Publications

Cell reports. Medicine

Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.

15-11-2022

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an ultra-high performance liquid chromatography coupled to tandem mass spectrometry method for the quantification of the antileishmanial drug paromomycin in human skin tissue.

15-11-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

14-11-2022

Cancers

Features on Endoscopy and MRI after Treatment with Contact X-ray Brachytherapy for Rectal Cancer: Explorative Results.

13-11-2022

NPJ breast cancer

Deep learning for fully-automated nuclear pleomorphism scoring in breast cancer.

08-11-2022

Journal of plastic surgery and hand surgery

Surgical flap delay to allow primary transabdominal transplantation of extended rectus abdominis myocutaneous flaps in increasingly complex pelvic wound reconstructions.

08-11-2022

BMJ open

Cohort profile: Risk and risk factors for female breast cancer after treatment for childhood and adolescent cancer: an internationally pooled cohort.

07-11-2022

The Journal of cell biology

Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin.

07-11-2022

Bio-protocol

An Unbiased CRISPR-Cas9 Screening Method for the Identification of Positive and Negative Regulatory Proteins of Cell Adhesion.

05-11-2022

Cancer research

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.

02-11-2022

Cancer discovery

UNCAN.eu, a European Initiative to UNderstand CANcer.

02-11-2022

Nature communications

MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling.

02-11-2022

European journal of cancer (Oxford, England : 1990)

Characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis: A retrospective multicentre cohort study.

01-11-2022

Epidemiology (Cambridge, Mass.)

The Authors Respond.

01-11-2022

Cancer chemotherapy and pharmacology

Idiopathic hyperammonemic encephalopathy secondary to gemcitabine-cisplatin treatment.

01-11-2022

European journal of cancer (Oxford, England : 1990)

Ten-year follow-up of the observational RASTER study, prospective evaluation of the 70-gene signature in ER-positive, HER2-negative, node-negative, early breast cancer.

01-11-2022

Trends in genetics : TIG

Slippy-Sloppy translation: a tale of programmed and induced-ribosomal frameshifting.

01-11-2022

Gynecologic oncology

Peroperative extent of peritoneal metastases affects the surgical outcome and survival in advanced ovarian cancer.

01-11-2022

Clinical pharmacokinetics

Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates.

01-11-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Validation of cancer-type-dependent benefit from immune checkpoint blockade in TMB-H tumors identified by the FoundationOne CDx assay.

01-11-2022

European journal of cancer (Oxford, England : 1990)

Imaging standardisation in metastatic colorectal cancer: A joint EORTC-ESOI-ESGAR expert consensus recommendation.

01-11-2022

Lung cancer (Amsterdam, Netherlands)

Development of an updated, standardized, patient-centered outcome set for lung cancer.

01-11-2022

Preventive medicine

Guidance for setting international standards on reporting longitudinal adherence to stool-based colorectal cancer screening.

01-11-2022

Nature medicine

Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome.

01-11-2022

The Journal of pathology

R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer.

01-11-2022

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Integrated MRI-linac systems: The new paradigm for precision adaptive radiotherapy and biological image-guidance?

01-11-2022

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Robot-Assisted Prostate-Specific Membrane Antigen-Radioguided Surgery in Primary Diagnosed Prostate Cancer.

01-11-2022

European journal of cancer (Oxford, England : 1990)

Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.

01-11-2022

NEJM evidence

Five-Year Analysis of Adjuvant Pembrolizumab or Placebo in Stage III Melanoma.

01-11-2022

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Mindfulness is associated with severity of peripheral neuropathy and related patient-reported outcomes among colorectal cancer patients.

01-11-2022

Nature cancer

cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis.

01-11-2022

Cancer treatment reviews

Retrospective observational studies in ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society (CTOS) community of experts on the minimum requirements for the evaluation of activity of systemic treatments.

01-11-2022

Biomedical chromatography : BMC

Bioanalytical assay for the quantification of the tyrosine kinase inhibitor EAI045 and its major metabolite PIA in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

01-11-2022

Annals of oncology : official journal of the European Society for Medical Oncology

ESMO Expert Consensus Statements on Cancer Survivorship: promoting high-quality survivorship care and research in Europe.

01-11-2022

The Journal of urology

Financial Toxicity After Robot-Assisted Radical Prostatectomy and Its Relation with Oncologic, Functional Outcomes.

01-11-2022

British journal of cancer

Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors.

01-11-2022

Journal of clinical and experimental neuropsychology

Standardized item selection for alternate computerized versions of Rey Auditory Verbal Learning Test(-based) word lists.

01-11-2022

Journal of geriatric oncology

Validation of the 70-gene signature test (MammaPrint) to identify patients with breast cancer aged ≥ 70 years with ultralow risk of distant recurrence: A population-based cohort study.

01-11-2022

European journal of cancer care

Feasibility of a supervised and home-based tailored exercise intervention in head and neck cancer patients during chemoradiotherapy.

01-11-2022

Seminars in cancer biology

Therapy-induced shaping of the glioblastoma microenvironment: Macrophages at play.

