Publications

Cancer discovery

IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity.

01-07-2024

Cancer chemotherapy and pharmacology

Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.

01-07-2024

Cancer discovery

CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool.

01-07-2024

The Journal of pathology

Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts.

01-07-2024

European journal of drug metabolism and pharmacokinetics

The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review.

01-07-2024

Nature genetics

Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

01-07-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A multicentric randomized controlled phase III trial of adaptive and 18F-FDG-PET-guided dose-redistribution in locally advanced head and neck squamous cell carcinoma (ARTFORCE).

01-07-2024

Nature

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics.

01-07-2024

PNAS nexus

Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair.

01-07-2024

Cancer

Employment outcomes of adolescent and young adult cancer survivors and their partners: A Dutch population-based study.

01-07-2024

Cancer treatment reviews

Agnostic drug development revisited.

01-07-2024

FEBS letters

Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages.

01-07-2024

The Journal of antimicrobial chemotherapy

Skin pharmacokinetics of miltefosine in the treatment of post-kala-azar dermal leishmaniasis in South Asia.

01-07-2024

Medical physics

Impact of cone-beam computed tomography artifacts on dose calculation accuracy for lung cancer.

01-07-2024

Journal for immunotherapy of cancer

Mapping the complexity and diversity of tertiary lymphoid structures in primary and peritoneal metastatic gastric cancer.

01-07-2024

Physics and imaging in radiation oncology

Validation of quantitative magnetic resonance imaging techniques in head and neck healthy structures involved in the salivary and swallowing function: Accuracy and repeatability.

01-07-2024

Cancer chemotherapy and pharmacology

Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.

01-07-2024

Cancer discovery

CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma.

01-07-2024

Psychological medicine

The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: an individual participant data meta-analysis.

01-07-2024

BJU international

^99mTcPSMA-radioguided surgery in oligorecurrent prostate cancer: the randomised TRACE-II trial.

01-07-2024

Cancer discovery

Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally.

01-07-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

European Society of Radiotherapy and Oncology (ESTRO) strategy 2024-2026: Growth and diversification in a rapidly changing world.

01-07-2024

Nature cell biology

Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma.

01-07-2024

Journal for immunotherapy of cancer

Autoantibody-positivity before and seroconversion during treatment with anti-PD-1 is associated with immune-related adverse events in patients with melanoma.

30-06-2024

Biochemical Society transactions

The choreography of chromatin in RNA polymerase III regulation.

26-06-2024

Journal of cancer research and clinical oncology

Can blood-based markers predict RECIST progression in non-small cell lung cancer treated with immunotherapy?

26-06-2024

Cell reports

Gene and protein sequence features augment HLA class I ligand predictions.

25-06-2024

Journal of mammary gland biology and neoplasia

Transcriptomic Analysis of Pubertal and Adult Virgin Mouse Mammary Epithelial and Stromal Cell Populations.

25-06-2024

Journal of mammary gland biology and neoplasia

Rat Models of Hormone Receptor-Positive Breast Cancer.

24-06-2024

Lancet (London, England)

Ductal carcinoma in situ of the breast: finding the balance between overtreatment and undertreatment.

22-06-2024

Nature communications

Widespread chromatin context-dependencies of DNA double-strand break repair proteins.

22-06-2024

iScience

Predicting treatment outcome using kinome activity profiling in HER2+ breast cancer biopsies.

21-06-2024

Scientific reports

Cox proportional hazards regression in small studies of predictive biomarkers.

20-06-2024

NPJ digital medicine

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

20-06-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Use of Sodium Thiosulfate as an Otoprotectant in Patients With Cancer Treated With Platinum Compounds: A Review of the Literature.

20-06-2024

Cell reports. Medicine

The impact of ATP-binding cassette transporters in the diseased brain: Context matters.

18-06-2024

The British journal of radiology

Imaging in the era of risk-adapted treatment in colon cancer.

18-06-2024

Journal of pharmaceutical and biomedical analysis

A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum.

15-06-2024

Nature communications

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

12-06-2024

Cancer cell

The case for therapeutic overactivation of oncogenic signaling as a potential cancer treatment strategy.

10-06-2024

The New England journal of medicine

Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer.

06-06-2024

Molecular cancer

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.

04-06-2024

bioRxiv : the preprint server for biology

Automated classification of cellular expression in multiplexed imaging data with Nimbus.

03-06-2024

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

ABCB1 attenuates brain exposure to the KRAS^G12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure.

01-06-2024

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Common Sense Oncology: Equity, Value, and Outcomes That Matter.

01-06-2024

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Adoptive Cell Therapy for Solid Tumors: Current Status in Melanoma and Next-Generation Therapies.

01-06-2024

FEBS letters

Decoding microtubule detyrosination: enzyme families, structures, and functional implications.

01-06-2024

Diseases of the colon and rectum

An International Expert-Based Consensus on the Definition of a Clinical Near-Complete Response After Neoadjuvant (Chemo)radiotherapy for Rectal Cancer.

01-06-2024

European radiology

Importance and evolution of split scar sign.

01-06-2024

Journal of biomedical optics

Deformable multi-modal image registration for the correlation between optical measurements and histology images.

01-06-2024