor-infiltrating lymphocytes (TIL): a reality?

Design, Synthesis, and Biological Implications of Autotaxin inhibitors with a Three-Point lock binding mode.

Exogenous Hormones, Tumor Intrinsic Subtypes, and Breast Cancer.

Pretreatment PET dissemination features as biomarkers for survival outcomes in melanoma patients treated with immune-checkpoint inhibitors.

Efficacy of adjuvant therapy in patients with stage IIIA cutaneous melanoma.

Retreatment of Metastatic Castration-Resistant Prostate Cancer Patients with 223Ra Therapy in Daily Practice.

Rechallenge of ipilimumab and nivolumab in advanced melanoma patients after previous ipilimumab-based therapy.

Dose-individualisation of fluoropyrimidines based on pre-treatment serum uracil levels: the Alpe2U study.

Neoadjuvant immunotherapy for patients with resectable stage III/IV cutaneous melanoma - A Swedish retrospective real-world study (NEO-MEL).

Dissecting response to neoadjuvant immunotherapy-treated melanoma using cancer-immunity cycle-associated signatures.

SITC vision: Opportunities for deeper understanding of mechanisms of anti-tumor activity, toxicity, and resistance to optimize cancer immunotherapy.

Differences in travel burden between patients with self-reported curable and incurable cancer: results from a Dutch flash mob study.

Hippocampal avoidance prophylactic cranial irradiation (HA-PCI) for small-cell lung cancer better preserves white matter networks compared to conventional PCI.

Extrusion fountains are restricted by WAPL-dependent cohesin release and CTCF barriers.

A pharmacokinetic study and critical reappraisal of curcumin formulations enhancing bioavailability.

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair.

Development of a unified system for assessing health related quality of life across the cancer care continuum: the EUonQoL Delphi study to identify priorities for quality of life domains.

Efficacy of encorafenib plus binimetinib in patients with BRAF-mutated melanoma brain metastases: Results from the Dutch Melanoma Treatment Registry.

Health-related quality of life of long-term adolescent and young adult (AYA) cancer survivors compared to a matched normative population: results of the SURVAYA study.

Immunological Tolerance to Luciferase and Fluorescent Proteins Using Tol Mice Enables Development of Improved Tumor Models for Investigating Immunity and Metastasis.

Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies.

Prevalence of and factors associated with clinically important levels of fatigue, pain, and insomnia in survivors of cancer: a population-based cross-sectional study.

Implementation of ultra-hypofractionated radiotherapy for breast cancer in the Netherlands in 2020-2023, using registry data and questionnaires.

Learning the language of T cell receptors through large-scale screening.

G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor.

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Retreatment of Metastatic Castration-Resistant Prostate Cancer Patients with ²²³Ra Therapy in Daily Practice.