01-11-2022

Nature communications

A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.

28-10-2022

Cancers

A Negative Body Image among Adolescent and Young Adult (AYA) Cancer Survivors: Results from the Population-Based SURVAYA Study.

26-10-2022

Cancer research communications

Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy.

26-10-2022

Developmental cell

MYO10-filopodia support basement membranes at pre-invasive tumor boundaries.

24-10-2022

Breast cancer research : BCR

PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients.

21-10-2022

Insights into imaging

Retrospective evaluation of national MRI reporting quality for lateral lymph nodes in rectal cancer patients and concordance with prospective re-evaluation following additional training.

20-10-2022

Molecular cell

DNA-PKcs promotes fork reversal and chemoresistance.

20-10-2022

Molecular cell

Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential.

20-10-2022

eLife

Quantifying how post-transcriptional noise and gene copy number variation bias transcriptional parameter inference from mRNA distributions.

17-10-2022

Cancer research

Boosting Antitumor Immunity with an Expanded Neoepitope Landscape.

17-10-2022

Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.

Development and validation of an ultra-high performance liquid chromatography coupled to tandem mass spectrometry method for the quantification of the antileishmanial drug paromomycin in human skin tissue.

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

Features on Endoscopy and MRI after Treatment with Contact X-ray Brachytherapy for Rectal Cancer: Explorative Results.

Deep learning for fully-automated nuclear pleomorphism scoring in breast cancer.

Surgical flap delay to allow primary transabdominal transplantation of extended rectus abdominis myocutaneous flaps in increasingly complex pelvic wound reconstructions.

Cohort profile: Risk and risk factors for female breast cancer after treatment for childhood and adolescent cancer: an internationally pooled cohort.

Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin.

An Unbiased CRISPR-Cas9 Screening Method for the Identification of Positive and Negative Regulatory Proteins of Cell Adhesion.

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.

UNCAN.eu, a European Initiative to UNderstand CANcer.

MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling.

Characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis: A retrospective multicentre cohort study.

The Authors Respond.

Idiopathic hyperammonemic encephalopathy secondary to gemcitabine-cisplatin treatment.

Ten-year follow-up of the observational RASTER study, prospective evaluation of the 70-gene signature in ER-positive, HER2-negative, node-negative, early breast cancer.

Slippy-Sloppy translation: a tale of programmed and induced-ribosomal frameshifting.

Peroperative extent of peritoneal metastases affects the surgical outcome and survival in advanced ovarian cancer.

Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates.

Validation of cancer-type-dependent benefit from immune checkpoint blockade in TMB-H tumors identified by the FoundationOne CDx assay.

Imaging standardisation in metastatic colorectal cancer: A joint EORTC-ESOI-ESGAR expert consensus recommendation.

Development of an updated, standardized, patient-centered outcome set for lung cancer.

Guidance for setting international standards on reporting longitudinal adherence to stool-based colorectal cancer screening.

Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome.

R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer.

Integrated MRI-linac systems: The new paradigm for precision adaptive radiotherapy and biological image-guidance?

Robot-Assisted Prostate-Specific Membrane Antigen-Radioguided Surgery in Primary Diagnosed Prostate Cancer.

Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.

Five-Year Analysis of Adjuvant Pembrolizumab or Placebo in Stage III Melanoma.

Mindfulness is associated with severity of peripheral neuropathy and related patient-reported outcomes among colorectal cancer patients.

cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis.

Retrospective observational studies in ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society (CTOS) community of experts on the minimum requirements for the evaluation of activity of systemic treatments.

Bioanalytical assay for the quantification of the tyrosine kinase inhibitor EAI045 and its major metabolite PIA in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

ESMO Expert Consensus Statements on Cancer Survivorship: promoting high-quality survivorship care and research in Europe.

Financial Toxicity After Robot-Assisted Radical Prostatectomy and Its Relation with Oncologic, Functional Outcomes.

Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors.

Standardized item selection for alternate computerized versions of Rey Auditory Verbal Learning Test(-based) word lists.

Validation of the 70-gene signature test (MammaPrint) to identify patients with breast cancer aged ≥ 70 years with ultralow risk of distant recurrence: A population-based cohort study.

Feasibility of a supervised and home-based tailored exercise intervention in head and neck cancer patients during chemoradiotherapy.

Therapy-induced shaping of the glioblastoma microenvironment: Macrophages at play.

A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.

A Negative Body Image among Adolescent and Young Adult (AYA) Cancer Survivors: Results from the Population-Based SURVAYA Study.

Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy.

MYO10-filopodia support basement membranes at pre-invasive tumor boundaries.

PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients.

Retrospective evaluation of national MRI reporting quality for lateral lymph nodes in rectal cancer patients and concordance with prospective re-evaluation following additional training.

DNA-PKcs promotes fork reversal and chemoresistance.

Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential.

Quantifying how post-transcriptional noise and gene copy number variation bias transcriptional parameter inference from mRNA distributions.

Boosting Antitumor Immunity with an Expanded Neoepitope Landscape.

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