Publications

Cancer treatment reviews

High-dose chemotherapy regimens for solid tumors.

01-03-1995

Journal of cancer research and clinical oncology

The use of the Calvert formula to determine the optimal carboplatin dosage.

01-01-1995

Cancer chemotherapy and pharmacology

Isolation, purification, and biological activity of mono- and dihydroxylated paclitaxel metabolites from human feces.

01-01-1995

British journal of cancer

Melphalan tissue concentrations in patients treated with regional isolated perfusion for melanoma of the lower limb.

01-07-1994

Cell

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.

20-05-1994

Annals of oncology : official journal of the European Society for Medical Oncology

Intraperitoneal-administered carboplatin in patients with ovarian cancer; influence of a dwell-time on toxicity and response.

01-02-1994

Journal of chromatography

Fully automated high-performance liquid chromatographic method for the determination of carzelesin (U-80,244) and metabolites (U-76,073 and U-76,074) in human plasma.

14-01-1994

Cancer chemotherapy and pharmacology

Validation of a limited sampling model for carboplatin in a high-dose chemotherapy combination.

01-01-1994

Cancer chemotherapy and pharmacology

Pharmaceutical development of a parenteral lyophilized formulation of the novel indoloquinone antitumor agent EO9.

01-01-1994

Cancer chemotherapy and pharmacology

The pharmacokinetics of reduced folates after intraperitoneal and intravenous administration of racemic [6S,R]-folinic acid.

01-01-1994

Annals of oncology : official journal of the European Society for Medical Oncology

Etoposide, leucovorin, 5-fluorouracil (ELF) combination chemotherapy for advanced gastric cancer: experience with two treatment schedules incorporating intravenous or oral etoposide.

01-01-1994

Cancer chemotherapy and pharmacology

Lithium pharmacokinetics during cisplatin-based chemotherapy: a case report.

01-01-1994

Investigational new drugs

Pharmaceutical development of a parenteral formulation of the novel anti-tumor agent carzelesin (U-80,244).

01-01-1994

Cancer chemotherapy and pharmacology

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinleucinol in mice as determined by high-performance liquid chromatography.

01-01-1994

Pharmacy world & science : PWS

Signal transduction pathways: new targets in oncology.

17-12-1993

Journal of pharmaceutical and biomedical analysis

Chemical stability of the new antitumour agent intoplicine in infusion fluids.

01-11-1993

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients.

01-11-1993

Anticancer research

Clinical pharmacokinetics and pharmacodynamics of anticancer agents in pediatric patients (review).

01-09-1993

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical stability of the cardioprotective agent ICRF-187 in infusion fluids.

01-07-1993

Investigational new drugs

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinorelbine in mice as determined by high performance liquid chromatography.

01-05-1993

Cancer research

Plasma pharmacokinetics of vinblastine and the investigational Vinca alkaloid N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate in mice as determined by high-performance liquid chromatography.

01-05-1993

Cancer chemotherapy and pharmacology

Tissue disposition, excretion and metabolism of vinblastine in mice as determined by high-performance liquid chromatography.

01-01-1993

European journal of cancer (Oxford, England : 1990)

Reconstitution of recombinant interleukin-2 (rIL-2): a comparative study of various rIL-2 muteins.

01-01-1993

Anticancer research

Pharmacology, bio-analysis and pharmacokinetics of the vinca alkaloids and semi-synthetic derivatives (review).

01-09-1992

Pharmaceutisch weekblad. Scientific edition

New cytotoxic drugs and targets in oncology.

21-08-1992

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical stability of two sterile, parenteral formulations of cyclophosphamide (Endoxan) after reconstitution and dilution in commonly used infusion fluids.

01-07-1992

British journal of cancer

A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part I: Clinical aspects.

01-05-1992

Journal of chromatography

Bioanalysis of the investigational anti-tumour drug 5,10-dideaza-5,6,7,8-tetrahydrofolic acid by high-performance liquid chromatography with ultraviolet detection.

15-04-1992

The Annals of pharmacotherapy

Effect of cisplatin-containing chemotherapy on lithium serum concentrations.

01-04-1992

Journal of chromatography

Biodetermination of N-(deacetyl-O-4-vinblastoyl-23)-L-tryptophan, a metabolite of vintriptol, by high-performance liquid chromatography with fluorescence detection.

14-02-1992

Journal of chromatography

Bio-analysis of vinorelbine by high-performance liquid chromatography with fluorescence detection.

17-01-1992

Journal of chromatography

High-performance liquid chromatographic determination of vinblastine, 4-O-deacetylvinblastine and the potential metabolite 4-O-deacetylvinblastine-3-oic acid in biological fluids.

16-08-1991

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical and physical stability of etoposide and teniposide in commonly used infusion fluids.

01-03-1991

Journal of pharmaceutical and biomedical analysis

Analytical methods for the determination of vinca alkaloids in biological specimens: a survey of the literature.

01-01-1991

Journal of pharmaceutical and biomedical analysis

HPLC determination of doxorubicin, doxorubicinol and four aglycone metabolites in plasma of AIDS patients.

01-01-1991

European journal of cancer (Oxford, England : 1990)

Phase I study of vintriptol, a tryptophan ester of vinblastine.

01-01-1991

Journal of pharmaceutical and biomedical analysis

Gas chromatographic analysis, with electron capture detection, of the antifungal drug fluconazole in microvolumes of human plasma.

01-01-1991

DICP : the annals of pharmacotherapy

Chemical stability of suramin in commonly used infusion fluids.

01-11-1990

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical stability of the antitumor drug mitomycin C in solutions for intravesical instillation.

01-11-1990

Journal of chromatography

High-performance liquid chromatographic bio-analysis and preliminary pharmacokinetics of the experimental antitumour drug vintriptol.

03-08-1990

Journal of chromatography

High-performance liquid chromatographic method for the analysis of 10-ethyl-10-deaza-aminopterin and metabolites in plasma.

13-07-1990

Journal of pharmaceutical and biomedical analysis

Gas chromatographic analysis, with nitrogen detection, of tocainide in plasma.

01-01-1990

Journal of pharmaceutical and biomedical analysis

Bio-analysis of N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate, methane sulphonate (VileE) by high-performance liquid chromatography with fluorescence detection.

01-01-1990

Journal of chromatography

Stable and sensitive method for the simultaneous determination of N5-methyltetrahydrofolate, leucovorin, methotrexate and 7-hydroxymethotrexate in biological fluids.

24-03-1989

Journal of pharmaceutical and biomedical analysis

High-performance liquid chromatographic bioanalysis of anthracycline cytostatic drugs.

01-01-1988