Publications

ESMO real world data and digital oncology

From registration to insight: how STRONG AYA transforms registry data to enhance decision-support tools for adolescent and young adult oncology.

Endocrine

Score interpretation thresholds for the European Organisation for Research and Treatment of Cancer thyroid cancer quality of life questionnaire (EORTC QLQ-THY34). An international prospective study.

Journal of medical Internet research

Ethics of Telerehabilitation in Supportive Cancer Care Through a Responsible Innovation Lens.

Oral oncology

Distinct epigenetic signatures define HPV-positive and HPV-negative tonsil carcinomas.

iScience

Cancer cell-intrinsic rewiring of the colorectal cancer secretome.

European journal of nuclear medicine and molecular imaging

Redefining robotic image-guidance - tomographic visualization of lesions during prostate cancer surgery via gantry-free robotic SPECT.

European journal of nuclear medicine and molecular imaging

Real-world use of PSMA imaging in metastatic castration-sensitive prostate cancer: Findings from the CAPRI-3 registry.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

A conceptual model of cancer care and lived experiences in adolescents and young adults with cancer: results from the multi-national European STRONG AYA project.

BMJ open

SCOPES-II: short course of preoperative radiotherapy in head and neck, trunk and extremity soft tissue sarcomas - study protocol for a second randomised phase II clinical trial.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

An Application of Iterative Health Economic Evaluation: An Update on the Early Cost Effectiveness of Whole-Genome Sequencing in Advanced Non-small-Cell Lung Cancer.

Nature aging

Turning CDK4/6 inhibitors against the dark side of senescence.

European urology focus

Oncological Outcomes of Robot-assisted PSMA-guided Salvage Surgery in Recurrent Prostate Cancer: Insights from the Prospective TRACE-I Trial.

Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy

A proof-of-concept study of optical tissue sensing during vacuum-assisted breast biopsy procedures.

Clinical cancer research : an official journal of the American Association for Cancer Research

Transcriptomic Insights into Lobular Breast Cancer Biology and Patient Outcomes: Analysis of the MINDACT Clinical Trial.

The EMBO journal

Alterations in chromatin organization promote totipotent-like features in a DPPA2/DUX-dependent manner.

Cell reports

GRHL and PGR control WNT4 expression via 3D looping of conserved and species-specific enhancers.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Human epididymis protein 4 and risk of malignancy index as risk assessment tools in the decision for referral to an oncology center in patients with an ovarian mass: a cost-effectiveness analysis from a Dutch health care perspective.

Current oncology (Toronto, Ont.)

Coping with an Uncertain or Poor Cancer Prognosis as an Adolescent or Young Adult: A Cross-Sectional Cluster Analysis.

Journal of cancer survivorship : research and practice

Patient-reported outcomes in cancer survivorship: insights from two decades of population-based PROFILES registry research.

European urology oncology

Update of the EORTC Health-related Quality of Life Modules for Bladder Cancer: Phase 1-2 of the Development Process.

European journal of cancer (Oxford, England : 1990)

BRAF^V600E-mutated central nervous system tumors benefit from treatment with dabrafenib plus trametinib: Results from the Drug Rediscovery Protocol.

FEBS open bio

Optimizing photoactivation of PA-mCherry for optical pooled CRISPR screens.

Clinical cancer research : an official journal of the American Association for Cancer Research

plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis-Derived Variants in Liquid Biopsies from Patients with Solid Tumors.

International journal for quality in health care : journal of the International Society for Quality in Health Care

The role of surgical margins as outcome metrics in a quality assurance program for robot-assisted radical prostatectomy.

Psycho-oncology

Understanding Physical Activity in Patients With Metastatic Breast Cancer: An Analysis Rooted in the Theory of Planned Behaviour.

Psycho-oncology

Managing Cancer and Living Meaningfully (CALM) for Patients With Metastatic Cancer and Treatment Response.

International journal of computer assisted radiology and surgery

Machine learning-based treatment outcome prediction in head and neck cancer using integrated noninvasive diagnostics.

Cell reports. Medicine

Liver metastases dampen IL18-driven γδ T cell activity and immunotherapy responsiveness in colorectal cancer.

Breast (Edinburgh, Scotland)

Trends in local, regional and contralateral breast tumor recurrence within five years after diagnosis in the Netherlands: a population-based study including 121347 patients.

European urology oncology

Novel Molecular Biomarkers to Guide Treatment Decision-making in Metastatic Urothelial Cancer-A Patient Cohort Analysis.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

ESMO-ESTRO consensus statements on the safety of combining radiotherapy with CDK4/6, HER2, PARP, or mTOR inhibitors.

Cancer research

Chemotherapy-Treated Breast Cancer Cells Activate the WNT Signaling Pathway to Enter a Diapause-Like Early Persister State.

Cancer discovery

Microbial Metabolic Pathways Guide Response to Immune Checkpoint Blockade Therapy.

ESMO open

Added value of tumor-stroma ratio to postsurgery circulating tumor DNA and pTN stage in risk stratification of patients with stage III colon cancer treated with adjuvant chemotherapy.

Journal of cancer survivorship : research and practice

Health-related conditions among long-term cancer survivors diagnosed in adolescence and young adulthood (AYA): results of the SURVAYA study.

Therapeutic drug monitoring

Therapeutic Drug Monitoring of Oral Targeted Anticancer Drugs: Achievements, Experiences, Challenges, and the Path Forward.

Cell

Choreography of rapid actin filament disassembly by coronin, cofilin, and AIP1.

Frontiers in oncology

Perforator mapping for head and neck reconstructive surgery: a novel personalized approach using magnetic resonance angiography based 3D models and 3D-printing.

ESMO open

Minimum standards of specialist adolescent and young adult (AYA) cancer care units: recommendations and implementation roadmap.

European radiology

Detection rates for prostate cancer using PI-RADS 2.1 upgrading rules in transition zone lesions align with risk assessment categories: a systematic review and meta-analysis.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Changes in bone marrow fat fraction and immune cell counts in women with cervical cancer treated with primary chemoradiotherapy.

Communications medicine

Clinical, pathological and molecular characteristics of patients with disease recurrence despite pathologic response to neoadjuvant ipilimumab plus nivolumab in stage III melanoma.

iScience

A 3D genome compendium of breast cancer progression.

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene

Nature medicine

Publisher Correction: Personalized, autologous neoantigen-specific T cell therapy in metastatic melanoma: a phase 1 trial.

Annals of surgery

Association of Lateral Pelvic Lymph Nodes with Disease Recurrence and Organ Preservation in Patients with Distal Rectal Adenocarcinoma Treated with Total Neoadjuvant Therapy.

Clinical pharmacology and therapeutics

Implementing Pre-Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects.

Nature communications

USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism that can temporarily enrich for monoubiquitinated PCNA.

Nature communications

Intestinal tuft cell subtypes represent successive stages of maturation driven by crypt-villus signaling gradients.

Science (New York, N.Y.)

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.