Publications

Current treatment options in oncology

Immunotherapy for Metastatic Triple Negative Breast Cancer: Current Paradigm and Future Approaches.

01-06-2023

NPJ breast cancer

Immune landscape of breast tumors with low and intermediate estrogen receptor expression.

13-05-2023

Oncoimmunology

Neoadjuvant immune checkpoint blockade triggers persistent and systemic T_reg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.

24-04-2023

The oncologist

Beyond Skin Rash: Alpelisib-Induced Anaphylactic Reactions.

22-04-2023

Nature cancer

PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial.

01-04-2023

Annals of oncology : official journal of the European Society for Medical Oncology

Corrigendum to "Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer": [Annals of Oncology 33 (2022) 769-785].

01-03-2023

International journal of molecular sciences

Triple-Negative Breast Cancer and Predictive Markers of Response to Neoadjuvant Chemotherapy: A Systematic Review.

03-02-2023

Clinical cancer research : an official journal of the American Association for Cancer Research

Facts and hopes in immunotherapy for early-stage triple-negative breast cancer.

09-01-2023

Cancer cell

IL-5-producing CD4⁺ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.

09-01-2023

Nature communications

Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.

21-11-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Validation of cancer-type-dependent benefit from immune checkpoint blockade in TMB-H tumors identified by the FoundationOne CDx assay.

01-11-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.

01-08-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy.

20-07-2022

Nature communications

Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.

27-06-2022

Expert opinion on investigational drugs

Progress and pitfalls in the use of immunotherapy for patients with triple negative breast cancer.

01-06-2022

British journal of cancer

Adjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients.

01-06-2022

NPJ breast cancer

Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer.

28-04-2022

Nature cancer

LCOR mediates interferon-independent tumor immunogenicity and responsiveness to immune-checkpoint blockade in triple-negative breast cancer.

01-03-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments.

01-03-2022

Virchows Archiv : an international journal of pathology

Incorporation of TILs in daily breast cancer care: how much evidence can we bear?

01-01-2022

Breast care (Basel, Switzerland)

Carboplatin-Cyclophosphamide or Paclitaxel without or with Bevacizumab as First-Line Treatment for Metastatic Triple-Negative Breast Cancer (BOOG 2013-01).

01-12-2021

NPJ breast cancer

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

01-12-2021

Science translational medicine

Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers.

27-10-2021

Cancers

Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Study. A Report on Behalf of the International Immuno-Oncology Biomarker Working Group.

29-09-2021

Nature communications

Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer.

27-09-2021

Annals of oncology : official journal of the European Society for Medical Oncology

Reply to: 'Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab.' by D. Fabrizio et al.

01-09-2021

Annals of oncology : official journal of the European Society for Medical Oncology

'IMpassionate conflicts' in immunotherapy trials for metastatic triple-negative breast cancer.

01-08-2021

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Simultaneous analysis of E1 and E2 by LC-MS/MS in healthy volunteers: estimation of reference intervals and comparison with a conventional E2 immunoassay.

15-07-2021

Annals of oncology : official journal of the European Society for Medical Oncology

High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types.

01-05-2021

Cancers

A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer.

16-01-2021

European journal of cancer (Oxford, England : 1990)

Adjuvant chemotherapy in small node-negative triple-negative breast cancer.

01-08-2020

Molecular cancer research : MCR

The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast Cancers.

01-07-2020

NPJ breast cancer

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.

22-05-2020

NPJ breast cancer

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

16-05-2020

NPJ breast cancer

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group.

16-05-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Mise en place: toward neoadjuvant chemoimmunotherapy for early triple-negative breast cancer.

01-05-2020

Nature medicine

Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.

01-04-2020

The Journal of pathology

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.

01-04-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy of chemotherapy and atezolizumab in patients with non-small-cell lung cancer receiving antibiotics and proton pump inhibitors: pooled post hoc analyses of the OAK and POPLAR trials.

01-04-2020

European journal of cancer (Oxford, England : 1990)

Tumour-infiltrating lymphocytes (TILs) and BRCA-like status in stage III breast cancer patients randomised to adjuvant intensified platinum-based chemotherapy versus conventional chemotherapy.

01-03-2020

Breast cancer research : BCR

Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer.

26-12-2019

Breast cancer research : BCR

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes.

07-08-2019

Nature medicine

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

01-07-2019

ESMO open

How I treat MSI cancers with advanced disease.

25-06-2019

Nature medicine

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

01-06-2019

Insights into imaging

Cryoablation and immunotherapy: an overview of evidence on its synergy.

20-05-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors.

01-02-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Passion for immune checkpoint blockade in triple negative breast cancer: Comment on the IMpassion130 study.

01-01-2019

Oncoimmunology

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival.

14-12-2018

Seminars in cancer biology

Immuno-oncology-101: overview of major concepts and translational perspectives.

01-10-2018